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Antenatal glucocorticoid treatment in the prevention of neonatal RDS

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The Surfactant System of the Lung
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Abstract

Antenatal glucocorticoid administration in order to prevent neonatal respiratory distress syndrome (RDS) has been an established regimen for over 15 years [1]. Use of such therapy is indicated in all cases in which premature delivery is expected or medical reasons require it [2]. Nevertheless, this treatment is only effective to a limited extent and, as before, a considerable number of premature children die of pulmonary complications. Therefore every obstetric unit has to re-evaluate the data in this particular field from time to time.

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References

  1. Liggins, G. C. and Howie, R. N. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics 1972; 50: 515.

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  2. Lorenz, U. Antepartale Lungenreifebestimmung durch Fruchtwasseranalyse, Berlin-Heidelberg-New York: Springer-Verlag, 1982.

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  3. Papageorgiou, A. N., Colle, E., Farri-Kostopoulos, E. and Gelfand, M. M. Incidence of respiratory distress syndrome following antenatal betamethasone: role of sex, type of delivery and prolonged rupture of membranes. Pediatrics 1981; 67: 614–17.

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© 1991 Macmillan Publishers Limited

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Ragosch, V., Lorenz, U., Arabin, B., Jürgens, S., Weitzel, H. (1991). Antenatal glucocorticoid treatment in the prevention of neonatal RDS. In: Cosmi, E.V., Di Renzo, G.C., Anceschi, M.M. (eds) The Surfactant System of the Lung. Palgrave, London. https://doi.org/10.1007/978-1-349-12553-1_11

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  • DOI: https://doi.org/10.1007/978-1-349-12553-1_11

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-1-349-12555-5

  • Online ISBN: 978-1-349-12553-1

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