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Non-Skull Base Head and Neck Cancer

  • Chapter
Stereotactic Body Radiation Therapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

The standard treatment for non-skull base head and neck cancer is surgery, radiation therapy, chemotherapy, or various combinations of the above. Treatment options are often limited in patients with recurrence after radiation therapy. Although reirradiation can be offered there is an increased risk of serious complications. Stereotactic body radiation therapy (SBRT) has been used as a boost or salvage therapy for head and neck cancer in the skull base, such as nasopharyngeal carcinoma, with promising results. The use of stereotactic body radiation therapy for head and neck cancer in sites outside of the base of skull region is emerging. This chapter review will highlight the technical and clinical advances in SBRT for non-skull base head and neck cancer.

Authors’ Contributions

FS, DB, SY, JL and MY made substantial contributions to the conception, design, drafting, and writing of this book chapter. This book chapter has been seen, read, and agreed upon in its content by all the designated authors.

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References

  • Adelstein DJ, Li Y, Adams GL, Wagner H Jr, Kish JA, Ensley JF, Schuller DE, Forastiere AA (2003) An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol 21(1):92–98

    Article  PubMed  Google Scholar 

  • Adler JR, Jr., Chang SD, Murphy MJ, Doty J, Geis P, Hancock SL (1997) The Cyberknife: a frameless robotic system for radiosurgery. Stereotact Funct Neurosurg 69(1–4 Pt 2):124–128

    Google Scholar 

  • Ali I, Tubbs J, Hibbitts K, Algan O, Thompson S, Herman T, Ahmad S (2010) Evaluation of the setup accuracy of a stereotactic radiotherapy head immobilization mask system using kV on-board imaging. J Appl Clin Med Phys 11(3):3192

    PubMed  Google Scholar 

  • Bernier J, Domenge C, Ozsahin M, Matuszewska K, Lefebvre JL, Greiner RH, Giralt J, Maingon P, Rolland F, Bolla M, Cognetti F, Bourhis J, Kirkpatrick Avan Glabbeke M (2004) Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med 350(19):1945–1952

    Google Scholar 

  • Berson AM, Stein NF, Riegel AC, Destian S, Ng T, Tena LB, Mitnick RJ, Heiba S (2009) Variability of gross tumor volume delineation in head-and-neck cancer using PET/CT fusion, Part II: the impact of a contouring protocol. Med Dosim 34(1):30–35

    Google Scholar 

  • Bonner JA, Harari PM, Giralt J, Azarnia N, Shin DM, Cohen RB, Jones CU, Sur R, Raben D, Jassem J, Ove R, Kies MS, Baselga J, Youssoufian H, Amellal N, Rowinsky EK, Ang KK (2006) Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354(6):567–578

    Article  PubMed  CAS  Google Scholar 

  • Bradley JA, Paulson ES, Ahunbay E, Schultz C, Li XA, Wang D (2011) Dynamic MRI analysis of tumor and organ motion during rest and deglutition and margin assessment for radiotherapy of head-and-neck cancer. Int J Radiat Oncol Biol Phys (in press)

    Google Scholar 

  • Brenner DJ (2008) The linear-quadratic model is an appropriate methodology for determining isoeffective doses at large doses per fraction. Semin Radiat Oncol 18(4):234–239

    Article  PubMed  Google Scholar 

  • Calais G, Alfonsi M, Bardet E, Sire C, Germain T, Bergerot P, Rhein B, Tortochaux J, Oudinot P, Bertrand P (1999) Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst 91(24):2081–2086

    Article  PubMed  CAS  Google Scholar 

  • Cengiz M, Ozyigit G, Yazici G, Dogan A, Yildiz F, Zorlu F, Gurkaynak M, Gullu IH, Hosal SA, kyol F (2010) Salvage reirradiaton with stereotactic body radiotherapy for locally recurrent head-and-neck tumors. Int J Radiat Oncol Biol Phys

    Google Scholar 

  • Cooper JS, Pajak TF, Forastiere AA, Jacobs J, Campbell BH, Saxman SB, Kish JA, Kim HE, Cmelak AJ, Rotman M, Machtay M, Ensley JF, Chao KS, Schultz CJ, Lee N, Fu KK (2004) Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 350(19):1937–1944

    Article  PubMed  Google Scholar 

  • Daisne JF, Duprez T, Weynand B, Lonneux M, Hamoir M, Reychler H, Gregoire V (2004) Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen. Radiology 233(1):93–100

    Article  PubMed  Google Scholar 

  • Dandekar P, Partridge M, Kazi R, Nutting C, Harrington K, Newbold K (2010) Challenges in integrating 18FDG PET-CT into radiotherapy planning of head and neck cancer. Indian J Cancer 47(3):260–266

    Article  PubMed  CAS  Google Scholar 

  • De Crevoisier R, Bourhis J, Domenge C, Wibault P, Koscielny S, Lusinchi A, Mamelle G, Janot F, Julieron M, Leridant AM, Marandas P, Armand JP, Schwaab G, Luboinski BE, Schwege F (1998) Full-dose reirradiation for unresectable head and neck carcinoma: experience at the Gustave-Roussy Institute in a series of 169 patients. J Clin Oncol 16(11):3556–3562

    PubMed  Google Scholar 

  • De Crevoisier R, Domenge C, Wibault P, Koscielny S, Lusinchi A, Janot F, Bobin S, Luboinski B, Eschwege F, Bourhis J (2001) Full dose reirradiation combined with chemotherapy after salvage surgery in head and neck carcinoma. Cancer 91(11):2071–2076

    Article  PubMed  Google Scholar 

  • Droege RT, Bjarngard BE (1979a) Metal screen-film detector MTF at megavoltage X-ray energies. Med Phys 6(6):515–518

    Article  CAS  Google Scholar 

  • Droege RT, Bjarngard BE (1979b) Influence of metal screens on contrast in megavoltage X-ray imaging. Med Phys 6(6):487–493

    Article  CAS  Google Scholar 

  • Duprez F, Madani I, Bonte K, Boterberg T, Vakaet L, Derie C, De Gersem W, De Neve W (2009) Intensity-modulated radiotherapy for recurrent and second primary head and neck cancer in previously irradiated territory. Radiother Oncol 93(3):563–569

    Article  PubMed  Google Scholar 

  • Feldkamp IA, Davis LC, Kress JW (1984) Practical cone-beam algorithm. J Opt Soc Am A 1(6):612–619

    Article  Google Scholar 

  • Fu KK, Pajak TF, Trotti A, Jones CU, Spencer SA, Phillips TL, Garden AS, Ridge JA, Cooper JS, Ang KK (2000) A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003. Int J Radiat Oncol Biol Phys 48(1):7–16

    Google Scholar 

  • Fuks Z, Kolesnick R (2005) Engaging the vascular component of the tumor response. Cancer Cell 8(2):89–91

    Article  PubMed  CAS  Google Scholar 

  • Garcia-Barros M, Paris F, Cordon-Cardo C, Lyden D, Rafii S, Haimovitz-Friedman A, Fuks Z, Kolesnick R (2003) Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 300(5622):1155–1159

    Article  PubMed  CAS  Google Scholar 

  • Heron DE (2009) Stereotactic body radiation therapy for recurrent head & neck cancers: rethinking nonoperative salvage strategies. Future Oncol 5(9):1321–1325

    Article  PubMed  Google Scholar 

  • Heron DE, Rwigema JC, Gibson MK, Burton SA, Quinn AE, Ferris RL (2010) Concurrent cetuximab with stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: a single institution matched case-control study. Am J Clin Oncol 34(2):165–172

    Google Scholar 

  • Heron DE, Rwigema JC, Gibson MK, Burton SA, Quinn A, Ferris RL (2011) Concurrent cetuximab with stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: a single institution matched case-control study. Am J Clin Oncol 34(2):165–172

    PubMed  CAS  Google Scholar 

  • Hong LX, Chen CC, Garg M, Yaparpalvi R, Mah D (2009) Clinical experiences with onboard imager KV images for linear accelerator-based stereotactic radiosurgery and radiotherapy setup. Int J Radiat Oncol Biol Phys 73(2):556–561

    Article  PubMed  Google Scholar 

  • Jaffray DA, Siewerdsen JH, Wong Martinez JW, Martinez AA (2002) Flat-panel cone-beam computed tomography for image-guided radiation therapy. Int J Radiat Oncol Biol Phys 53(5):1337–1349

    Article  PubMed  Google Scholar 

  • Janot F, de Raucourt D, Benhamou E, Ferron C, Dolivet G, Bensadoun RJ, Hamoir M, Gery B, Julieron M, Castaing M, Bardet E, Gregoire V, Bourhis J (2008) Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma. J Clin Oncol 26(34):5518–5523

    Article  PubMed  CAS  Google Scholar 

  • Jin JY, Ryu S, Faber K, Mikkelsen T, Chen Q, Li S, Movsas B (2006) 2D/3D image fusion for accurate target localization and evaluation of a mask based stereotactic system in fractionated stereotactic radiotherapy of cranial lesions. Med Phys 33(12):4557–4566

    Article  PubMed  Google Scholar 

  • Kasperts N, Slotman B, Leemans CR, Langendijk JA (2005) A review on re-irradiation for recurrent and second primary head and neck cancer. Oral Oncol 41(3):225–243

    Article  PubMed  CAS  Google Scholar 

  • Kawaguchi K, Sato K, Horie A, Iketani S, Yamada H, Nakatani Y, Sato J, Hamada Y (2010) Stereotactic radiosurgery may contribute to overall survival for patients with recurrent head and neck carcinoma. Radiat Oncol 5:51

    Article  PubMed  Google Scholar 

  • Kirkpatrick JP, Meyer JJ, Marks LB (2008) The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery. Semin Radiat Oncol 18(4):240–243

    Article  PubMed  Google Scholar 

  • Kodani N, Yamazaki H, Tsubokura T, Shiomi H, Kobayashi K, Nishimura T, Aibe N, Ikeno H (2010) Stereotactic body radiation therapy for head and neck tumor: disease control and morbidity outcomes. J Radiat Res (Tokyo)

    Google Scholar 

  • Kodani N, Yamazaki H, Tsubokura T, Shiomi H, Kobayashi K, Nishimura T, Aibe N, Ikeno H (2011) Stereotactic body radiation therapy for head and neck tumor: disease control and morbidity outcomes. J Radiat Res (Tokyo) 52(1):24–31

    Article  Google Scholar 

  • Kolotas C, Tselis N, Sommerlad M, Roddiger S, Schnabel T, Baltas D, Kalogera-Fountzila A, Fountzilas G, Zamboglou N (2007) Reirradiation for recurrent neck metastases of head-and-neck tumors using CT-guided interstitial 192Ir HDR brachytherapy. Strahlenther Onkol 183(2):69–75

    Article  PubMed  Google Scholar 

  • Langendijk JA, Bourhis J (2007) Reirradiation in squamous cell head and neck cancer: recent developments and future directions. Curr Opin Oncol 19(3):202–209

    Article  PubMed  Google Scholar 

  • Langer CJ, Harris J, Horwitz EM, Nicolaou N, Kies M, Curran W, Wong S, Ang K (2007) Phase II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-daily reirradiation in recurrent squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Protocol 9911. J Clin Oncol 25(30):4800–4805

    Google Scholar 

  • Lee N, Chan K, Bekelman JE, Zhung J, Mechalakos J, Narayana A, Wolden S, Venkatraman ES, Pfister D, Kraus D, Shah J, Zelefsky MJ (2007) Salvage re-irradiation for recurrent head and neck cancer. Int J Radiat Oncol Biol Phys 68(3):731–740

    Article  PubMed  Google Scholar 

  • Leksell L (1951) The stereotaxic method and radiosurgery of the brain. Acta Chir Scand 102(4):316–319

    PubMed  CAS  Google Scholar 

  • Leksell L, Lindquist C, Adler JR, Leksell D, Jernberg B, Steiner L (1987) A new fixation device for the Leksell stereotaxic system. Technical note. J Neurosurg 66(4):626–629

    CAS  Google Scholar 

  • Lo SS, Dawson LA, Kim EY, Mayr NA, Wang JZ, Huang Z, Cardenes HR (2010a) Stereotactic body radiation therapy for hepatocellular carcinoma. Discov Med 9(48):404–410

    Google Scholar 

  • Lo SS, Fakiris AJ, Chang EL, Mayr NA, Wang JZ, Papiez L, Teh BS, McGarry RC, Cardenes HR, Timmermann RD (2010b) Stereotactic body radiation therapy: a novel treatment modality. Nat Rev Clin Oncol 7(1):44–54

    Article  Google Scholar 

  • Lo SS, Sahgal A, Wang JZ, Mayr NA, Sloan A, Mendel E, Chang EL (2010c) Stereotactic body radiation therapy for spinal metastases. Discov Med 9(47):289–296

    Google Scholar 

  • Lo SS, Teh BS, Mayr NA, Olencki TE, Wang JZ, Grecula JC, Lu JJ, Timmerman RD (2010d) Stereotactic body radiation therapy for oligometastases. Discov Med 10(52):247–254

    Google Scholar 

  • Lu TX, Mai WY, Teh BS, Zhao C, Han F, Huang Y, Deng XW, Lu LX, Huang SM, Zeng ZF, Lin CG, Lu HH, Chiu JK, Carpenter LS, Grant WH 3rd, Woo SY, Cui NJ, Butler EB (2004) Initial experience using intensity-modulated radiotherapy for recurrent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 58(3):682–687

    Article  PubMed  Google Scholar 

  • Mackie TR, Holmes T, Swerdloff S, Reckwerdt P, Deasy JO, Yang J, Paliwal B, Kinsella T (1993) Tomotherapy: a new concept for the delivery of dynamic conformal radiotherapy. Med Phys 20(6):1709–1719

    Article  PubMed  CAS  Google Scholar 

  • McDonald MW, Moore MG, Johnstone PA (2011) Risk of carotid blowout after reirradiation of the head and neck: a systematic review. Int J Radiat Oncol Biol Phys (in press)

    Google Scholar 

  • Moore CS, Liney GP, Beavis AW (2004) Quality assurance of registration of CT and MRI data sets for treatment planning of radiotherapy for head and neck cancers. J Appl Clin Med Phys 5(1):25–35

    Article  PubMed  Google Scholar 

  • Morin O, Gillis A, Chen J, Aubin M, Bucci MK, Roach M, 3rdPouliot J (2006) Megavoltage cone-beam CT: system description and clinical applications. Med Dosim 31(1):51–61

    Google Scholar 

  • Nakamoto Y, Tamai K, Saga T, Higashi T, Hara T, Suga T, Koyama T, Togashi K (2009) Clinical value of image fusion from MR and PET in patients with head and neck cancer. Mol Imaging Biol 11(1):46–53

    Article  PubMed  Google Scholar 

  • Park C, Papiez L, Zhang S, Story M, Timmerman RD (2008) Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy. Int J Radiat Oncol Biol Phys 70(3):847–852

    Article  PubMed  Google Scholar 

  • Pignon JP, le Maitre A, Maillard E, Bourhis J (2009) Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17, 346 patients. Radiother Oncol 92(1):4–14

    Article  PubMed  Google Scholar 

  • Popovtzer A, Gluck I, Chepeha DB, Teknos TN, Moyer JS, Prince ME, Bradford CR, Eisbruch A (2009) The pattern of failure after reirradiation of recurrent squamous cell head and neck cancer: implications for defining the targets. Int J Radiat Oncol Biol Phys 74(5):1342–1347

    Article  PubMed  Google Scholar 

  • Prevost JB, de Boer H, Poll J, Voet P, Levendag P (2008) Analysis of the motion of oropharyngeal tumors and consequences in planning target volume determination. Radiother Oncol 87(2):268–273

    Article  PubMed  Google Scholar 

  • Riegel AC, Berson AM, Destian S, Ng T, Tena LB, Mitnick RJ, Wong PS (2006) Variability of gross tumor volume delineation in head-and-neck cancer using CT and PET/CT fusion. Int J Radiat Oncol Biol Phys 65(3):726–732

    Article  PubMed  Google Scholar 

  • Roh KW, Jang JS, Kim MS, Sun DI, Kim BS, Jung SL, Kang JH, Yoo EJ, Yoon SC, Jang HS, Chung SM, Kim YS (2009) Fractionated stereotactic radiotherapy as reirradiation for locally recurrent head and neck cancer. Int J Radiat Oncol Biol Phys 74(5):1348–1355

    Article  PubMed  Google Scholar 

  • Rwigema JC, Heron DE, Ferris RL, Andrade RS, Gibson MK, Yang Y, Ozhasoglu C, Argiris AE, Grandis JR, Burton SA (2010) The impact of tumor volume and radiotherapy dose on outcome in previously irradiated recurrent squamous cell carcinoma of the head and neck treated with stereotactic body radiation therapy. Am J Clin Oncol 34(4):372–379

    Article  Google Scholar 

  • Schinagl DA, Vogel WV, Hoffmann AL, van Dalen JA, Oyen WJ, Kaanders JH (2007) Comparison of five segmentation tools for 18F-fluoro-deoxy-glucose-positron emission tomography-based target volume definition in head and neck cancer. Int J Radiat Oncol Biol Phys 69(4):1282–1289

    Article  PubMed  CAS  Google Scholar 

  • Sher DJ, Haddad RI, Norris CM Jr, Posner MR, Wirth LJ, Goguen LA, Annino D, Balboni T, Allen A, Tishler RB (2010) Efficacy and toxicity of reirradiation using intensity-modulated radiotherapy for recurrent or second primary head and neck cancer. Cancer 116(20):4761–4768

    Article  PubMed  Google Scholar 

  • Siddiqui F, Patel M, Khan M, McLean S, Dragovic J, Jin JY, Movsas B, Ryu S (2009) Stereotactic body radiation therapy for primary, recurrent, and metastatic tumors in the head-and-neck region. Int J Radiat Oncol Biol Phys 74(4):1047–1053

    Article  PubMed  Google Scholar 

  • Siegel R, Ward E, Brawley O, Jemal A (2011) Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61(4):212–236

    Article  PubMed  Google Scholar 

  • Simon E, Fox TH, Lee D, Waller AF, Pantalone P, Jani AB (2009) PET lesion segmentation using automated iso-intensity contouring in head and neck cancer. Technol Cancer Res Treat 8(4):249–255

    PubMed  Google Scholar 

  • Spencer SA, Harris J, Wheeler RH, Machtay M, Schultz C, Spanos W, Rotman M, Meredith R (2001) RTOG 96–10: reirradiation with concurrent hydroxyurea and 5-fluorouracil in patients with squamous cell cancer of the head and neck. Int J Radiat Oncol Biol Phys 51(5):1299–1304

    Article  PubMed  CAS  Google Scholar 

  • Taussky D, Dulguerov P, Allal AS (2005) Salvage surgery after radical accelerated radiotherapy with concomitant boost technique for head and neck carcinomas. Head Neck 27(3):182–186

    Article  PubMed  Google Scholar 

  • Temam S, Pape E, Janot F, Wibault P, Julieron M, Lusinchi A, Mamelle G, Marandas P, Luboinski B, Bourhis J (2005) Salvage surgery after failure of very accelerated radiotherapy in advanced head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys 62(4):1078–1083

    Article  PubMed  Google Scholar 

  • Troost EG, Schinagl DA, Bussink J, Boerman OC, van der Kogel AJ, Oyen WJ, Kaanders JH (2010) Innovations in radiotherapy planning of head and neck cancers: role of PET. J Nucl Med 51(1):66–76

    Article  PubMed  Google Scholar 

  • Unger KR, Lominska CE, Deeken JF, Davidson BJ, Newkirk KA, Gagnon GJ, Hwang J, Slack RS, Noone AM, Harter KW (2010) Fractionated stereotactic radiosurgery for reirradiation of head-and-neck cancer. Int J Radiat Oncol Biol Phys 77(5):1411–1419

    Article  PubMed  Google Scholar 

  • van Asselen B, Raaijmakers CP, Lagendijk JJ, Terhaard CH (2003) Intrafraction motions of the larynx during radiotherapy. Int J Radiat Oncol Biol Phys 56(2):384–390

    Article  PubMed  Google Scholar 

  • Voynov G, Heron DE, Burton S, Grandis J, Quinn A, Ferris R, Ozhasoglu C, Vogel W, Johnson J (2006) Frameless stereotactic radiosurgery for recurrent head and neck carcinoma. Technol Cancer Res Treat 5(5):529–535

    PubMed  Google Scholar 

  • Wadsley JC, Bentzen SM (2004) Investigation of relationship between change in locoregional control and change in overall survival in randomized controlled trials of modified radiotherapy in head-and-neck cancer. Int J Radiat Oncol Biol Phys 60(5):1405–1409

    Article  PubMed  Google Scholar 

  • Wang JZ, Huang Z, Lo SS, Yuh WT, Mayr NA (2010) A generalized linear-quadratic model for radiosurgery, stereotactic body radiation therapy, and high-dose rate brachytherapy. Sci Transl Med 2(39):39–48

    Google Scholar 

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Conflict of Interest

There are no potential conflicts of interest among the authors and this manuscript. There are no financial or non-financial competing interests. This manuscript has been seen, read, and agreed upon in its content by all designated authors. This manuscript has not been submitted or published elsewhere.

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Authors and Affiliations

  1. Department of Radiation Oncology, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI, 48202, USA

    Farzan Siddiqui

  2. Department of Radiation Oncology, University of Colorado Denver, Aurora, CO, 80045, USA

    David Raben

  3. Department of Radiation Oncology, University of California, San Francisco, CA, 94143, USA

    Sue S. Yom

  4. Department of Radiation Oncology, National University Cancer Institute of Singapore, National University of Singapore,  , Singapore

    Jiade J. Lu

  5. Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University, Cleveland, OH, 44106, USA

    Min Yao

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  1. Farzan Siddiqui
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  2. David Raben
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  3. Sue S. Yom
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  4. Jiade J. Lu
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  5. Min Yao
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Correspondence to Farzan Siddiqui .

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Editors and Affiliations

  1. , Department of Radiation Oncology, Case Western Reserve University, Euclid Avenue 11100, Cleveland, 44106, Ohio, USA

    Simon S. Lo

  2. , Department of Radiation Oncology, Weil Cornell Medical College, Fannin, Ste#DB1-077 6565, Houston, 77030, Texas, USA

    Bin S. Teh

  3. Cancer Institute, Department of Radiation Oncology, National University Hospital, Lower Kent Ridge Road 5, Singapore, 119074, Singapore

    Jiade J. Lu

  4. , Department of Radiation Oncology, University of Colorado, Aurora, 80045, Colorado, USA

    Tracey E. Schefter

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Siddiqui, F., Raben, D., Yom, S.S., Lu, J.J., Yao, M. (2011). Non-Skull Base Head and Neck Cancer. In: Lo, S., Teh, B., Lu, J., Schefter, T. (eds) Stereotactic Body Radiation Therapy. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_448

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  • DOI: https://doi.org/10.1007/174_2011_448

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