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Antimicrobial Resistance in Enteric Pathogens in Developing Countries

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Antimicrobial Resistance in Developing Countries

Abstract

Bacterial enteric infections exact a heavy toll on human populations, particularly among children and immunosuppressed individuals in developing countries, where malnutrition, HIV/AIDS and poor sanitation abound. Despite the explosion of knowledge on the pathogenesis of enteric diseases during the past two decades, the number of diarrhoeal episodes and human deaths reported especially among the poor populations in developing countries remain of apocalyptic dimensions. With several studies from developing countries showing worrying trends in multiple resistance among key enteric pathogens such as Escherichia coli, Klebsiella, Salmonella spp., Vibrio cholerae and Shigella spp. to nearly all commonly available antibiotics, it is imperative that this trend should be reversed. Many countries in the developing world lack a formal surveillance system for antibiotic resistance and often treatment is given empirically based on clinical diagnosis alone. Availability of antibiotics over the counter without prescription has not helped either. To minimize the negative effect on public health, a concerted effort is required in surveillance, public health education and awareness of dangers of resistance, and a clear policy on procurement and prudent use of antibiotics in these resource-poor settings.

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References

  • Adeleye, I.A., and Adetosoye, A.I. 1993. Antimicrobial resistance patterns and plasmid survey of Salmonella and Shigella isolated is Ibadan, Nigeria. East Afr. Med. J. 70: 259–262.

    CAS  PubMed  Google Scholar 

  • Aidara, A., Koblavi, S., Boye, C.S., Raphenon, G., Gassama, A., Grimont, F., and Grimont, P.A.D. 1998. Phenotypic and genotypic characterization of Vibrio cholerae isolates from a recent cholera outbreak in Senegal: comparison with isolates from Guinea-Bissau. Am. J. Trop. Med. Hyg. 58: 163–167.

    CAS  PubMed  Google Scholar 

  • Anderson A.M., Varkey, J.B., Petti, C.A., Liddle, R.A., Frothingham, R., and Woods, C.W. 2004. Non-O1 Vibrio cholerae septicemia: case report, discussion of literature, and relevance to bioterrorism. Diagn. Microbiol. Infect. Dis. 49, 295–297.

    Article  PubMed  Google Scholar 

  • Asrat, D., Nilsson, I., Mengistu, Y., Ashenafi, S., Ayenew, K., Al-Soud, W.A., Wadstrom, T., and Kassa, E. 2004. Prevalence of Helicobacter pylori infection among adult dyspeptic patients in Ethiopia. Ann. Trop. Med. Parasitol. 98: 181–189.

    Article  CAS  PubMed  Google Scholar 

  • Bachou, H., Tylleskar, T., Kaddu-Mulindwa, D.H., and Tumwine, J.K. 2006. Bacteraemia among severely malnourished children infected and uninfected with the human immunodeficiency virus-1 in Kampala, Uganda. BMC Infect. Dis. 6: 160.

    Article  PubMed  Google Scholar 

  • Bartoloni, A., Benedetti, M., Pallecchi, L., Larsson, M., Mantella, A., Strohmeyer, M., Bartalesi, F., Fernandez, C., Guzman, E., Vallejos, Y., Villagran, A.L., Guerra, H., Gotuzzo, E., Paradisi, F., Falkenberg, T., Rossolini, G.M., and Kronvalli, G. 2006. Evaluation of a rapid screening method for detection of antimicrobial resistance in the commensal microbiota of the gut. Trans. Roy. Soc. Trop. Med. Hyg. 100: 119–25.

    Article  CAS  PubMed  Google Scholar 

  • Bii, C.C., Taguchi, H., Ouko, T.T., Muita, L.W., Wamae, N., and Kamiya, S. 2005. Detection of virulence-related genes by multiplex PCR in multidrug-resistant diarrhoeagenic Escherichia coli isolates from Kenya and Japan. Epidemiol. Infect. 133: 627–633.

    Article  CAS  PubMed  Google Scholar 

  • Berkley, J.A., Lowe, B.S., Mwangi, I., Williams, T., Bauni, E., Mwarumba, S., Ngetsa, C., Slack, M.P., Njenga, S., Hart, C.A., Maitland, K., English, M., Marsh, K., and Scott, J.A. 2005. Bacteremia among children admitted to a rural hospital in Kenya. New Engl. J. Med. 352: 39–47.

    Article  CAS  PubMed  Google Scholar 

  • Bejon, P., Mwangi, I., Ngetsa, C., Mwarumba, S., Berkley, J.A., Lowe, B.S., Maitland, K., Marsh, K., English, M., and Scott J.A. 2005. Invasive Gram-negative bacilli are frequently resistant to standard antibiotics for children admitted to hospital in Kilifi, Kenya. J. Antimicrob. Chemother. 56: 232–235.

    Article  CAS  PubMed  Google Scholar 

  • Borroto, R.J., and Martinez-Piedra, R. 2000. Geographical patterns of cholera in Mexico, 1991–1996. Int. J. Epidemiol. 29: 764–772.

    Article  CAS  PubMed  Google Scholar 

  • Brooks, J.T., Shapiro, R.L., Kumar, L., Wells, J.G., Phillips-Howard, P.A., Shi, Y.P., Vulule, J.M., Hoekstra, R.M., Mintz, E., and Slutsker, L. 2003. Epidemiology of sporadic bloody diarrhea in rural Western Kenya. Am. J. Trop. Med. Hyg. 68: 671–677.

    PubMed  Google Scholar 

  • Campos-Zahner, V., Avelar, K.E., Alves, R.M., Pereira, D.S., Vital, B.G., Freitas, F.S., Salles, C.S., and Karaolis, D.K. 2004. Genetic diversity and antibiotic resistance of clinical and environmental Vibrio cholerae suggests that many serogroups are reservoirs of resistance. Epidemiol. Infect. 135: 985–992.

    Article  Google Scholar 

  • Ceccarelli, D., Bani, S., Cappuccinelli, P., and Colombo, M.M. 2006. Prevalence of aadA1 and dfrA15 class 1 integron cassettes and SXT circulation in Vibrio cholerae O1 isolates from Africa. J. Antimicrob. Chemother. 58:1095–1107.

    Article  CAS  PubMed  Google Scholar 

  • Cheesbrough, J.S., Taxman, B.C., Green, S.D., Mewa, F.I., and Numbi, A. 1997. Clinical definition for invasive Salmonella infection in African children. Pediatr. Infect. Dis. J. 16, 277–83.

    Article  CAS  PubMed  Google Scholar 

  • Coovadia, A.Y.M., Gathiram, V., Bhamjee, A., Garratt, R.M., Mlisana, K., Pillay, N., Madlalose, T., and Short, M. 1992. An outbreak of multiresistant Salmonella typhi in South Africa. Q. J. Med. 82: 91–100.

    CAS  PubMed  Google Scholar 

  • Cooke, F.J., Wain, J., and Threlfall, E.J. 2006. Fluoroquinolone resistance in Salmonella Typhi. BMJ. 333:353–354.

    Article  PubMed  Google Scholar 

  • Crump, J.A., Luby S.P. and Mintz, E.D. 2004. The global burden of typhoid fever. Bull WHO 82, 346–353.

    PubMed  Google Scholar 

  • Dalsgaard, A., Mortensen, H. F., Mølbak, F., Dias, Serichantalergs, F., and Echeverria, P. 1996. Molecular characterization of Vibrio cholerae O1 strains isolated during cholera outbreaks in Guinea-Bissau. J. Clin. Microbiol. 34: 1189–1192.

    Google Scholar 

  • Duerink, D.O., Lestari, E.S., Hadi, U., Nagelkerke, N.D., Severin, J.A., Verbrugh, H.A., Keuter, M., Gyssens, I.C., and van den Broek, P.J. 2007. Determinants of carriage of resistant Escherichia coli in the Indonesian population inside and outside hospitals. J. Antimicrob. Chemother. 60: 377–384.

    Article  CAS  PubMed  Google Scholar 

  • Faruque, S.M., Chowdhury, N., Kamruzzaman, M., Dziejman, M., Rahman, M.H., Sack, D.A., Nair, G.B., and Mekalanos, J.J. 2004. Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area. Proc. Natl. Acad. Sci. USA 101:2123–2128.

    Google Scholar 

  • Fasano A., 2000. Intestinal infections: bacteria. In Pediatric Gastrointestinal Disease, ed. W.A. Walker, P. R. Durie, J. R. Hamilton. Ontario, BC Decker.

    Google Scholar 

  • Fica, A.E., Prat-Miranda, S., Fernandez-Ricci, A., D’Ottone, K., and Cabello, F.C. 1996. Epidemic typhoid in Chile: analysis by molecular and conventional methods of Salmonella typhi strain diversity in epidemic (1977 and 1981) and non-epidemic 1990 years. J. Clin. Microbiol. 34:1701–1707.

    CAS  PubMed  Google Scholar 

  • Glass, R.I., Huq, I., Alim, A.R. and Yunus, M. (1980) Emergence of multiply antibiotic-resistance Vibrio cholerae in Bangladesh. J. Infect. Dis. 142, 939–942.

    CAS  PubMed  Google Scholar 

  • Goma Epidemiology Group. 1995. Public health impact of the Rwandan refugee crisis: what happened in Goma, Zaire in July 1994? Lancet 345:359–361.

    Article  Google Scholar 

  • Graham, D.Y., Breiter, J.R., Ciociola, A.A., Sykes, D.L., and McSorley, D.J. 1998. An alternative non-macrolide, non-imidazole treatment regimen for curing Helicobacter pylori and duodenal ulcers: ranitidine bismuth citrate plus amoxicillin. The RBC H. pylori Study Group. Helicobacter 3:125–131.

    CAS  Google Scholar 

  • Graham, S.M. 2002. Salmonellosis in children in developing and developed countries and populations. Curr. Opin. Infect. Dis. 15:507–512.

    PubMed  Google Scholar 

  • Grenet, K. 2004. Antibacterial resistance, Wayampis amerindians, French Guyana. Emerg. Infect. Dis. 10:1150–1153.

    PubMed  Google Scholar 

  • Hart, C.A., and Kariuki, S. 1998. Antimicrobial resistance in developing countries. BMJ 317:649–650.

    Google Scholar 

  • Hirose, K., Hashimoto, A., Tamura, K., Kawamura, Y., Ezaki, T., Sagara, H., and Watanabe, H. 2002. DNA sequence analysis of DNA gyrase and DNA topoisomerase IV quinolone resistance-determining regions of Salmonella enterica serovar Typhi and serovar Paratyphi A. Antimicrob. Agents Chemother. 46:3249–3252.

    Article  CAS  PubMed  Google Scholar 

  • Hong, J., Kim, J.M., Jung, W.K., Kim, S.H., Bae, W., Koo, H.C., Gil, J., Kim, M., Ser, J., and Park, Y.H. 2007. Prevalence and antibiotic resistance of Campylobacter spp. isolated from chicken meat, pork, and beef in Korea, from 2001 to 2006. J. Food Prot. 70:860–866.

    CAS  PubMed  Google Scholar 

  • Itah, A.Y., and Uweh, E.E. 2005. Bacteria isolated from blood, stool and urine of typhoid patients in a developing country. Southeast Asian J. Trop. Med. Public Health 36:673–677.

    CAS  PubMed  Google Scholar 

  • Kaper, J.B., Morris, Jr, J.G. and Levine, M.M. 1995. Cholera. Clin. Microbiol. Rev. 8:48–86.

    Google Scholar 

  • Karaolis, D.K., Lan, R., and Reeves P.R. 1994. Molecular evolution of the seventh-pandemic clone of Vibrio cholerae and its relationship to other pandemic and epidemic V. cholerae isolates. J. Bacteriol. 1176:6199–6206.

    Google Scholar 

  • Kariuki, S., Muthotho, N., Kimari, J., Waiyaki, P., Hart, C.A., and Gilks, C.F. 1996. Molecular typing of multi-drug resistant Shigella dysenteriae type 1 by plasmid analysis and pulsed-field gel electrophoresis. Trans. Roy. Soc. Trop. Med. Hyg. 90:712–714.

    Article  CAS  PubMed  Google Scholar 

  • Kariuki, S., Gilks, C.F., Kimari, J., Muyodi, J., Waiyaki, P., and Hart, C.A. 1997. Plasmid diversity of multi-drug-resistant Escherichia coli isolated from children with diarrhoea in a poultry-farming area in Kenya. Ann. Trop. Med. Parasitol. 91:87–94.

    Article  CAS  PubMed  Google Scholar 

  • Kariuki, S., Gilks, C., Revathi, G. and Hart, C.A. 2000. Genotypic analysis of multidrug-resistant Salmonella enteric serovar Typhi, Kenya. Emerg. Infect. Dis. 6, 649–651.

    Google Scholar 

  • Kariuki, S., Corkill, J.E., Revathi, G., Musoke, R., and Hart, C.A. 2001. Molecular characterization of a novel plasmid encoded cefotaximase (CTX-M-12) found in clinical Klebsiella pneumoniae isolates from Kenya. Antimicrob. Agents Chemother. 45:2141–2143.

    Article  CAS  PubMed  Google Scholar 

  • Kariuki, S., Revathi, G., Muyodi, J., Mwituria, J., Munyalo, A., Mirza, S., and Hart, C.A. 2004. Characterization of multidrug-resistant typhoid outbreaks in Kenya. J. Clin. Microbiol. 42:1477–1482.

    Article  PubMed  Google Scholar 

  • Kariuki, S., Revathi, G., Kariuki, N., Kiiru, J., Mwituria, J., and Hart C.A. 2005. Increasing prevalence of multidrug-resistant non-typhoidal salmonellae, Kenya, 1994–2003. Int. J. Antimicrob. Agents 25:38–43.

    Article  CAS  PubMed  Google Scholar 

  • Kinana, A.D., Cardinale, E., Tall, F., Bahsoun, I., Sire, J.M., Garin, B., Breurec, S., Boye, C.S., and Perrier-Gros-Claude, J.D. 2006. Genetic diversity and quinolone resistance in Campylobacter jejuni isolates from poultry in Senegal. Appl. Environ. Microbiol. 72:3309–3313.

    Article  CAS  PubMed  Google Scholar 

  • Legros, D., Paquet, C., Dorlencourt, F., and Le Saoult, E. 1999. Risk factors for death in hospitalized dysentery patients in Rwanda. Trop. Med. Int. Health 4:428–432.

    Article  CAS  PubMed  Google Scholar 

  • Liu S.Y., Su L.H., Yeh Y.L., Chu C., Lai J.C., and Chiu C.H. 2007. Characterisation of plasmids encoding CTX-M-3 extended-spectrum beta-lactamase from Enterobacteriaceae isolated at a university hospital in Taiwan. Int J Antimicrob Agents. 29, 440–445.

    Google Scholar 

  • Lwai-Lume, L., Ogutu, E.O., Amayo, E.O., and Kariuki, S. 2004. Drug susceptibility pattern of Helicobacter pylori in patients with dyspepsia at the Kenyatta National Hospital, Nairobi. East Afr. Med. J. 82:603–608.

    Google Scholar 

  • Mohammed, R., and Kumar, S. 1991. Incidence of Campylobacter pylori in a consecutive series of surgical patients referred for endoscopy. J. R. Coll. Surg. Edinb. 36:422–423.

    CAS  PubMed  Google Scholar 

  • Misiewicz, J.J. 1995. Current insights in the pathogenesis of Helicobacter pylori infection. Eur. J. Gastroenterol. Hepatol. 7:701–703.

    CAS  PubMed  Google Scholar 

  • Mills-Robertson, F., Addy, M.E., Mensah, P., and Crupper, S.S. 2002. Molecular characterization of antibiotic resistance in clinical Salmonella typhi isolated in Ghana. FEMS Microbiol. Lett. 215:249–253.

    Article  CAS  PubMed  Google Scholar 

  • Mirza, S.H., Beeching, N.J., and Hart, C.A. 1996. Multidrug resistant typhoid: a global problem. J. Med. Microbiol. 44:317–319.

    Article  CAS  PubMed  Google Scholar 

  • Mhalu F.S., Mmari, P.W., and Ijumba, J. 1979. Rapid emergence of EI Tor Vibrio cholerae resistant to antimicrobial agents during first six months of fourth cholera in Tanzania. Lancet 1:345–347.

    Article  CAS  PubMed  Google Scholar 

  • Mutwewingabo, A., and Mets, T. 1987. Increase in multiresistance of Shigella dysenteriae type 1 strain in Rwanda. East Afr. Med. J. 64:812–815.

    CAS  PubMed  Google Scholar 

  • Nath, G., Tikoo, A., Manocha, H., Tripathi, A.K., and Gulati A.K. 2000. Drug resistance in Salmonella typhi in North India with special reference to ciprofloxacin. J. Antimicrob. Chemother. 46:149–150.

    Article  CAS  PubMed  Google Scholar 

  • Navia, M.M., Capitano, L., Ruiz, J., Vargas, M., Urassa, H., Schellemberg, D., Gascon, J., and Vila, J. 1999. Typing and characterization of mechanisms of resistance of Shigella spp. isolated from feces of children under 5 years of age from Ifakara, Tanzania. J. Clin. Microbiol. 37:3113–3117.

    CAS  PubMed  Google Scholar 

  • Nkemngu, N.J., Asonganyi, E.D., and Njunda, A.L. 2005. Treatment failure in a typhoid patient infected with nalidixic acid resistant S. enterica serovar Typhi with reduced susceptibility to ciprofloxacin: a case report from Cameroon. BMC Infect. Dis. 5:49.

    Article  PubMed  Google Scholar 

  • Nys, S., Okeke, I.N., Kariuki, S., Dinant, G.J., Driessen, C., and Stobberingh, E.E. 2004. Antibiotic resistance of faecal Escherichia coli from healthy volunteers from eight developing countries. J. Antimicrob. Chemother. 54:952–955.

    Article  CAS  PubMed  Google Scholar 

  • Ogutu, E.O., Kang'ethe, S.K., Nyabola, L., and Nyong'o, A. 1998. Endoscopic findings and prevalence of Helicobacter pylori in Kenyan patients with dyspepsia. East Afr. Med. J. 75:85–89.

    CAS  PubMed  Google Scholar 

  • Okeke, I. N., and Edelman, R. 2001. Dissemination of antibiotic-resistant bacteria across geographic borders. Clin. Infect. Dis. 33:364–369.

    Article  CAS  PubMed  Google Scholar 

  • Pitman, C., Amali, R., Kanyerere, H., Siyasiya, A., Phiri,S., Phiri, A., Chakanika, I., Kampondeni, S., Chintolo, F.E., Kachenje, E., and Squire, S.B. 1996. Bloody diarrhea of adults in Malawi: clinical features, infectious agents, and antimicrobial sensitivities. Trans. R. Soc. Trop. Med. Hyg. 90:284–287.

    Article  CAS  PubMed  Google Scholar 

  • Roasto, M., Juhkam, K., Tamme, T., Hörman, A., Häkkinen, L., Reinik, M., Karus, A., and Hänninen, M.L. 2007. High level of antimicrobial resistance in Campylobacter jejuni isolated from broiler chickens in Estonia in 2005 and 2006. J. Food Prot. 70:1940–1944.

    PubMed  Google Scholar 

  • Sack, A.D., Sack, R.B., Nair, G.B., and Siddique, A.K. 2004. Cholera. The Lancet 363:223–233.

    Article  CAS  Google Scholar 

  • Salim, A., Lan, R., and Reeves, R. 2005. Vibrio cholerae pathogenic clones. Emerg. Infect. Dis. 11:1758–1760.

    PubMed  Google Scholar 

  • Samie, A., Obi, C.L., Barrett, L.J., Powell, S.M., and Guerrant, R.L. 2007. Prevalence of Campylobacter species, Helicobacter pylori and Arcobacter species in stool samples from the Venda region, Limpopo, South Africa: Studies using molecular diagnostic methods. J. Infect. 54:558–566.

    Article  CAS  PubMed  Google Scholar 

  • Scrascia, M., Forcillo, M., Maimone, F., and Pazzani, C. 2003. Susceptibility to rifaximin of Vibrio cholerae strains from different geographical areas. J. Antimicrob. Chemother. 52:303–305.

    Article  CAS  PubMed  Google Scholar 

  • Segal, I., Ally, R., and Mitchell, H. 2001. Gastric cancer in sub-Saharan Africa. Eur. J. Cancer Prev. 10:479–482.

    Article  CAS  PubMed  Google Scholar 

  • Shukla, I., Tiwari, R., and Agrawal, M. 2004. Prevalence of extended spectrum -lactamase producing Klebsiella pneumoniae in a tertiary care hospital. Indian J. Med. Microbiol. 22:87–91.

    CAS  PubMed  Google Scholar 

  • Skalsky, J.A. 1995. Dyspepsia and Helicobacter pylori infection in rural south west Cameroon. Trop. Doct. 25:92.

    CAS  PubMed  Google Scholar 

  • Soge, O.O., Adeniyi, B.A., and Roberts, M.C. 2006. New antibiotic resistance genes associated with CTX-M plasmids from uropathogenic Nigerian Klebsiella pneumoniae. J. Antimicrob. Chemother. 58:1048–1053.

    Article  CAS  PubMed  Google Scholar 

  • Srikantiah, P., Girgis, F.Y., Luby, S.P., Jennings, G., Wasfy, M.O., Crump, J.A., Hoekstra, R.M., Anwer, M., and Mahoney, F.J. 2006. Population-based surveillance of typhoid fever in Egypt. Am. J. Trop. Med. Hyg. 74:114–119.

    PubMed  Google Scholar 

  • Sur, D., Ramamurthy, T., Deen, J., and Bhattacharya, S.K. 2004. Shigellosis: challenges & management issues. Indian J. Med. Res. 120:454–462.

    Google Scholar 

  • Su, L.H., Wu, T.L., Chia, J.H., Chu, C., Kuo, A.J., and Chiu, C.H. 2005. Increasing ceftriaxone resistance in Salmonella isolates from a university hospital in Taiwan. J. Antimicrob. Chemother. 55:846–852.

    Article  CAS  PubMed  Google Scholar 

  • Tarr, P.E., Kuppens, L., Jones, T.C., Ivanoff, B., Aparin, P.G., and Heymann, D.L. 1999. Considerations regarding mass vaccination against typhoid fever as an adjunct to sanitation and public health measures: potential use in an epidemic in Tajikistan. Am. J. Trop. Med. Hyg. 61:163–170.

    CAS  PubMed  Google Scholar 

  • Threlfall, E.J. 2000. Epidemic Salmonella typhimurium DT 104-a truly international multiresistant clone. J. Antimicrob. Chemother. 46:7–10.

    Article  CAS  PubMed  Google Scholar 

  • Torres, M.E., Pirez, M.C., Schelotto, F., Varela, G., Parodi, V., Allende, F., Falconi, E., Dell'Acqua, L., Gaione, P., Mendez, M.V., Ferrari, A.M., Montano, A., Zanetta, E., Acuna, A.M., Chiparelli, H., and Ingold, E. 2001. Etiology of children's diarrhea in Montevideo, Uruguay: associated pathogens and unusual isolates. J. Clin. Microbiol. 39:2134–2139.

    Article  CAS  PubMed  Google Scholar 

  • Touati A., Benallaoua S., Djoudi F., Madoux J., Brasme L., and De Champs, C. 2007. Characterization of CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli strains isolated from hospital environments in Algeria. Microb. Drug Resist. 13:85–89.

    Article  CAS  PubMed  Google Scholar 

  • van den Bogaard, A.E., and Stobberingh, E.E. 2000. Epidemiology of resistance to antibiotics. Links between animals and humans. Int. J. Antimicrob. Agents 14:327–335.

    Article  PubMed  Google Scholar 

  • van de Mortel, H.J., Jansen, E.J., Dinant, G.J., London, N., Palacios Pru, E., and Stobberingh, E.E. 1998. The prevalence of antibiotic-resistant faecal Escherichia coli in healthy volunteers in Venezuela. Infect. 26:292–297.

    Google Scholar 

  • Wain, J., Hoa, N.T., Chinh, N.T., Vinh, H., Everett, M.J., Diep, T.S., Day, N.P., Solomon, T., White, N.J., Piddock, L.J., and Parry, C.M. 1997. Quinolone-resistant Salmonella typhi in Viet Nam: molecular basis of resistance and clinical response to treatment. Clin. Infect. Dis. 25:1404–1410.

    Article  CAS  PubMed  Google Scholar 

  • Wise, R., Hart, T., Cars, O., Streulens, M., Helmuth, R., Huovinen, P., and Sprenger, M. 1998. Antimicrobial resistance is a major threat to public health. BMJ 317:609–610

    CAS  PubMed  Google Scholar 

  • World Health Organization. 1998. Use of quinolones in food animals and potential impact on human health. Report of a WHO meeting in Geneva. Switzerland.

    Google Scholar 

  • World Health Organization. 1999. Containing antimicrobial resistance: review of the literature and report of a WHO workshop on the development of a global strategy for the containment of antimicrobial resistance. Geneva, Switzerland.

    Google Scholar 

  • World Health Organization. 2000. WHO Report on Global Surveillance of Epidemic-prone Infectious Diseases. WHO/CDS/CSR/ISR/2000.1.

    Google Scholar 

  • World Health Organization. 2006. Background document: The diagnosis, treatment and prevention of typhoid fever. Geneva, Switzerland.

    Google Scholar 

  • Yang, Y.J., Huang, M.C., Wang, S.M., Wu, J.J., Cheng, C.P., and Liu, C.C. 2002. Analysis of risk factors for bacteremia in children with nontyphoidal Salmonella gastroenteritis. Eur. J. Clin. Microbiol. Infect. Dis. 21:290–293.

    Article  PubMed  Google Scholar 

  • Zaidi, M.B., Leon, V., Canche, C., Perez, C., Zhao, S., Hubert, S.K., Abbott, J., Blickenstaff, K., and McDermott, P.F. 2007. Rapid and widespread dissemination of multidrug-resistant blaCMY-2 Salmonella Typhimurium in Mexico. J. Antimicrob. Chemother. 60:398–401.

    Article  CAS  PubMed  Google Scholar 

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  1. Kenya Medical Research Institute (KEMRI), Centre for Microbiology Research, Nairobi, Kenya

    Samuel Kariuki

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Editors and Affiliations

  1. Advisor Alliance for the Prudent Use of, Tufts University, Kneeland St. 75, Boston, 02111, U.S.A.

    Aníbal de J. Sosa

  2. Dept. Zoology, Makerere University Kampala, Kampala, Uganda

    Denis K. Byarugaba

  3. Fundación Lusara, Playa Rosarito 353, Mexico, 08810, Mexico

    Carlos F. Amábile-Cuevas

  4. Depts. Laboratory Medicine, National Taiwan Univ. Hosp., Taipei, Taiwan R.O.C.

    Po-Ren Hsueh

  5. Centre for Microbiology Research, Kenya Medical Research Institute (KEMRI), Nairobi, 00100, Kenya

    Samuel Kariuki

  6. Dept. Biology, Haverford College, Lancaster Avenue 370, Haverford, 19041, U.S.A.

    Iruka N. Okeke

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Kariuki, S. (2010). Antimicrobial Resistance in Enteric Pathogens in Developing Countries. In: Sosa, A., Byarugaba, D., Amábile-Cuevas, C., Hsueh, PR., Kariuki, S., Okeke, I. (eds) Antimicrobial Resistance in Developing Countries. Springer, New York, NY. https://doi.org/10.1007/978-0-387-89370-9_11

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