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Human Papillomavirus Infections and Prospects for Vaccination

  • Chapter
Vaccine Intervention Against Virus-Induced Tumours

Abstract

The infectious aetiology of human warts was established in 1907 by Ciuffo1, who successfully induced warts in volunteers after injection of cell-free extracts from common warts (verrucae vulgares). Warts occur in man as well as in a wide variety of animals, including Bolivian side-neck turtles2, African gray parrots3 and Indian elephants4, among many other species. It appears that at least the majority of these papillomatous proliferations is caused by papillomaviruses. These viruses are regarded as a sub-group of the genus papovaviruses5, although they have very little in common with the polyomavirus sub-group. On the basis of structural features, the genomic organisation and biological characteristics, it would be justified to regard the papillomavirus group as an independent genus.

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Authors
  1. Harald zur Hausen
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Editor information

Editors and Affiliations

  1. Royal Postgraduate Medical School, Hammersmith Hospital, W12 0HS, London, UK

    J. M. Goldman (Consultant Physician) (Consultant Physician)

  2. University of Bristol Medical School, BS8 1TD, Bristol, UK

    M. A. Epstein (Professor of Pathology) (Professor of Pathology)

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© 1986 The Leukaemia Research Fund

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Hausen, H.z. (1986). Human Papillomavirus Infections and Prospects for Vaccination. In: Goldman, J.M., Epstein, M.A. (eds) Vaccine Intervention Against Virus-Induced Tumours. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-08243-8_5

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  • DOI: https://doi.org/10.1007/978-1-349-08243-8_5

  • Publisher Name: Palgrave Macmillan, London

  • Print ISBN: 978-1-349-08245-2

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