Skip to main content

Electrophysiology Of The Axon

  • Chapter
Voltage-Sensitive Ion Channels
  • 1137 Accesses

Now that we have defined the problem of biological excitability, reviewed the informational structures of living organisms and perused the early history of animal electricity, it is time for us to get down to the specifics of electrophysiology, the study of the electrical behavior of cells, tissues and organs. We must follow this trail before we can descend to the molecular level.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Notes And References

  1. L.W. Williams, The Anatomy of the Common Squid, Loligo Pealii (Leseur), Leiden, 1909; John Z. Young, Cold Spring Harbor Symposia on Quantitative Biology 4: 1–6, 1936.

    Google Scholar 

  2. Michael R. Guevara, in Nonlinear Dynamics in Physiology and Medicine, edited by Anne Beuter, Leon Glass, Michael C. Mackey and Michèle S. Titcombe, 2003, 87–121. With kind permission of Springer Science and Business Media.

    Google Scholar 

  3. Kenneth S. Cole, Membranes, Ions, and Impulses, University of California, Berkeley, 1972, 145–148.

    Google Scholar 

  4. Reprinted from Ichiji Tasaki, Physiology and Electrochemistry of Nerve Fibers, Academic Press, New York, 1982, 37–64, by permission from Elsevier.

    Google Scholar 

  5. John A. Connor, in Molluscan Nerve Cells: From Biophysics to Behavior, edited by John Koester and John H. Byrne, Cold Spring Harbor Laboratory, 1980, 125–133.w

    Google Scholar 

  6. G. Marmont, J. Cell Comp. Physiol. 34: 351–382, 1949.

    Article  Google Scholar 

  7. K.S. Cole, Arch. Sci. Physiol. 3:253–258, 1949.

    Google Scholar 

  8. Cole, ref. 3, 325ff.

    Google Scholar 

  9. Irwin Singer and Ichiji Tasaki, in Biological Membranes: Physical Fact and Function, vol. 1, Academic Press, London, 1968, 347–410.

    Google Scholar 

  10. H. M. Fishman, Biophys. J. 10:799–817, 1970.

    Article  ADS  Google Scholar 

  11. Thomas G. Smith, Jr., in Koester and Byrne, Molluscan Nerve Cells: From Biophysics to Behavior, Cold Spring Harbor Laboratory, 1980, 135–143; Rodolfo Llinás, in Koester and Byrne, 145–155.

    Google Scholar 

  12. Thomas G. Smith, Jr., Jeffery L. Barker and Harold Gainer, Nature 253: 450–452, 1975; Smith, op. cit., 136.

    Article  Google Scholar 

  13. Douglas Junge, Nerve and Muscle Excitation, Sinauer Associates, Inc., Sunderland, MA, 1981, 115– 132.

    Google Scholar 

  14. J. J. B. Jack, D. Noble and R. W. Tsien, Electric Current Flow in Excitable Cells, Clarendon Press, Oxford, 1983, 305–378.

    Google Scholar 

  15. Tasaki, 114–129.

    Google Scholar 

  16. Anthony L. F. Gorman, Anton Hermann and Martin V. Thomas , in Koester and Byrne, Molluscan Nerve Cells: From Biophysics to Behavior, Cold Spring Harbor Laboratory, 1980, 169–180.

    Google Scholar 

  17. Reprinted from Constance Hammond, Cellular and Molecular Neurobiology, Academic Press, San Diego, 1996, 150, with permission from Elsevier.

    Google Scholar 

  18. A. L. Hodgkin and B. Katz, J. Physiol. 108:37–77, 1949; Constance Hammond., Cellular and Molecular Biology, Academic Press, San Diego, 1996, p. 119.

    Google Scholar 

  19. Tasaki, 140–143 and 216–218.

    Google Scholar 

  20. Tasaki, 211f.

    Google Scholar 

  21. Tasaki, 273.

    Google Scholar 

  22. S. Hagiwara and G. Yellen, in Koester and Byrne, Molluscan Nerve Cells: From Biophysics to Behavior, Cold Spring Harbor Laboratory, 1980, 33–40.

    Google Scholar 

  23. D. Tillotson, in Koester and Byrne, Molluscan Nerve Cells: From Biophysics to Behavior, Cold Spring Harbor Laboratory, 1980, 41–48.

    Google Scholar 

  24. H. Dieter Lux, in Koester and Byrne, Molluscan Nerve Cells: From Biophysics to Behavior, Cold Spring Harbor Laboratory, 1980, 105–114.

    Google Scholar 

  25. Floyd J. Brinley, in Koester and Byrne, Molluscan Nerve Cells: From Biophysics to Behavior, Cold Spring Harbor Laboratory, 1980, 73–80.

    Google Scholar 

  26. Roger C. Thomas, in Koester and Byrne, Molluscan Nerve Cells: From Biophysics to Behavior, Cold Spring Harbor Laboratory, 1980, 65–72.

    Google Scholar 

  27. Bertil Hille, Ion Channels of Excitable Membranes, Sinauer, Sunderland, Mass., 2001, 476f.

    Google Scholar 

  28. Tasaki, 232–255.

    Google Scholar 

  29. Hille, 63.

    Google Scholar 

  30. Hille, 396.

    Google Scholar 

  31. C. Y. Kao and S. E. Walker, J. Physiol. 323, 619, 1982.

    Google Scholar 

  32. Hille, 63.

    Google Scholar 

  33. Reprinted from Edward C. Conley and William J. Brammar, The Ion Channel FactsBook: Voltage Gated Channels, Academic, San Diego, 1999, 822, with permission from Elsevier.

    Google Scholar 

  34. Hille, 641 ff.

    Google Scholar 

  35. C. M. Armstrong, J. Gen. Physiol. 50:491–503, 1966; 54:553–575, 1969; 58:413–437, 1971.

    Article  Google Scholar 

  36. Hille, 65, 503–537.

    Google Scholar 

  37. Hille, 635–645.

    Google Scholar 

  38. J. Bernstein, Pflüg. Arch. ges. Physiol. 92:521, 1902.

    Article  Google Scholar 

  39. A. L. Hodgkin and B. Katz, J. Physiol. 109:240–249, 1949.

    Google Scholar 

  40. A. Krogh, Proc. Roy. Soc. B 133:140, 1946.

    Article  ADS  Google Scholar 

  41. C. S. Spyropoulos, J. gen. Physiol. 48:49–53, 1965.

    Article  Google Scholar 

  42. F. Kukita and S. Yamagishi, Biophys. J. 35:243, 1981.

    Article  Google Scholar 

  43. R. A. Chapman, Nature 213:1143–1144, 1967.

    Article  ADS  Google Scholar 

  44. Rita Guttman, in Biophysics and Physiology of Excitable Membranes, edited by W. J. Adelman Jr., Van Nostrand Reinhold, New York, 1971, 320–336.

    Google Scholar 

  45. Eric Jacobsson and Rita Guttman, in The Biophysical Approach to Excitable Systems, edited by William J. Adelman, Jr. and David E. Goldman, Plenum, New York, 1981, 197–211.

    Google Scholar 

  46. Y. Kobatake, in Membranes, Dissipative Structures, and Evolution, edited by G. Nicolis and R. Lefever, John Wiley, New York, 1975, 319–340.

    Google Scholar 

  47. Harvey M. Fishman, Biophys. J. 10:799–817, 1970.

    Article  Google Scholar 

  48. M. Eigen and L. de Maeyer, in Investigation of Rates and Mechanisms of Reactions, Part II, edited by S. L. Friess, E. S. Lewis and A. Weissberger, Interscience, New York, 1963, 895–1054.

    Google Scholar 

  49. L. E. Moore, J. P. Holt, Jr. and B. D. Lindley, Biophys. J. 12:157–174, 1972.

    Article  ADS  Google Scholar 

  50. Reprinted from L. E. Moore, Biochim. Biophys Acta 375:115–123, 1975, with permission from Elsevier.

    Article  Google Scholar 

  51. Y. Palti and W. J. Adelman, Jr., J. Membr. Biol. 1:431–458, 1969.

    Article  Google Scholar 

  52. C. S. Spyropoulos, J. Gen. Physiol. 48: 49–53, 1965.

    Article  Google Scholar 

  53. J. V. Howarth, R. D. Keynes and J. M. Ritchie, J. Physiol. 194:745–793, 1968.

    Google Scholar 

  54. I. Singer and I. Tasaki, in Biological Membranes: Physical Fact and Function, volume 1, edited by Dennis Chapman, Academic, London, 1968, 347–410.

    Google Scholar 

  55. L. B. Cohen and D. Landowne, in Biophysics and Physiology of Excitable Membranes, edited by W. J. Adelman Jr., Van Nostrand Reinhold, New York, 1971, 247–263.

    Google Scholar 

  56. Hervé Duclohier, J. Fluorescence 10:127–134, 2000.

    Article  Google Scholar 

  57. L. B. Cohen, R. D. Keynes and B. Hille, Nature (London) 218:438–441, 1968.

    Article  ADS  Google Scholar 

  58. Tasaki, 305.

    Google Scholar 

  59. Tasaki,308–310.

    Google Scholar 

  60. Hans-Christoph Lüttgau, Pflügers Archiv 262:244–255, 1956.

    Article  Google Scholar 

  61. J. M. Fox, Pflügers Archiv 351:287–301; 303–314, 1974.

    Article  Google Scholar 

  62. J. M. Fox, B. Neumcke, W. Nonner and R. Stämpfli, Pflügers Archiv 364:143–145, 1976.

    Article  Google Scholar 

  63. I. Tasaki and K. Iwasa, in Structure and Function in Excitable Cells, edited by D.C. Chang, I. Tasaki, W. J. Adelman, Jr. and H. R. Leuchtag, Plenum, N. Y., 1983, 307–319. With kind permission of Springer Science and Business Media.

    Google Scholar 

  64. K. Iwasa and I. Tasaki, Biochem. Biophys. Res. Comm. 95:1328–1331, 1980.

    Article  Google Scholar 

  65. Owen P. Hamill and Don W. McBride, Jr.,NIPS 9:53–59, 1994.

    Google Scholar 

Download references

Editor information

H. Richard Leuchtag

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2009). Electrophysiology Of The Axon. In: Leuchtag, H.R. (eds) Voltage-Sensitive Ion Channels. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5525-6_4

Download citation

Publish with us

Policies and ethics