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Mechanisms of abnormal gene expression in tumor cells

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Cancer: Cell Structures, Carcinogens and Genomic Instability

Part of the book series: Experientia Supplementum ((EXS,volume 96))

Abstract

Epigenetic mechanisms are involved in critical nuclear processes such as transcriptional control, genome stability, replication and repair. Recent evidence suggests that changes in the epigenetic repertoire can drive tumorigenesis. This review examines the latest experimental evidence that questions the mechanisms underlying the consequence of epigenetic changes in gene regulation and cancer development.

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  1. Baker Medical Research Institute, Epigenetics in Human Health and Disease Laboratory, The Alfred Medical Research and Education Precinct (AMREP), Second Floor, Commercial Road, Prahran, Victoria, 3181, Australia

    Assam El-Osta

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© 2006 Birkhäuser Verlag/Switzerland

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El-Osta, A. (2006). Mechanisms of abnormal gene expression in tumor cells. In: Cancer: Cell Structures, Carcinogens and Genomic Instability. Experientia Supplementum, vol 96. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7378-4_15

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