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Antipsychotics in acute mania

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Bipolar Disorders

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References

  • American Psychiatric Association. Practice Guideline for the Treatment of Patients with Bipolar Disorder. Am J Psychiatry. 1994;151(Dec. Suppl.).

    Google Scholar 

  • Baastrup PC, Ahlfors UG, Bjerkenstedt et al. A controlled Nordic multicentre study of zuclopenthixol acetate in oil solution, haloperidol and zuclopenthixol in the treatment of acute psychosis. Acta Psychiatr Scand. 1993;87:48–58.

    PubMed  CAS  Google Scholar 

  • Banov MD, Zarate CA Jr, Tohen M et al. Clozapine therapy in refractory affective disorders: polarity predicts response in long-term follow-up. J Clin Psychiatry. 1994;55:295–300.

    PubMed  CAS  Google Scholar 

  • Barbini B, Scherillo P, Benedetti F, Crespi G, Colombo C, Smeraldi E. Response to clozapine in acute mania is more rapid than that of chlorpromazine. Int Clin Psychopharmacol. 1997;12:109–12.

    PubMed  CAS  Google Scholar 

  • Battegay R, Cotar B, Fleischhauer J et al. Results and side effects of treatment with clozapine (Leponex). Compr Psychiatry. 1977;18:423–8.

    Article  PubMed  CAS  Google Scholar 

  • Calabrese JR, Meltzer HY, Markovitz PJ. Clozapine prophylaxis in rapid cycling bipolar disorder. J Clin Psychopharmacol. 1991;6:396–7.

    Google Scholar 

  • Calabrese JR, Kimmel SE, Woyshville MJ et al. Clozapine in mania. Proceedings of the 32nd Annual Meeting of the American College of Neuropsychopharmacology; December 1993; Oahu, Hawaii, p. 150.

    Google Scholar 

  • Calabrese JR, Kimmel SE, Woyshville MJ et al. Clozapine for treatment-refractory mania. Am J Psychiatry. 1996;153:759–64.

    PubMed  CAS  Google Scholar 

  • Chacko RC, Hurley RA, Jankovic J. Clozapine use in diffuse Lewy Body disease. J Neuropsychiatry Clin Neurosci. 1993;5:206–8.

    PubMed  CAS  Google Scholar 

  • Chakos MH, Alvir JM, Woerner MG et al. Incidence and correlates of tardive dyskinesia in first episode of schizophrenia. Arch Gen Psychiatry. 1996;53:313–19.

    PubMed  CAS  Google Scholar 

  • Chou JCY, Zito JM, Vitrai J, Craig TJ, Allingham BH, Czobor P. Neuroleptics in acute mania: a pharmacoepidemiological study. Pharmacoepidemiology. 1996;30: 1396–8.

    CAS  Google Scholar 

  • Cole JO, Banov MD, Green A et al. Clozapine in the treatment of refractory acute mania. In: New Research Program and Abstracts of the 146th Annual Meeting of the American Psychiatric Association; 26 May 1993; San Francisco, Calif. Abstract NR455:174.

    Google Scholar 

  • Cooper, JE, Kendell RE, Gurland BJ et al. Psychiatric Diagnosis in New York and London: a Comparative Study of Mental Hospital Admissions. Institute of Psychiatry, Maudsley Monographs 20. London: Oxford University Press; 1972.

    Google Scholar 

  • Cookson JC, Silverstone T, Wells B. A double-blind controlled study of pimozide vs. chlorpromazine in mania. Neuropharmacology. 1979;18:1011–13.

    Article  PubMed  CAS  Google Scholar 

  • Cookson JC, Silverstone T, Wells B. Double-blind comparative trial of pimozide and chlorpromazine in mania. A test of the dopamine hypothesis. Acta Psychiatr Scand. 1981;64:381–97.

    PubMed  CAS  Google Scholar 

  • Dassa D, Kaladjian A, Azorin JM et al. Clozapine in the treatment of psychotic refractory depression. Br J Psychiatry. 1993;163:822–4.

    PubMed  CAS  Google Scholar 

  • Delay J, Deniker P, Harl J. Utilization therapeutique psychiatrique ďune phenothiazine ďaction cetrale elective (4560 RP). Ann Med Psychol. 1952;110:112–17.

    CAS  Google Scholar 

  • Faltus F, Hynek K, Dolezalova V et al. Experience in the treatment of schizophrenia with clozapine (letter). Activ Nerv Super (Prague). 1973;15:95.

    CAS  Google Scholar 

  • Frankenburg FR. Clozapine in bipolar disorder. J Clin Psychopharmacol. 1993;13:289–90.

    Google Scholar 

  • Gaertner HJ, Fischer E, Hoss J. Side effects of clozapine. Psychopharmacology (Berl). 1989;99:S97–100.

    Google Scholar 

  • Garfinkel PE, Stancer HC, Persad E. A comparison of haloperidol, lithium carbonate and their combination in the treatment of mania. J Affect Disord. 1980;2:279–88.

    Article  PubMed  CAS  Google Scholar 

  • Glazer WM, Morgenstern H. Predictors of occurrence, severity, and course of tardive dyskinesia in an outpatient population (Review; 37 refs). J Clin Psychopharmacol. 1988;9(4 Suppl.):10–16S.

    Google Scholar 

  • Goodnick PJ. Risperidone treatment of refractory acute mania (letter). J Clin Psychiatry. 1995;56:431–2.

    PubMed  CAS  Google Scholar 

  • Gouliaev G, Licht RW, Vestergaard P, Merinder L, Lund H, Bjerre L. Treatment of manic episodes: zuclopenthixol and clonazepam versus lithium and clonazepam. Acta Psychiatr Scand. 1996, 93:119–24.

    PubMed  CAS  Google Scholar 

  • Hillert A, Maier W, Wetzel H et al. Risperidone in the treatment of disorders with a combined psychotic and depressive syndrome: a functional approach. Pharmacopsychiatry. 1992;25:213–17.

    PubMed  CAS  Google Scholar 

  • Jacobsen FM. Risperidone in the treatment of affective illness and obsessive-compulsive disorder. J Clin Psychiatry. 1995;56:423–9.

    PubMed  CAS  Google Scholar 

  • Janicak PG, Bresnahan DB, Sharma R, Davis JM, Comaty JE, Malinick C. A comparison of thiothixene with chlorpromazine in the treatment of mania. J Clin Psychopharmacol. 1988;8:33–7.

    PubMed  CAS  Google Scholar 

  • Jeste DV, Caligiuri MP, Paulsen JS et al. Risk of tardive dyskinesia in older patients. A prospective longitudinal study of 266 outpatients. Arch Gen Psychiatry. 1995;52:756–65.

    PubMed  CAS  Google Scholar 

  • Juul Povlsen J, Noring U, Fog R et al. Tolerability and therapeutic effect of clozapine. Acta Psychiatr Scand. 1985;71:176–85.

    PubMed  CAS  Google Scholar 

  • Kane JM. The role of neuroleptics in manic-depressive illness. J Clin Psychiatry. 1988;49(11. Suppl.):12–13.

    PubMed  Google Scholar 

  • Kane JM, Smith JM. Tardive dyskinesia: prevalence and risk factors. Arch Gen Psychiatry. 1982;39:473–81.

    PubMed  CAS  Google Scholar 

  • Keck PE Jr, Wilson DR, Strakowski SM et al. Clinical predictors of acute risperidone response in schizophrenia, schizoaffective disorder, and psychotic mood disorders. J Clin Psychiatry. 1995;56:466–70.

    PubMed  Google Scholar 

  • Kimmel SE, Calabrese JR, Meltzer HY. Clozapine in treatment refractory mania. In: 1993 CME Syllabus and Proceedings Summary of the Annual Meeting of the American Psychiatric Association; 24 May 1993; San Francisco, Calif. Abstract 21:80.

    Google Scholar 

  • Klein DF. Importance of psychiatric diagnosis in prediction of clinical drug effects. Arch Gen Psychiatry. 1967;16:118–26.

    PubMed  CAS  Google Scholar 

  • Kukopulos A, Reginaldi D, Laddomada P et al. Course of the manic-depressive cycle and changes caused by treatment. Pharmakopsychiatrie-Neuropsychopharakol. 1980;13:156–67.

    CAS  Google Scholar 

  • Leppig M, Bosch B, Naber D et al. Clozapine in the treatment of 12 out-patients. Psychopharmacology (Berl). 1989;99:S77–9.

    Google Scholar 

  • Lindstrom LH. A retrospective study on the long-term efficacy of clozapine in 96 schizophrenic and schizoaffective patients during a 13-year period. Psychopharmacology (Berl). 1989;99:S84–6.

    Google Scholar 

  • McElroy SL, Dessain EC, Pope HG Jr et al. Clozapine in the treatment of psychotic mood disorders, schizoaffective disorder, and schizophrenia. J Clin Psychiatry. 1991;52:411–14.

    PubMed  CAS  Google Scholar 

  • McElroy SL, Keck PE Jr, Stanton SP et al. A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania. J Clin Psychiatry. 1996;57:142–6.

    PubMed  CAS  Google Scholar 

  • McElroy SL, Frye MA, Denikoff KD et al. Olanzapine in treatment-resistant bipolar disorder. J Affect Disord. 1998;49:19–22.

    Article  Google Scholar 

  • Morgenstern H, Glazer WM. Identifying risk factors for tardive dyskinesia among long-term outpatients maintained with neuroleptic medications. Results of the Yale Tardive Dyskinesia Study. Arch Gen Psychiatry. 1993;50:723–33.

    PubMed  CAS  Google Scholar 

  • Naber D, Leppig M, Grohmann R et al. Efficacy and adverse effects with clozapine in the treatment of schizophrenia and tardive dyskinesia: a retrospective study of 387 patients. Psychopharmacology (Berl). 1989;99:S73–6.

    Google Scholar 

  • Naber D, Hippius H. The European experience with use of clozapine. Hosp Community Psychiatry. 1990;41:886–90.

    PubMed  CAS  Google Scholar 

  • Naber D, Hozbach R, Perro C et al. Clinical management of clozapine patients in relation to efficacy and side-effects. Br J Psychiatry. 1992;160:54–9.

    Google Scholar 

  • Nasarallah HA, Churchill CM, Hamdan-Allan GA. Higher frequency of neuroleptic-induced dystonia in mania than in schizophrenia. Am J Psychiatry. 1988; 145:1455–6.

    Google Scholar 

  • Owen RR, Beake B, Marby D et al. Response to clozapine in chronic psychotic patients. Psychopharmacol Bull. 1989;25:253–6.

    PubMed  Google Scholar 

  • Parsa MA, Ramirez LF, Loula CE et al. Effect of clozapine on psychotic depression and Parkinsonism. J Clin Psychopharmacol. 1991;11:330–1.

    PubMed  CAS  Google Scholar 

  • Pickar D, Owen RR, Litman RE et al. Clinical and biologic response to clozapine in patients with schizophrenia. Arch Gen Psychiatry. 1992a;49:345–53.

    PubMed  CAS  Google Scholar 

  • Pickar D, Owen RR, Litman RE et al. Clinical and biologic response to clozapine in patients with schizophrenia. Arch Gen Psychiatry. 1992b;49:345–53.

    PubMed  CAS  Google Scholar 

  • Platman SR. A comparison of lithium carbonate and chlorpromazine in mania. Am J Psychiatry. 1970;127:127–9.

    Google Scholar 

  • Prien RF, Caffey EM Jr, Klett CJ. Comparison of lithium carbonate and chlorpromazine in the treatment of mania. Arch Gen Psychiatry. 1972;26:146–53.

    PubMed  CAS  Google Scholar 

  • Privitera MR, Lamberti JS, Maharaj K. Clozapine in a bipolar depressed patient (letter). Am J Psychiatry. 1993;150:986.

    PubMed  CAS  Google Scholar 

  • Rifkin A, Doddi S, Karajgi B, Borenstein M, Munne R. Dosage of haloperidol for mania. Br J Psychiatry. 1994;165:113–16.

    PubMed  CAS  Google Scholar 

  • Rodova A, Suestka J, Nanhunek K et al. A blind comparison of clozapine and perphenazine in schizophrenics. Activ Nerv Super (Prague). 1973;94–5.

    Google Scholar 

  • Sajatovic M, Verbanac P, Ramirez LF et al. Clozapine treatment of psychiatric symptoms resistant to neuroleptic treatment in patients with Huntington’s chorea (letter). Neurology. 1991;41:156.

    PubMed  CAS  Google Scholar 

  • Segal J, Berk M, Brook S. Risperidone compared with both lithium and haloperidol in mania: a double-blind randomized controlled trial. Clinical Neuropharmacol. 1998;21:176–80.

    CAS  Google Scholar 

  • Shopsin B, Gershon S, Thompson H, Collins P. Psychoactive drugs in mania. A controlled comparison of lithium carbonate, chlorpromazine, and haloperidol. Arch Gen Psychiatry. 1975;32:34–42.

    PubMed  CAS  Google Scholar 

  • Singh AN, Catalan J. Risperidone in HIV-related manic psychosis. Lancet. 1994;344:1029–30.

    PubMed  CAS  Google Scholar 

  • Small JG, Milstein V, Marhenke JD et al. Treatment outcome with clozapine in tardive dyskinesia, neuroleptic sensitivity, and treatment-resistant psychosis. J Clin Psychiatry. 1987;48:263–7.

    PubMed  CAS  Google Scholar 

  • Suppes T, McElroy SL, Gilbert J et al. Clozapine in the treatment of dysphoric mania. Biol Psychiatry. 1992;32:270–80.

    Article  PubMed  CAS  Google Scholar 

  • Suppes T, Phillips KA, Judd CR. Clozapine treatment of non-psychotic rapid cycling bipolar disorder: a report of three cases. Biol Psychiatry. 1994;36:338–40.

    Article  PubMed  CAS  Google Scholar 

  • Suppes T, Webb A, Paul B, Carmody T, Kraemer H, Rush AJ. Clinical outcome in a randomized 1-year trial of clozapine versus treatment as usual for patients with treatment-resistant illness and a history of mania. Am J Psychiatry. 1999;56:1164–9.

    Google Scholar 

  • Takahashi R, Sakuma A, Itoh H, Kurihara M, Saito M, Watanabe M. Comparison of efficacy of lithium carbonate and chlorpromazine in mania. Arch Gen Psychiatry. 1975;32:1310–18.

    PubMed  CAS  Google Scholar 

  • Tohen M, Zarate CA Jr. Antipsychotic agents and bipolar disorder. J Clin Psychiatry. 1998;59:38–48.

    PubMed  CAS  Google Scholar 

  • Tohen M, Zarate CA Jr, Centorrino F et al. Risperidone in the treatment of mania. J Clin Psychiatry. 1996;57:6:249–53.

    PubMed  CAS  Google Scholar 

  • Tohen M, Zhang F, Taylor C et al. A meta-analysis of the use of typical antipsychotics in bipolar disorders. J Affect Disord. 2000;69:l-9.

    Google Scholar 

  • Tohen M, Sanger TM, McElroy SL et al. Olanzapine versus placebo in the treatment of acute mania. Am J Psychiatry. 1999a;156:5:702–9.

    PubMed  CAS  Google Scholar 

  • Tohen M, Jacobs T, Grundy S et al. Efficacy of olanzapine in acute bipolar mania. A double-blind placebo controlled study. Arch Gen Psychiatry. 2000;57:841–9.

    PubMed  CAS  Google Scholar 

  • Tran PV, Hamilton SH, Kuntz AJ et al. Double-blind comparison of olanzapine versus risperidone in the treatment of schizophrenia and other psychotic disorders. J Clin Psychopharmacol. 1997;17:407–18.

    Article  PubMed  CAS  Google Scholar 

  • Van Praag HM, Korf J, Dols LCW. Clozapine versus perphenazine. Br J Psychiatry. 1976;129:547–55.

    PubMed  Google Scholar 

  • Wood MJ, Rubinstein M. An atypical responder to clozapine (letter). Am J Psychiatry. 1990;147:369.

    PubMed  CAS  Google Scholar 

  • Zarate CA Jr, Tohen M, Baldessarini MD. Clozapine in severe mood disorders. J Clin Psychiatry. 1995a;56:9:411–16.

    PubMed  Google Scholar 

  • Zarate CA Jr, Tohen M, Banov MD et al. Is clozapine monotherapy a mood stabilizer? J Clin Psychiatry. 1995b;56:109–13.

    Google Scholar 

  • Zarate CA Jr, Narendran R, Tohen M et al. Clinical predictors of acute response with olanzapine in psychotic mood disorders. J Clin Psychiatry. 1997;59:24–8.

    Google Scholar 

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Authors
  1. Mauricio Tohen
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Editors and Affiliations

  1. Martin-Luther-University Halle-Wittenberg, Halle, Germany

    Andreas Marneros

  2. University Zürich, Zürich, Switzerland

    Jules Angst

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© 2000 Kluwer Academic Publishers

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Tohen, M. (2000). Antipsychotics in acute mania. In: Marneros, A., Angst, J. (eds) Bipolar Disorders. Springer, Dordrecht. https://doi.org/10.1007/0-306-47521-9_18

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  • DOI: https://doi.org/10.1007/0-306-47521-9_18

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-7923-6588-4

  • Online ISBN: 978-0-306-47521-4

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