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Literaturverzeichnis

  1. AIMS Trial Study Group (1988) Effect of intravenous APSAC on mortality after acute myocardial infarction: preliminary report of a placebo-controlled clinical trial. Lancet Mar 12; 1(8585):545–549

    Google Scholar 

  2. Ambrosioni E, Borghi C, Magnani B, for the Survival of Myocardial Infarction Long-Term Evaluation (SMILE) Study Investigators (1995) The effect of the angiotensin-converting enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction. N Engl J Med 332:80–85

    Article  PubMed  Google Scholar 

  3. Antman EM, McCabe CH, Gurfinkel EP et al (1999) Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q-wave myocardial infarction. Results of the thrombolysis in myocardial infarction TIMI 11B trial. Circulation 100:1593–1601

    PubMed  Google Scholar 

  4. Aronow WS (1989) New coronary events of four-year follow-up in elderly patients with recognized or unrecognized myocardial infarction. Am J Cardiol 63:621–622

    Article  PubMed  Google Scholar 

  5. Aronow WS (2001) Treatment of the elderly post-myocardial infarction patient. Am J Geriatr Cardiol 10:316–322, 376

    PubMed  Google Scholar 

  6. Aronow WS, Epstein S (1990) Usefulness of silent ischemia, ventricular tachycardia, and complex ventricular arrhythmias in predicting new coronary events in elderly patients with coronary artery disease or systemic hypertension. Am J Cardiol 65:511–512

    Article  PubMed  Google Scholar 

  7. Aronow WS, Epstein S (2001) Usefulness of silent myocardial ischemia detected by ambulatory electrocardiographic monitoring in predicting new coronary events in elderly patients. Am J Cardiol 62:1295–1296

    Article  Google Scholar 

  8. Asia K, Kudej RK, Shen YT et al (2000) Peripheral vascular endothelial dysfunction and apoptosis in old monkeys. Arterioscl Thromb Vasc Biol 20:1493–1499

    PubMed  Google Scholar 

  9. Ayanian JZ, Braunwald E (2000) Thrombolytic therapy for patients with myocardial infarction who are older than 75 years. Circulation 101:2224–2226

    PubMed  Google Scholar 

  10. Azhar G, Gao W, Liu L et al (1999) Ischemia-reperfusion in the adult mouse heart influence of age. Exp Gerontol 34:699–714

    Article  PubMed  Google Scholar 

  11. Bayer AJ, Chadha JS, Farag RR et al (1986) Changing presentation of myocardial infarction with increasing old age. J Am Geriatr Soc 34:263–266

    PubMed  Google Scholar 

  12. Bennet CL, Weinberg PD, Rozenberg-Ben-Dror K et al (1998) Thrombotic thrombocytopenic purpura associated with ticlopidine: a review of 60 cases. Ann Intern Med 128:541–544

    PubMed  Google Scholar 

  13. Berger AK, Schulman KA, Gersh BJ et al (1999) Primary coronary angioplasty vs. thrombolysis for the management of acute myocardial infarction in elderly patients. JAMA 282:341–348

    Article  PubMed  Google Scholar 

  14. Bertrand ME, Rupprecht HJ, Urban P et al (2000) Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting: the Clopidogrel Aspirin Stent International Cooperative Study (CLASSICS). Circulation 102:624–629

    PubMed  Google Scholar 

  15. Boden WE, O’Rourke RA, Crawford MH et al (1998) Veterans Affairs Non-Q-Wave Infarction Strategies in Hospital (VANQWISH) Trial Investigators. Outcomes in patients with acute non-Q-wave myocardial infarction randomly assigned to an invasive as compared with a conservative management strategy. N Engl J Med 338:1785–1792

    Article  PubMed  Google Scholar 

  16. Brass LM, Lichtman JH, Wang Y et al (2000) Intracranial hemorrhage associated with thrombolytic therapy for elderly patients with acute myocardial infarction: results from the Cooperative Cardiovascular Projekt. Stroke 31:1802–1811

    PubMed  Google Scholar 

  17. Braunwald E, Antman EM, Beasley JW et al (2000) ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 36:971–1062

    Article  Google Scholar 

  18. Brener SJ, Barr LA, Burchenal JE et al (1998) Randomized, placebo-controlled trial of platelet glycoprotein IIb/IIIa blockade with primary angioplasty for acute myocardial infarction. ReoPro and Primary, PTCA Organization and Randomized Trial (RAPPORT) Investigators. Circulation 98:734–741

    PubMed  Google Scholar 

  19. Bueno H, Lopez-Palop R, Bermejo J et al (1996) High short-term mortality of elderly patients with first acute inferior myocardial infarctions. J Am Coll Cardiol 27:340A

    Article  Google Scholar 

  20. Cannon C (2001) TACTICS-TIMI 18 (Treat angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy). N Engl J Med 344:1879–1887

    Article  PubMed  Google Scholar 

  21. Cannon CP (2003) Elderly patients with acute coronary syndromes: higher risk and greater benefit from antiplatelet therapy and/or interventional therapies. Am J Geriatr Cardiol 12:259–262

    PubMed  Google Scholar 

  22. CAPRIE Steering Committee (1996) A randomised, blinded trial of Clopidogrel versus Aspirin in patients at risk of ischaemic events (CAPRIE). Lancet 348:1329–1339

    Google Scholar 

  23. Chauhan MS, Kuntz RE, Ho KK et al (2001) Coronary artery stenting in the aged. J Am Coll Cardiol 37:856–862

    Article  PubMed  Google Scholar 

  24. Clark LT, Gerfein OB, Dwyer EM (1983) Acute pulmonary edema due to ischemic heart disease without accompanying myocardial infarction. Am J Med 75:332–336

    Article  PubMed  Google Scholar 

  25. Cohen M, Demers C, Gurfinel EP et al (1997) A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q Wave Coronary Events Study Group. N Engl J Med 337:447–452

    Article  PubMed  Google Scholar 

  26. Cohen M, Demers C, Gurfinkel E et al, for the Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group (1997) A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. N Engl J Med 337:447–452

    Article  PubMed  Google Scholar 

  27. CURE Trial Investigators (2001) Clopidogrel in unstable angina to prevent recurrent events. N Engl J Med 345:494–502

    Google Scholar 

  28. De Lemos, Antmann EM, Gibson CM et al for the Thrombolysis in Myocardial Infarction (TIMI) 14 investigators (2000) Abciximab improves both epicardial flo and myocardial perfusion in ST elevation myocardial infarction: observations from the TIMI 14 trial. Circulation 101:239–243

    PubMed  Google Scholar 

  29. Ernst E, Resch KL (1993) Fibrinogen as a cardiovascular risk factor: a meta-analysis and review of the literature. Ann Intern Med 118:956–963

    PubMed  Google Scholar 

  30. Every NR, Parsons LS, Hlatky M et al (1996) A comparison of thrombolytic therapy with primary coronary angioplasty for acute myocardial infarction. N Engl J Med 335:1253–1260

    Article  PubMed  Google Scholar 

  31. Fath-Ordoubadi F, Beatt KJ (1997) Glucose-insulin-potassium Therapy for treatment of acute myocardial infarction: an overview of randomized placebo-controlled trials. Circulation 96:1152–1156

    PubMed  Google Scholar 

  32. Ferguson JJ, Diver DJ, Boldt M et al (1989) Significance of nitroglycerin-induced hypotension with inferior wall acute myocardial infarction. Am J Cardiol 64:311–314

    Article  PubMed  Google Scholar 

  33. Fibrinolytic Therapy Trialists (FTT) Collaborative Group (1994) Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Lancet 343:311–322

    Google Scholar 

  34. Frasure-Smith N, Lesperance F, Talajic M (1993) Depression following myocardial infarction. JAMA 270:1819–1825

    Article  PubMed  Google Scholar 

  35. Gillum RF (1993) Trends in acute myocardial infarction and coronary heart disease death in the United States. J Am Coll Cardiol 23:1273–1277

    Google Scholar 

  36. Graham SP, Vetrovec GW (1991) Comparison of angiographic findings and demographic variables in patients with coronary artery disease presenting with acute pulmonary edema versus those presenting with chest pain. Am J Cardiol 68:1614–1618

    Article  PubMed  Google Scholar 

  37. Graves EJ (1992) National hospital discharge survey: annual summary 1990. National Center for Health Statistics, Public Health Service. Vital Health Stat 13(112):1–62

    Google Scholar 

  38. Gregoratos G (2001) Clinical manifestations of acute myocardial infarction in older patients. Am J Geriatr Cardiol 10:345–347

    PubMed  Google Scholar 

  39. Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (1994) GISSI-3: effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. Lancet 343:1115–1122

    Google Scholar 

  40. Gruppo Italiano per lo Studio della Streptochinasi nell’Infarto Miocardico (GISSI) (1986) Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet 1(8478):397–402

    Google Scholar 

  41. Gunderson T, Abrahamsen AM, Kjekshus J et al (1982) Timolol-related reduction in mortality and reinfarction in patients ages 65–75 years surviving acute myocardial infarction. Circulation 66:1179–1184

    PubMed  Google Scholar 

  42. Headrick JP (1998) Aging impairs functional, metabolic, and ionic recovery from ischema-reperfusion and hypoxia-reoxygenation. J Mol Cell Cardiol 30:1415–1430

    Article  PubMed  Google Scholar 

  43. Hedblad B, Juul-Moller S, Svensson K et al (1989) Increased mortality in men with ST segment depression during 24 h ambulatory long-term ECG recording: results from prospective population study “Men born in 1914 from Malmo, Sweden. Eur Heart J 10:149–158

    PubMed  Google Scholar 

  44. Hjalmarson A, Elmfeldt D, Herlitz J et al (1981) Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial. Lancet 2(8251):823–827

    Article  PubMed  Google Scholar 

  45. Hochman JS, Sleeper LA, Webb JG et al (1999) Early revascularization in acute myocardial infarction complicated by cardiogenic shock. N Engl J Med 341:625–634

    Article  PubMed  Google Scholar 

  46. Holmes DR, White HD, Pieper KS et al (1999) Effect of age on outcome with primary angioplasty versus thrombolysis. J Am Coll Cardiol 33:412–419

    Article  PubMed  Google Scholar 

  47. Hung J, Whitford EG, Parsons RW et al (1990) Association of sleep apnea with myocardial infarction in men. Lancet 336:261–264

    Article  PubMed  Google Scholar 

  48. ISIS-1 (First International Study of Infarct Survival) Collaborative Group (1986) Randomised trial of intravenous atenolol among 16,027 cases of suspected acute myocardial infarction: ISIS-1. Lancet 2(8498):57–66

    Google Scholar 

  49. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group (1988) Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 2:349–360

    Google Scholar 

  50. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group (1995) ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. Lancet 345:669–685

    Google Scholar 

  51. Jonsdottir LS, Sigfusson N, Sigvaldason H et al (1998) Incidence and prevalence of recognised and unrecognised myocardial infaction in women: the Reykjavik Study. Eur Heart J 19:1011–1018

    Article  PubMed  Google Scholar 

  52. Kannel WB (1998) Prospects for prevention of cardiovascular disease in the elderly. Prev Cardiol 1:32–39

    Google Scholar 

  53. Kannel WB (2002) Coronary heart disease risk factors in the elderly. Am J Gariatr Cardiol 11:101–107

    Google Scholar 

  54. Kannel WB, Abbot RD (1984) Incidence and prognosis of unrecognized myocardial infarction: an update on the Framingham Study. N Engl J Med 311:1144–1147

    PubMed  Google Scholar 

  55. Kannel WB, Belanger AJ (1991) Epidemiology of heart failure. Am Heart J 121:951–957

    Article  PubMed  Google Scholar 

  56. Kannel WB, D’Agostino RB (1995) The importance of cardiovascular risk factors in the elderly. Am J Geriatr Cardiol 4(2):10–23

    Google Scholar 

  57. Kannel WB, Dannenberg Al, Abbott RD (1985) Unrecognized myocardial infarction in hypertension. The Framingham Study. Am Heart J 109:581–585

    Article  PubMed  Google Scholar 

  58. Kannel WB, Hjortland MC, McNamara PM et al (1976) Menopause and the risk of cardiovascular disease. The Framingham Study. Ann Intern Med 85:447–452

    PubMed  Google Scholar 

  59. Kannel WB, Vokonas PS (1992) Demographics of the prevalence, incidence, and management of coronary disease in the elderly and women. Ann Epidemiol 2:5–14

    PubMed  Google Scholar 

  60. Klein LW, Block P, Brindis RG et al (2002) Percutaneous coronary interventions in octogenarians in the American College of Cardiology — National Cardiovascular Data Registry: development of a nomogram predictive of inhospital mortality. J Am Coll Cardiol 40:394–402

    Article  PubMed  Google Scholar 

  61. Krumholz HM, Hennen J, Ridker PM et al (1998) Use and effectiveness of intravenous heparin therapy for treatment of acute myocardial infarction in the elderly. J Am Coll Cardiol 31:973–979

    Article  PubMed  Google Scholar 

  62. Krumholz HM, Murillo JE, Chen, J et al (1997) Thrombolytic therapy for eligible elderly patients with acute myocardial infarction. JAMA 277:1683–1688

    Article  PubMed  Google Scholar 

  63. Kunis R, Greenberg H, Yeoh CP et al (1985) Coronary revascularization of recurrent pulmonary edema in elderly patients with ischemic heart disease and preserved ventricular function. N Engl J Med 313:1207–1210

    PubMed  Google Scholar 

  64. Lane GE, Holmes DR (2000) Primary angioplasty for acute myocardial infarction in the elderly. Coron Artery Dis 11:305–313

    Article  PubMed  Google Scholar 

  65. LaRosa JC (1995) Should high lipid levels in very old patients be lowered? Drugs Aging 6:85–90

    PubMed  Google Scholar 

  66. Lavie CJ, Milani RV (1995) Effects of cardiac rehabilitation programs on exercise capacity, coronary risk factors, behavioral characteristics, and quality of life in a large elderly cohort. Am J Cardiol 76:177–179

    Article  PubMed  Google Scholar 

  67. Lavie CJ, Milani RV (1996) Effects of cardiac rehabilitation and exercise training in obese patients with coronary artery disease. Chest 109:52–56

    PubMed  Google Scholar 

  68. Lavie CJ, Milani RV (1996) Effects of cardiac rehabilitation programs in very elderly patients 275 years of age. Am J Cardiol 78:675–677

    Article  PubMed  Google Scholar 

  69. Lavie CJ, Milani RV (1997) Benefits of cardiac rehabilitation and exercise training in elderly women. Am J Cardiol 79:664–666

    Article  PubMed  Google Scholar 

  70. Lavie CJ, Milani RV (1997) Effects of cardiac rehabilitation, exercise training, and weight reduction on exercise capacity, coronary risk factors, behavioral characteristics, and quality of life in obese coronary patients. Am J Cardiol 79:397–401

    Article  PubMed  Google Scholar 

  71. Lavie CJ, Milani RV (2001) Benefits of cardiac rehabilitation and exercise training programs in elderly coronary patients. Am J Geriatr Cardiol 10:323–327

    PubMed  Google Scholar 

  72. Lavie CJ, Milani RV, Littmann AB (1993) Benefits of cardiac rehabilitation and exercise training in secondary coronary prevention in the elderly. J Am Coll Cardiol 22:678–683

    PubMed  Google Scholar 

  73. Little T, Lindsay J (1994) Percutaneous transluminal coronary angioplasty and coronary artery bypass graft surgery in octogenarians: indications and outcome. Heart Disease and Stroke 3:261–265

    PubMed  Google Scholar 

  74. Maggioni AP, Maseri A, Fresco C et al (1993) Age-related increase in mortality among patients with first myocardial infarctions treated with thrombolysis. The investigators of the Gruppo Italiano per lo Studio della Sopravivenza nell’Infarcto Miocardico (GISSI-2). N Engl J Med 329:1442–1448

    Article  PubMed  Google Scholar 

  75. Magid DJ, Calonge BN, Rumsfeld JS et al (2000) Relation between hospital primary angioplasty volume and mortality for patients with acute MI treated with primary angioplasty vs. thrombolytic therapy. JAMA 284:3131–3138

    Article  PubMed  Google Scholar 

  76. Mak KH, Effron MB, Moliterno DJ (2000) Platelet glycoprotein IIb/IIIa receptor antagonists and their use in elderly patients. Drugs Aging 16: 179–187

    PubMed  Google Scholar 

  77. Milani RV, Littman AB, Lavie CJ (1993) Psychological adaptation to cardiovascular disease. In: Messerli FH (ed) Cardiovascular disease in the elderly, 3rd edn. Kluver Academic Publishers, Norwell, MA; pp 401–412

    Google Scholar 

  78. Montalescot G, Barragan P, Wittenberg O et al (2001) Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction. N Engl J Med 344:1895–1903

    Article  PubMed  Google Scholar 

  79. National Heart, Lung, and Blood Institute (2000) Morbidity and mortality 2000: chartbook on cardiovascular, lung, and blood diseases. US Department of Health and Human Services, Bethesda, MD

    Google Scholar 

  80. Neumann FJ, Kastrati A, Schmitt C et al (2000) Effect of glycoprotein IIb/IIIa receptor blockade with abciximab on clinical and angiographic restenosis rate after the placement of coronary stents following acute myocardial infarction. J Am Coll Cardiol 35:915–921

    Article  PubMed  Google Scholar 

  81. O’Rourke RA, Hochman JS, Cohen MC et al (2001) New approaches to diagnosis and management of unstable angina and non-ST-segment elevation myocardial infarction. Arch Intern Med 161:674–682

    Article  PubMed  Google Scholar 

  82. Pathy MS (1967) Clinical presentation of myocardial infarction in the elderly. Br Heart J 29:190–199

    PubMed  Google Scholar 

  83. Pfeffer MA, Domanski M, Rosenbert Y et al (1998) Prevention of events with angiotensin-converting enzyme inhibition. Am J Cardiol 82:25H–30H

    Article  PubMed  Google Scholar 

  84. Popovic JR, Kozak LJ (1998) National Hospital Discharge Survey: annual summary. Vital Health Stat 13(148):1–194

    Google Scholar 

  85. Reeder GS (2000) Contemporary diagnosis and management of unstable angina. Mayo Clin Proc 75:953–957

    PubMed  Google Scholar 

  86. Rich MW (2001) Treatment of acute myocardial infarction. Am J Geriatr Cardiol 10:328–336

    PubMed  Google Scholar 

  87. Roberts R, Robers WJ, Mueller HS et al (1991) Immediate vs. deferred β-blockade following thrombolytic therapy in patients with acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction TIMI II-B Study. Circulation 83:422–437

    PubMed  Google Scholar 

  88. Rodstein M (1956) The characteristics of non-fatal myocardial infarction in the aged. Arch Intern Med 98:84–90

    Google Scholar 

  89. Rogers WJ, Canto JG, Lambrew CT et al (2000) Temporal trends in the treatment of over 1.5 million patients with myocardial infarction in the US from 1990 through 1999. The National Registry of Myocardial Infarction 1, 2 and 3. J am Coll Cardiol 36:2056–2063

    Article  PubMed  Google Scholar 

  90. Ross AM (1990) The TTOPP Study: lessons from an aborted trial. J Myocardial Ischema 2:65–69

    Google Scholar 

  91. Rutsch W (2001) Koronarinterventionen im Alter. Herzmedizin 18:186–193

    Google Scholar 

  92. Ryan TJ, Anderson JL, Antman EM et al (1996) ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol 28:673–682

    Article  PubMed  Google Scholar 

  93. Schuler J, Matteucci-Gothe R (2003) Therapie des akuten Myokardinfarktes im Alter > 75 Jahre — Daten aus dem Berliner Herzinfarktregister (BHIR). Z Kardiologie 92(suppl 1):I/99

    Google Scholar 

  94. Schwartz G (2001) Myocardial ischemic reduction with aggressive cholesterol-lowering (MIRACLE). JAMA 285:1711–1818

    Article  PubMed  Google Scholar 

  95. Sheifer SE, Gersh BJ Phil D et al (2000) Prevalence, predisposing factors, and prognosis of clinically unrecognized myocardial infarction in the elderly. J Am Coll Cardiol 5:119–126

    Article  Google Scholar 

  96. Siegel R, Clements T, Wingo M et al (1991) Acute heart failure in elderly: another manifestation of unstable „angina“. J Am Coll Cardiol 17:149A

    Google Scholar 

  97. Smith SC, Gilpin E, Ahnve S et al (1990) Outlook for acute myocardial infarction in the very elderly compared with that in patients 65–75 years. J Am Coll Cardiol 16:784–792

    PubMed  Google Scholar 

  98. Stone GW, Grines CL, Cox DA et al (2002) Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction. N Engl J Med 346:957–966

    Article  PubMed  Google Scholar 

  99. Stone PH, Thompson B, Anderson V et al (1996) Influence of race, sex, and age on management of unstable angina and non-Q-wave myocardial infarction. The TIMI III Registry. JAMA 275:1104–1112

    Article  PubMed  Google Scholar 

  100. The Antiplatelet Trialist’s Collaboration (1994) Collaborative overview of randomized trials of antiplatelet therapy. I: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Br Med J 308:81–106

    Google Scholar 

  101. The Assessment of the Safety and Efficacy of the New Thrombolytic Regimen (ASSENT)-3 Investigators (2001) Efficacy and safety of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: the ASSENT-3 randomised trial in acute myocardial infarction. Lancet 358:605–613

    Google Scholar 

  102. The Clopidogrel in Unstable Angina to Prevent Recurrent Ischemic Events Trial Investigators (2001) Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment evaluation. N Engl J Med 345:494–502

    Google Scholar 

  103. The EPIC Investigators (1994) Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. N Engl J Med 330:956–961

    Google Scholar 

  104. The EPILOG Investigators (1997) Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med 336:1689–1696

    Google Scholar 

  105. The F.R.A.X.I.S. Study Group (1999) Comparison of two treatment durations (6 days and 14 days) of a low-molecular-weight heparin with a 6-day treatment of unfractionated heparin in the initial management of unstable angina or non-Q-wave myocardial infarction: FRAXIS (FRAXiparine in Ischaemic Syndrome). Eur Heart J 20(21):1553–1562

    Google Scholar 

  106. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO III) Investigators (1997) A comparison of reteplase with alteplase for acute myocardial infarction. N Engl J Med 337:1118–1123

    Google Scholar 

  107. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators (1996) A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med 335:775–782

    Google Scholar 

  108. The Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO IIb) Angioplasty Substudy Investigators (1997) A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction. N Engl J Med 336:1621–1628

    Google Scholar 

  109. The GUSTO Investigators (1993) An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N Engl J Med 329:673–682

    Google Scholar 

  110. The ISAM Study Group (1986) A prospective trial of intravenous streptokinase in acute myocardial infarction (ISAM). Mortality, morbidity, and infarct size at 21 days. N Engl J Med 314:1465–1471

    Google Scholar 

  111. The MIAMI Trial Research Group (1985) Metoprolol in acute myocardial infarction (MIAMI). A randomised placebo-controlled international trial. Eur Heart J 6:199–226

    Google Scholar 

  112. The Norwegian Multicenter Study Group (1981) Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction. N Engl J Med 304:801–807

    Google Scholar 

  113. The Platelet Receptor Inhibition in Ischemic Syndrom Management (PRISM) Study Investigators (1998) A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina. N Engl J Med 338:1498–1505

    Google Scholar 

  114. The Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Investigators (1998) Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q wave myocardial infarction. N Engl J Med 338:1488–1497

    Google Scholar 

  115. The PURSUIT Trial Investigators (1998) Inhibition of platelet glycoprotein IIb/IIIa with epitfibatide in patients with acute coronary syndromes: platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using Integrilin therapy. N Engl J Med 339:436–443

    Google Scholar 

  116. The Task Force on the management of acute myocardial infarction of the European Society of Cardiology (2003) Task Force Report: management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 24:28–66

    Google Scholar 

  117. The TIMI IIIB Investigators (1994) Effects of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction: results of the TIMI IIIB Trial. Circulation 89:1545–1556

    Google Scholar 

  118. Topol EJ, The GUSTO V Investigators (2001) Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: the GUSTO V randomised Trial. Lancet 357:1905–1914

    Article  PubMed  Google Scholar 

  119. Tresch DD, Alla HR (2001) Diagnosis and management of myocardial ischemia (angina) in the elderly patient. Am J Geratir Cardiol 10:337–344

    Google Scholar 

  120. Tresch DD, Saeian K, Hoffman R (1992) Elderly patients with late onset of coronary artery disease: clinical and angiographic findings. Am J Geriatr Cardiol 1:14–25

    PubMed  Google Scholar 

  121. Tryan TJ, Antman EM, Brooks NH et al (1999) 1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction: executive summary and recommendations. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). Circulation 100:1016–1030

    PubMed  Google Scholar 

  122. Urban P, Macaya C, Rupprecht HJ et al (1998) Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients: the multicenter aspirin and ticlopidine trial after intracoronary stenting (MATTIS). Circulation 98:2126–2132

    PubMed  Google Scholar 

  123. Vokonas PS, Kannel WB, Cupples LA (1988) Incidence and prognosis of unrecognized myocardial infarction in the elderly: the Framingham Study. J Am Coll Cardiol 11:51A

    Google Scholar 

  124. Wallentin L, for the FRISC II (Fragmin and Fast Revascularization During InStability in Coronary Artery Disease) Investigators (1999) Invasive compared with non-invasive treatment in unstable coronary artery disease: FRISC II prospective randomized multicenter study. Lancet 354:708–715

    Article  PubMed  Google Scholar 

  125. Wilcox RG, von der Lippe G, Olsson CG et al (1988) Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction. Anglo-Scandinavian Study of Early Thrombolysis (ASSET). Lancet 2(8610):525–530

    Article  PubMed  Google Scholar 

  126. Wilson PWF, Kannel WB (1993) Hypercholesterolemia and coronary risk in the elderly: the Framingham Study. Am J Geriatr Cardiol 2:56

    PubMed  Google Scholar 

  127. Yusuf S, Dzau VJ, Lonn E et al (2000) New findings and implications of the HOPE Study. Clin Geriatr (Suppl):1–8

    Google Scholar 

  128. Yusuf S, Flather M, Pogue J et al OASIS (Organisation to Access Strategies for Ischaemic Syndromes) Registry Investigators (1998) Variations between countries in invasive cardiac procedures and outcomes in patients with suspected unstable angina or myocardial infarction without initial ST elevation. Lancet 352:507–514

    Article  PubMed  Google Scholar 

  129. Yusuf S, Slight P, Pogue J et al (2000) Effects of an angiotensin-converting enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 342:145–153

    Article  PubMed  Google Scholar 

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© 2005 Steinkopff Verlag Darmstadt

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(2005). Koronare Herzkrankheit. In: Geriatrische Kardiologie. Steinkopff. https://doi.org/10.1007/3-7985-1530-1_5

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  • DOI: https://doi.org/10.1007/3-7985-1530-1_5

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-1459-1

  • Online ISBN: 978-3-7985-1530-7

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