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Inositol Phosphates and Phosphoinositides in Health and Disease

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Biology of Inositols and Phosphoinositides

Part of the book series: Subcellular Biochemistry ((SCBI,volume 39))

4. Summary

In the past two decades, considerable progress has been made toward understanding inositol phosphates and PI metabolism. However, there is still much to learn. The present challenge is to understand how inositol phosphates and PIs are compartmentalized, identify new targets of inositol phosphates and PIs, and elucidate the mechanisms underlying spatial and temporal regulation of the enzymes that metabolize inositol phosphates and PIs. Answers to these questions will help clarify the mechanisms of the diseases associated with these molecules and identify new possibilities for drug design.

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  1. Department of Biological Sciences, Wayne State University, Detroit, MI, 8202, USA

    Yihui Shi, Abed N. Azab, Morgan N. Thompson & Miriam L. Greenberg

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  1. Bose Institute, Kolkata, India

    A. Lahiri Majumder

  2. University College of Science, Kolkata, India

    B. B. Biswas

  3. University of Calcutta, Kolkata, India

    B. B. Biswas

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Shi, Y., Azab, A.N., Thompson, M.N., Greenberg, M.L. (2006). Inositol Phosphates and Phosphoinositides in Health and Disease. In: Majumder, A.L., Biswas, B.B. (eds) Biology of Inositols and Phosphoinositides. Subcellular Biochemistry, vol 39. Springer, Boston, MA . https://doi.org/10.1007/0-387-27600-9_11

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