Abstract
Transcripts of each of the four NF1 genes (NF1 A, B, C (CTF/NF1) and X) are expressed in both lactating and involuting mouse mammary gland but there is an indication that increased expression of an NF1 C (CTF/NF1) transcript accompanies early involution. The involution-associated 74 kD NF1 and the 114 kD lactation-associated NF1 are recognised by an anti-NF1 C-specific antibody that does not cross-react with other NF1 proteins. It is most likely that this lactation/involution switch in NF1 factors represents a change in expression of NF1 C (CTF/NF1) proteins.
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© 2002 Kluwer Academic Publishers
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Kane, R., Finlay, D., Lamb, T., Martin, F. (2002). Transcription Factor NF 1 Expression in Involuting Mammary Gland. In: Mol, J.A., Clegg, R.A. (eds) Biology of the Mammary Gland. Advances in Experimental Medicine and Biology, vol 480. Springer, Boston, MA. https://doi.org/10.1007/0-306-46832-8_14
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DOI: https://doi.org/10.1007/0-306-46832-8_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-306-46414-0
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