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Second Malignancies After Radiation Treatment and Chemotherapy for Primary Cancers

  • Chapter
Cancer Survivorship

Abstract

Cancer survivors have been shown to have an increased risk for second malignant neoplasms (SMN). These increased risks result from genetic predisposition, harmful environmental exposures, or cancer treatment therapies. Regardless of their cause, SMNs now comprise the sixth most common group of malignancies after skin, prostate, breast, lung, and colorectal cancers.1 It is important to emphasize that the fear of SMN related to the treatment of the first cancer diagnosis should not outweigh the positive effects of curative therapy for the first cancer. Both physicians and patients should, however, be aware of the consequences of the cancer treatment regimens, specifically radiation therapy (RT) and chemotherapy, and consider them while devising follow-up plans.

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Author information

Authors and Affiliations

  1. Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA

    Lydia B. Zablotska M.D., Ph.D. (Assistant Professor)

  2. Department of Medicine, Columbia University Medical Center, New York, New York, USA

    Matthew J. Matasar M.D. (Instructor)

  3. Department of Epidemiology, Mailman School of Public Health, USA

    Alfred I. Neugut M.D., Ph.D. (Professor)

  4. Department of Medicine, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York, USA

    Alfred I. Neugut M.D., Ph.D. (Professor)

Authors
  1. Lydia B. Zablotska M.D., Ph.D.
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  2. Matthew J. Matasar M.D.
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  3. Alfred I. Neugut M.D., Ph.D.
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Editors and Affiliations

  1. Division of Cancer Prevention and Control Research Jonsson Comprehensive Cancer Center, UCLA Schools of Public Health and Medicine, Los Angeles, CA, 90095-6900, USA

    Patricia A. Ganz M.D. (American Cancer Society Research Professor) (American Cancer Society Research Professor)

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© 2007 Springer Science+Business Media, LLC

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Zablotska, L.B., Matasar, M.J., Neugut, A.I. (2007). Second Malignancies After Radiation Treatment and Chemotherapy for Primary Cancers. In: Ganz, P.A. (eds) Cancer Survivorship. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68265-5_17

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  • DOI: https://doi.org/10.1007/978-0-387-68265-5_17

  • Publisher Name: Springer, New York, NY

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  • Online ISBN: 978-0-387-68265-5

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