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Cancer Cytogenetics

Methods and Protocols

  • Book
  • © 2003

Overview

Editors:
  1. John Swansbury

    1. The Royal Marsden NHS Trust, The Institute of Cancer Research, Sutton, UK

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Part of the book series: Methods in Molecular Biology (MIMB, volume 220)

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Table of contents (18 protocols)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Introduction

    • John Swansbury
    Pages 1-8

  3. Cytogenetic Studies in Hematologic Malignancies

    • John Swansbury
    Pages 9-22

  4. The Myeloid Disorders

    • John Swansbury
    Pages 23-42

  5. Cytogenetic Techniques for Myeloid Disorders

    • John Swansbury
    Pages 43-57

  6. Acute Lymphoblastic Leukemia

    • John Swansbury
    Pages 59-71

  7. Conventional Cytogenetic Techniques in the Diagnosis of Childhood Acute Lymphoblastic Leukemia

    • Susana C. Raimondi, Susan Mathew
    Pages 73-82

  8. Chromosome Preparations from Bone Marrow in Acute Lymphoblastic Leukemia

    • Ann Watmore
    Pages 83-91

  9. Lymphoid Disorders Other than Common Acute Lymphoblastic Leukemia

    • John Swansbury
    Pages 93-110

  10. Other Lymphoid Malignancies

    • John Swansbury
    Pages 111-123

  11. Cytogenetic and Genetic Studies in Solid Tumors

    • John Swansbury
    Pages 125-133

  12. Human Solid Tumors

    • Pietro Polito, Paola Dal Cin, Maria Debiec-Rychter, Anne Hagemeijer
    Pages 135-150

  13. Analysis and Interpretation of Cytogenetic Findings in Malignancy

    • John Swansbury
    Pages 151-171

  14. Cytogenetic Studies Using FISH

    • Toon Min, John Swansbury
    Pages 173-191

  15. FISH Techniques

    • Toon Min
    Pages 193-212

  16. FISH, CGH, and SKY in the Diagnosis of Childhood Acute Lymphoblastic Leukemia

    • Susan Mathew, Susana C. Raimondi
    Pages 213-233

  17. Solving Problems in Multiplex FISH

    • Jon C. Strefford
    Pages 235-243

  18. Some Difficult Choices in Cytogenetics

    • John Swansbury
    Pages 245-257

  19. Introduction to the Analysis of the Human G-Banded Karyotype

    • John Swansbury
    Pages 259-269

  20. Back Matter

    Pages 271-283
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About this book

A collection of key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies. The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias towards anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH.

Reviews

"Eminently practical for every stage of diagnostic service, this book offers laboratories a user-friendly collection of standard and advanced techniques, carefully designed to improve diagnosis and clinical management of cancer patients." - Clinical Laboratory International

"...an immensely useful book for anyone working in the field of cytogenetics. The author has filled this volume with the sort of detail that enables ready translation of methods into practice and provides clear explanations of individual steps within procedures..." - Cancer Forum

Editors and Affiliations

  • The Royal Marsden NHS Trust, The Institute of Cancer Research, Sutton, UK

    John Swansbury

Bibliographic Information

  • Book Title: Cancer Cytogenetics

  • Book Subtitle: Methods and Protocols

  • Editors: John Swansbury

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1385/1592593631

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2003

  • eBook ISBN: 978-1-59259-363-7Published: 05 February 2008

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 284

  • Topics: Human Genetics

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