Abstract
We infer post-hybridization rearrangements in a hybrid genome, given the gene orders on its chromosomes and some knowledge of the two parent genomes. We study this in two biologically and computationally different contexts, genome fusion and interspecific fertilization. Exact algorithms are furnished for some cases, and a heuristic based on the Hannenhalli-Pevzner theory for another.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Gaut, B.S., Doebley, J.F.: DNA sequence evidence for the segmental allotetraploid origin of maize. Proceedings of the National Academy of Science (U.S.A.) 94 (1997) 6809–6814.
Hannenhalli, S., Pevzner, P.A.: Transforming cabbage into turnip. (polynomial algorithm for sorting signed permutations by reversals). In: Proceedings of the 27th Annual ACM-SIAM Symposium on the Theory of Computing (1995) 178–189.
Hannenhalli, S., Pevzner, P.A.: Transforming men into mice (polynomial algorithm for genomic distance problem). In: Proceedings of the IEEE 36th Annual Symposium on Foundations of Computer Science (1995) 581–592.
Rieseberg, L.H, Van Fossen, C., Desrochers, S.M.: Hybrid speciation accompanied by genomic reorganization in wild sunflowers. Nature 375 (1995) 313–316.
Sankoff, D., Blanchette, M.: The median problem for breakpoints in comparative genomics. In: Computing and Combinatorics, Proceeedings of COCOON’ 97. (T. Jiang and D.T. Lee, eds) Lecture Notes in Computer Science 1276 Springer Verlag (1997) 251–263.
Sankoff, D., Sundaram, G., Kececioglu, J.: Steiner points in the space of genome rearrangements. International Journal of the Foundations of Computer Science 7 (1996) 1–9.
Ungerer, M.C., Baird, S.J.E., Pan, J., Rieseberg, L.H.: Rapid hybrid speciation in wild sunflowers. Proceedings of the National Academy of Science (U.S.A.) 95 (1998) 11757–11762.
Watterson, G.A., Ewens, W.J., Hall, T.E., Morgan, A.: The chromosome inversion problem. Journal of Theoretical Biology 99 (1982) 1–7.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1999 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
El-Mabrouk, N., Sankoff, D. (1999). Hybridization and Genome Rearrangement. In: Crochemore, M., Paterson, M. (eds) Combinatorial Pattern Matching. CPM 1999. Lecture Notes in Computer Science, vol 1645. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-48452-3_6
Download citation
DOI: https://doi.org/10.1007/3-540-48452-3_6
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-66278-5
Online ISBN: 978-3-540-48452-3
eBook Packages: Springer Book Archive