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Trichomonas vaginalis Pharmacological Treatment

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Antiprotozoal Drug Development and Delivery

Part of the book series: Topics in Medicinal Chemistry ((TMC,volume 39))

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Abstract

Trichomoniasis is the most common sexually transmitted protozoan infection, which has been treated for several decades using nitroimidazoles, mainly metronidazole and tinidazole. Both drugs are still recommended and resistance to them has fortunately been a relatively rare phenomenon. Resistant or tolerant cases exist, however, side effects are also notable. Therefore, novel compounds with different mechanism of action are urgently needed. It is encouraging that several novel and innovative leads have been introduced. They will hopefully help us to develop novel antitrichomonal agents to fight harder against this parasitic disease in the future.

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Authors and Affiliations

  1. Faculty of Medicine and Health Technology, Tampere University and Fimlab Laboratories Ltd., Tampere University Hospital, Tampere, Finland

    Seppo Parkkila

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  1. Seppo Parkkila
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Correspondence to Seppo Parkkila .

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Editors and Affiliations

  1. Biotechnology Center-Bioinovar, Biocatalysis, Bioproducts and Bioenergy Unit, Institute of Microbiology Paulo de Góes, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Alane Beatriz Vermelho

  2. Polo Scientifico, Laboratorio di Ch, University of Florence, Neurofarba Department, Sesto Fiorentino, Italy

    Claudiu T. Supuran

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Conflict of Interest: The author declares that he has no conflict of interest.

Funding: Original research of our team is funded by the Academy of Finland and Jane & Aatos Erkko Foundation.

Ethical Approval: This chapter does not contain any studies with human participants or animals performed by the author.

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Parkkila, S. (2021). Trichomonas vaginalis Pharmacological Treatment. In: Vermelho, A.B., Supuran, C.T. (eds) Antiprotozoal Drug Development and Delivery. Topics in Medicinal Chemistry, vol 39. Springer, Cham. https://doi.org/10.1007/7355_2021_123

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