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Extraintestinal Pathogenic Escherichia coli

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Escherichia coli, a Versatile Pathogen

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 416))

Abstract

Extraintestinal pathogenic E. coli (ExPEC) present a major clinical problem that has emerged in the past years. Most of the infections are hospital or community-acquired and involve patients with a compromised immune system. The infective agents belong to a large number of strains of different serotypes that do not cross react. The seriousness of the infection is due to the fact that most of the infecting bacteria are highly antibiotic resistant. Here, we discuss the bacterial factors responsible for pathogenesis and potential means to combat the infections.

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Acknowledgements

This project was supported by a DIP grant from the German-Israeli Project Cooperation (RO 2612/1-1), by the EC Network of Excellence Euro-PathoGenomics (CEE LSHB-CT-2005-512061), by the ERA-NET Pathogenomics project COLIRISK, by the JPIAMR (Joint Programming Initiative on Antimicrobial Resistance), by the Infect Era EC ERA-NET and by the Israeli Ministry of Health.

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  1. Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel Aviv University, 39978, Tel Aviv, Israel

    Dvora Biran & Eliora Z. Ron

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  1. Dvora Biran
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  2. Eliora Z. Ron
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Correspondence to Eliora Z. Ron .

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  1. Department of Life Sciences, Imperial College London, London, UK

    Gad Frankel

  2. Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel

    Eliora Z Ron

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Biran, D., Ron, E.Z. (2018). Extraintestinal Pathogenic Escherichia coli. In: Frankel, G., Ron, E. (eds) Escherichia coli, a Versatile Pathogen. Current Topics in Microbiology and Immunology, vol 416. Springer, Cham. https://doi.org/10.1007/82_2018_108

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