Abstract
The inflammatory process is the series of responses by living tissues to injurious or potentially injurious stimuli. Following the recognition of a potentially harmful agent within the tissue, chemical messages are sent to the microvascular bed. The purpose of these messages is to promote a change in the local microenvironment such that plasma components and selected blood cells accumulate at the inflammatory focus. The functional role of this accumulation may be seen as a mechanism by which neutralisation and/or removal of the inflammatory stimulus occurs.
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Forrest, M.J., Jose, P.J., Williams, T.J. (1985). The Role of the Complement-derived Polypeptide C5a in Inflammatory Reactions. In: Higgs, G.A., Williams, T.J. (eds) Inflammatory Mediators. Satellite Symposia of the IUPHAR 9th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07834-9_10
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DOI: https://doi.org/10.1007/978-1-349-07834-9_10
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