Overview
Presents animal models mimicking human stroke to provide insights into the underlying pathophysiology
Discusses various rodent stroke models, including their strengths and limitations
Summarizes the challenges and advances in the treatment and prevention of ischemic stroke
Reviews neuroprotective agents to treat and prevent ischemic stroke
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Table of contents (8 chapters)
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Front Matter
Keywords
About this book
This book summarizes various tools and techniques used to provide insights into the cellular and molecular pathophysiology of stroke. It also presents rodent animal models to help shed light on the pathophysiology of ischemic stroke.
Presenting the latest information on the different types of stroke, including embolic, filament, photothrombotic, and bilateral common carotid artery, the book also describes techniques that are used for confirmation of stroke surgery, such as laser speckle imaging (LSI) and laser Doppler flowmetry (LDF), and discusses the non-human primates that are used in stroke surgery, cerebral venous sinuous thrombosis, and neurobehavioral assessment. Lastly, it analyzes various neuroprotective agents to treat and prevent ischemic stroke, and examines the challenges and advances in treating and preventing acute ischemic stroke.Editors and Affiliations
About the editors
Dr. Amit Kumar Tripathi is a post-doctoral scientist at the School of Biomedical Engineering, Indian Institute of Technology (Banaras Hindu University). He completed his PhD in Endocrinology from CSIR-Central Drug Research Institute, Lucknow, and the Department of Biochemistry, Jamia Hamdard, New Delhi. His doctoral research focused on mechanistic studies to understand neuroprotection and therapeutic targets. He has ten years of research experience in the field of rodent models of various neurosurgical techniques, such as for transient middle cerebral artery occlusion (tMCAO) and cerebral venous sinuses thrombosis (CVS). He has published his research in several peer-reviewed international journals, including the Journal of Biomedical Science and Circulation Research. He is a member of several international scientific societies, including the International Society for Neurochemistry and Society of Toxicology India.
Dr. Abhishek Kumar Singh is an Assistant Professor at Amity Institute of Neuropsychology and Neurosciences, Amity University, Noida, where he has established the state-of-the-art Laboratory for Stem Cell Biology and Neuroscience. He has received his PhD from the CSIR-Indian Institute of Toxicology Research, Lucknow and Department of Biotechnology, Jamia Hamdard, New Delhi, in 2013.
Dr. Singh has published several research articles in respected international journals and book chapters. He is a member of various international scientific societies, including the Indian Academy of Neuroscience and Society of Toxicology India.
Bibliographic Information
Book Title: Models and Techniques in Stroke Biology
Editors: Amit Kumar Tripathi, Abhishek Kumar Singh
DOI: https://doi.org/10.1007/978-981-33-6679-4
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2021
Hardcover ISBN: 978-981-33-6678-7Published: 31 March 2021
Softcover ISBN: 978-981-33-6681-7Published: 01 April 2022
eBook ISBN: 978-981-33-6679-4Published: 30 March 2021
Edition Number: 1
Number of Pages: VII, 115
Number of Illustrations: 2 b/w illustrations, 9 illustrations in colour
Topics: Neurosciences, Developmental Biology, Biological Techniques