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Genetic Granular Kernel Methods for Cyclooxygenase-2 Inhibitor Activity Comparison

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Advances in Neural Networks - ISNN 2006 (ISNN 2006)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 3971))

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Abstract

How to design powerful and flexible kernels to improve the system performance is an important topic in kernel based classification. In this paper, we present a new granular kernel method to improve the performance of Support Vector Machines (SVMs). In the system, genetic algorithms (GAs) are used to generate feature granules and optimize them together with fusions and parameters of granular kernels. The new granular kernel method is used for cyclooxygenase-2 inhibitor activity comparison. Experimental results show that the new method can achieve better performance than SVMs with traditional RBF kernels in terms of prediction accuracy.

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© 2006 Springer-Verlag Berlin Heidelberg

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Jin, B., Zhang, YQ. (2006). Genetic Granular Kernel Methods for Cyclooxygenase-2 Inhibitor Activity Comparison. In: Wang, J., Yi, Z., Zurada, J.M., Lu, BL., Yin, H. (eds) Advances in Neural Networks - ISNN 2006. ISNN 2006. Lecture Notes in Computer Science, vol 3971. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11759966_135

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  • DOI: https://doi.org/10.1007/11759966_135

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-34439-1

  • Online ISBN: 978-3-540-34440-7

  • eBook Packages: Computer ScienceComputer Science (R0)

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