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Multiple Sclerosis: Other MR Techniques

  • Chapter
MR Imaging in White Matter Diseases of the Brain and Spinal Cord

Part of the book series: Medical Radiology Diagnostic Imaging ((Med Radiol Diagn Imaging))

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Conclusions

The application of modern MRI techniques to the assessment of MS patients has considerably improved our understanding of MS pathophysiology and has provided new objective metrics that might be useful to monitor disease evolution, either in natural history studies or in treatment trials. However, none of the quantitative MR-based techniques considered, taken in isolation, is able to provide a complete picture of the complexity of the MS process and this should call for the definition of aggregates of MR quantities, thought to reflect different aspects of MS pathology, to improve our ability to monitor the disease. At present, longitudinal natural history data collected in large samples of MS patients using structural, metabolic and functional MR techniques are needed to gain additional insight into MS pathobiology and on the actual value of modern MR technologies in the management of MS.

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Authors and Affiliations

  1. Neuroimaging Research Unit, Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy

    Massimo Filippi MD & Maria A. Rocca MD

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  1. Massimo Filippi MD
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  2. Maria A. Rocca MD
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Editors and Affiliations

  1. Neuroimaging Research Unit Department of Neurology Scientific Institute, University Ospedale San Raffaele, Via Olgettina, 60, 20132, Milan, Italy

    Massimo Filippi MD (Director) (Director)

  2. Department of Neurology & Behavioral Sciences, University of Siena, Viale Bracci 2, 53100, Siena, Italy

    Nicola De Stefano MD PhD (Associate Professor) (Associate Professor)

  3. Service de Neuroradiologie Diagnostique et Thérapeutique CHU Bordeaux Pellegrin and Laboratoire de Neurobiologie des Affections de la Myéline, Université Victor Segalen, Bourdeaux 2, 33076, Bordeaux, France

    Vincent Dousset MD, PhD (Professor) (Professor)

  4. Department of Electrical Engineering, United States Naval Academy, Maury Hall 227, Annapolis, MD, 21402-5025, USA

    Joseph C. McGowan PhD (Associate Professor of Electrical Engineering) (Associate Professor of Electrical Engineering)

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© 2005 Springer-Verlag Berlin Heidelberg

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Filippi, M., Rocca, M.A. (2005). Multiple Sclerosis: Other MR Techniques. In: Filippi, M., De Stefano, N., Dousset, V., McGowan, J.C. (eds) MR Imaging in White Matter Diseases of the Brain and Spinal Cord. Medical Radiology Diagnostic Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27644-0_15

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  • DOI: https://doi.org/10.1007/3-540-27644-0_15

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  • Online ISBN: 978-3-540-27644-9

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