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Cavernous Malformations and Other Vascular Abnormalities: Observation-Alone Perspective

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Principles and Practice of Stereotactic Radiosurgery

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Abstract

Observation alone as a reasonable option in management of cavernous malformations (CMs) or other vascular abnormalities can only be justified based on a favorable comparison between the natural history of the lesion and the expected effi- cacy and risks of treatment. For each lesion type in question, we will review existing knowledge regarding natural history in comparison with the effects of radiosurgical treatment.

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References

  1. Robinson JR, Awad IA, Little JR. Natural history of the cavernous angioma. J Neurosurg 1991; 75(5):709–714.

    Article  CAS  PubMed  Google Scholar 

  2. Del Curling O Jr, Kelly DL Jr, Elster AD, Craven TE. An analysis of the natural history of cavernous angiomas. J Neurosurg 1991; 75(5):702–708.

    Article  PubMed  Google Scholar 

  3. Aiba T, Tanaka R, Koike T, et al. Natural history of intracranial cavernous malformations. J Neurosurg 1995; 83(1):56–59.

    Article  CAS  PubMed  Google Scholar 

  4. Zabramski JM, Wascher TM, Spetzler RF, et al. The natural history of familial cavernous malformations: results of an ongoing study. J Neurosurg 1994; 80(3):422–432.

    Article  CAS  PubMed  Google Scholar 

  5. Porter PJ, Willinsky RA, Harper W, Wallace MC. Cerebral cavernous malformations: natural history and prognosis after clinical deterioration with or without hemorrhage. J Neurosurg 1997; 87(2):190–197.

    Article  CAS  PubMed  Google Scholar 

  6. Kondziolka D, Lunsford LD, Kestle JR. The natural history of cerebral cavernous malformations. J Neurosurg 1995; 83(5):820–824.

    Article  CAS  PubMed  Google Scholar 

  7. Robinson JR Jr, Awad IA, Magdinec M, Paranandi L. Factors predisposing to clinical disability in patients with cavernous malformations of the brain. Neurosurgery 1993; 32(5):730–735; discussion 735–736.

    Article  PubMed  Google Scholar 

  8. Labauge P, Brunereau L, Levy C, et al. The natural history of familial cerebral cavernomas: a retrospective MRI study of 40 patients. Neuroradiology 2000; 42(5):327–332.

    Article  CAS  PubMed  Google Scholar 

  9. Moriarity JL, Clatterbuck RE, Rigamonti D. The natural history of cavernous malformations. Neurosurg Clin N Am 1999; 10(3):411–417.

    CAS  PubMed  Google Scholar 

  10. Kim DS, Park YG, Choi JU, et al. An analysis of the natural history of cavernous malformations. Surg Neurol 1997; 48(1):9–17; discussion 18.

    Article  CAS  PubMed  Google Scholar 

  11. Kupersmith MJ, Kalish H, Epstein F, et al. Natural history of brainstem cavernous malformations. [see comment]. Neurosurgery 2001; 48(1):47–53; discussion 54.

    Article  CAS  PubMed  Google Scholar 

  12. Barker FG 2nd, Amin-Hanjani S, Butler WE, et al. Temporal clustering of hemorrhages from untreated cavernous malformations of the central nervous system. Neurosurgery 2001; 49(1):15–24; discussion 25.

    Article  PubMed  Google Scholar 

  13. Pozzati E, Acciarri N, Tognetti F, et al. Growth, subsequent bleeding, and de novo appearance of cerebral cavernous angiomas. Neurosurgery 1996; 38(4):662–669; discussion 669–670.

    Article  CAS  PubMed  Google Scholar 

  14. Tung H, Giannotta SL, Chandrasoma PT, Zee CS. Recurrent intraparenchymal hemorrhages from angiographically occult vascular malformations. [see comment]. J Neurosurg 1990; 73(2):174–180.

    Article  CAS  PubMed  Google Scholar 

  15. Awad I. Steretoactic radisourgery for cavernous malformations (comment). Neurosurgery 1998; 42:1237.

    Article  Google Scholar 

  16. Amin-Hanjani S, Ogilvy CS, Candia GJ, et al. Stereotactic radiosurgery for cavernous malformations: Kjellberg’s experience with proton beam therapy in 98 cases at the Harvard Cyclotron. [see comment]. Neurosurgery 1998; 42(6):1229–1236; discussion 1236–1238.

    Article  CAS  PubMed  Google Scholar 

  17. Hasegawa T, McInerney J, Kondziolka D, et al. Long-term results after stereotactic radiosurgery for patients with cavernous malformations. Neurosurgery 2002; 50(6):1190–1197; discussion 1197–1198.

    Article  PubMed  Google Scholar 

  18. Kondziolka D, Lunsford LD, Flickinger JC, Kestle JR. Reduction of hemorrhage risk after stereotactic radiosurgery for cavernous malformations. [see comment]. J Neurosurg 1995; 83(5):825–831.

    Article  CAS  PubMed  Google Scholar 

  19. Chang SD, Levy RP, Adler JR Jr, et al. Stereotactic radiosurgery of angiographically occult vascular malformations: 14-year experience. Neurosurgery 1998; 43(2):213–220; discussion 220–221.

    Article  CAS  PubMed  Google Scholar 

  20. Karlsson B, Kihlstrom L, Lindquist C, et al. Radiosurgery for cavernous malformations. J Neurosurg 1998; 88(2):293–297.

    Article  CAS  PubMed  Google Scholar 

  21. Kim DG, Choe WJ, Paek SH, et al. Radiosurgery of intracranial cavernous malformations. Acta Neurochir 2002; 144(9):869–878; discussion 878.

    Article  CAS  Google Scholar 

  22. Pollock BE, Garces YI, Stafford SL, et al. Stereotactic radiosurgery for cavernous malformations. J Neurosurg 2000; 93(6):987–991.

    Article  CAS  PubMed  Google Scholar 

  23. Barker F 2nd, Amin-Hanjani S, Butler W, et al. Complication rates after radisourgery for cavernous malformations. Neurosurgery 1998; 43:670.

    Article  Google Scholar 

  24. St George EJ, Perks J, Plowman PN. Stereotactic radiosurgery XIV: the role of the haemosiderin “ring” in the development of adverse reactions following radiosurgery for intracranial cavernous malformations: a sustainable hypothesis. Br J Neurosurg 2002; 16(4):385–391.

    Article  CAS  PubMed  Google Scholar 

  25. Shih YH, Pan DH. Management of supratentorial cavernous malformations: craniotomy versus gammaknife radiosurgery. Clin Neurol Neurosurg 2005; 107(2):108–112.

    Article  PubMed  Google Scholar 

  26. Awad IA, Little JR, Akarawi WP, Ahl J. Intracranial dural arteriovenous malformations: factors predisposing to an aggressive neurological course. J Neurosurg 1990; 72(6):839–850.

    Article  CAS  PubMed  Google Scholar 

  27. Davies MA, TerBrugge K, Willinsky R, et al. The validity of classification for the clinical presentation of intracranial dural arteriovenous fistulas. J Neurosurg 1996; 85(5):830–837.

    Article  CAS  PubMed  Google Scholar 

  28. van Dijk JM, terBrugge KG, Willinsky RA, Wallace MC. Clinical course of cranial dural arteriovenous fistulas with long-term persistent cortical venous reflux. Stroke 2002; 33(5):1233–1236.

    Article  PubMed  Google Scholar 

  29. Satomi J, van Dijk JM, Terbrugge KG, et al. Benign cranial dural arteriovenous fistulas: outcome of conservative management based on the natural history of the lesion.[see comment]. J Neurosurg 2002; 97(4):767–770.

    Article  PubMed  Google Scholar 

  30. Pan DH, Chung WY, Guo WY, et al. Stereotactic radiosurgery for the treatment of dural arteriovenous fistulas involving the transverse-sigmoid sinus.[see comment]. J Neurosurg 2002; 96(5):823–829.

    Article  PubMed  Google Scholar 

  31. Barcia-Salorio JL, Soler F, Barcia JA, Hernandez G. Radiosurgery of carotid-cavernous fistulae. Acta Neurochir Suppl 1994; 62:10–12.

    CAS  PubMed  Google Scholar 

  32. Guo WY, Pan DH, Wu HM, et al. Radiosurgery as a treatment alternative for dural arteriovenous fistulas of the cavernous sinus. AJNR Am J Neuroradiol 1998; 19(6):1081–1087.

    CAS  PubMed  Google Scholar 

  33. Onizuka M, Mori K, Takahashi N, et al. Gamma knife surgery for the treatment of spontaneous dural carotid-cavernous fistulas. Neurol Med Chir (Tokyo) 2003; 43(10):477–482; discussion 482–483.

    Article  Google Scholar 

  34. Link MJ, Coffey RJ, Nichols DA, Gorman DA. The role of radiosurgery and particulate embolization in the treatment of dural arteriovenous fistulas. J Neurosurg 1996; 84(5):804–809.

    Article  CAS  PubMed  Google Scholar 

  35. Pollock BE, Nichols DA, Garrity JA, et al. Stereotactic radiosurgery and particulate embolization for cavernous sinus dural arteriovenous fistulae. Neurosurgery 1999; 45(3):459–466; discussion 466–467.

    Article  CAS  PubMed  Google Scholar 

  36. Friedman JA, Pollock BE, Nichols DA, et al. Results of combined stereotactic radiosurgery and transarterial embolization for dural arteriovenous fistulas of the transverse and sigmoid sinuses. J Neurosurg 2001; 94(6):886–891.

    Article  CAS  PubMed  Google Scholar 

  37. Wanebo JE, Lonser RR, Glenn GM, Oldfield EH. The natural history of hemangioblastomas of the central nervous system in patients with von Hippel-Lindau disease. J Neurosurg 2003; 98(1):82–94.

    Article  PubMed  Google Scholar 

  38. Slater A, Moore NR, Huson SM. The natural history of cerebellar hemangioblastomas in von Hippel-Lindau disease. AJNR Am J Neuroradiol 2003; 24(8):1570–1574.

    PubMed  Google Scholar 

  39. Conway JE, Chou D, Clatterbuck RE, et al. Hemangioblastomas of the central nervous system in von Hippel-Lindau syndrome and sporadic disease. Neurosurgery 2001; 48(1):55–62; discussion 63.

    Article  CAS  PubMed  Google Scholar 

  40. Chang SD, Meisel JA, Hancock SL, et al. Treatment of hemangioblastomas in von Hippel-Lindau disease with linear accelerator-based radiosurgery. Neurosurgery 1998; 43(1):28–34; discussion 35.

    Article  CAS  PubMed  Google Scholar 

  41. Jawahar A, Kondziolka D, Garces YI, et al. Stereotactic radiosurgery for hemangioblastomas of the brain. Acta Neurochir 2000; 142(6):641–644; discussion 644–645.

    Article  CAS  Google Scholar 

  42. Niemela M, Lim YJ, Soderman M, et al. Gamma knife radio surgery in 11 hemangioblastomas. J Neurosurg 1996; 85(4):591–596.

    Article  CAS  PubMed  Google Scholar 

  43. Pan L, Wang EM, Wang BJ, et al. Gamma knife radiosurgery for hemangioblastomas. Stereotact Funct Neurosurg 1998; 70(Suppl 1):179–186.

    Article  PubMed  Google Scholar 

  44. Patrice SJ, Sneed PK, Flickinger JC, et al. Radiosurgery for hemangioblastoma: results of a multiinstitutional experience. Int J Radiat Oncol Biol Phys 1996; 35(3):493–499.

    Article  CAS  PubMed  Google Scholar 

  45. Rajaraman C, Rowe JG, Walton L, et al. Treatment options for von Hippel-Lindau’s haemangioblastomatosis: the role of gamma knife stereotactic radiosurgery. Br J Neurosurg 2004; 18(4):338–342.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Neurosurgery, University of Illinois at Chicago, Chicago, IL, USA

    Sepideh Amin-Hanjani MD (Assistant Professor)

  2. Department of Neurosurgery, Harvard Medical School, USA

    Frederick G. Barker II MD (Assistant Professor and Associate Visiting Neurosurgeon)

  3. Brain Tumor Center, Massachusetts General Hospital, Boston, MA, USA

    Frederick G. Barker II MD (Assistant Professor and Associate Visiting Neurosurgeon)

Authors
  1. Sepideh Amin-Hanjani MD
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  2. Frederick G. Barker II MD
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Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Boston University School of Medicine, Boston, MA, USA

    Lawrence S. Chin MD (Professor and Chairman) (Professor and Chairman)

  2. Department of Radiation Oncology, University of Maryland Medical School, Baltimore, MD, USA

    William F. Regine MD (Professor and Chairman) (Professor and Chairman)

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Amin-Hanjani, S., Barker, F.G. (2008). Cavernous Malformations and Other Vascular Abnormalities: Observation-Alone Perspective. In: Chin, L.S., Regine, W.F. (eds) Principles and Practice of Stereotactic Radiosurgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-71070-9_51

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  • DOI: https://doi.org/10.1007/978-0-387-71070-9_51

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-71069-3

  • Online ISBN: 978-0-387-71070-9

  • eBook Packages: MedicineMedicine (R0)

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