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Mechanisms of transmitter release from astrocytes

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Astrocytes in (Patho)Physiology of the Nervous System

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Abbreviations

ABC:

ATP-binding cassette

AMPA:

a-amino-3-hydroxy-5-methyl-isoxazole propionate

ASCT:

alanine-serine-cysteine transporter

ATP:

adenosine 5′-triphosphate

BAPTA:

1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid

BBG:

Brilliant Blue G

BzATP:

3′-O-(4-benzoyl)benzoyl ATP

cAMP:

adenosine 3′:5′ cyclic monophosphate

CFTR:

cystic fibrosis transmembrane conductance regulator

cGMP:

guanosine 3′:5′ cyclic monophosphate

C m :

plasma membrane capacitance

Cx:

connexin

DIDS:

4,4′-diisothiocyanato-stilbene-2,2′-disulfonate

EGFP:

enhanced green fluorescent protein

EM:

electron microscopy

ENT:

equilibrative nucleoside transporters

EPSC:

excitatory post synaptic current

FFA:

flufenamic acid

GA:

18b-glycyrrhetinic acid

GABA:

g-amino butyric acid

GAD:

glutamic acid decarboxylase

GAT:

plasma membrane GABA transporter

GlyT:

plasma membrane glycine transporters

HCA:

homocysteic acid

MRP:

multidrug resistance protein

NKCC:

Na+-K+-Cl- cotransporters

NMDA:

N-methyl-d-aspartic acid

oATP:

oxidized ATP

PPADS:

pyridoxal phosphate-6-azophenyl-2-4-disulfonic acid

SNARE:

soluble N-ethyl maleimide-sensitive fusion protein attachment protein receptor

SOC:

slow outward current

TCA:

tricarboxylic acid

UDP:

uridine diphosphate-glucose

UTP:

uridine 5′-triphosphate

V-ATPase:

vacuolar type proton ATPase

VGAT:

vesicular GABA transporter

VGLUT:

vesicular glutamate transporter

VRAC:

volume-regulated anion channels

VSOR:

volume-sensitive outwardly rectifying

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Acknowledgments

The authors’ work is supported by a grant from the National Institute of Mental Health (R01 MH 069791). We thank Drs. Eliana Scemes and David C. Spray for comments on the previous versions of this manuscript.

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  1. Department of Neurobiology, Center for Glial Biology in Medicine, Civitan International Research Center, Atomic Force Microscopy & Nanotechnology Laboratories, Evelyn F. McKnight Brain Institute, University of Alabama, Birmingham, AL, USA

    Erik B. Malarkey & Vladimir Parpura

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    Malarkey, E., Parpura, V. (2009). Mechanisms of transmitter release from astrocytes. In: Haydon, P., Parpura, V. (eds) Astrocytes in (Patho)Physiology of the Nervous System. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-79492-1_12

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