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Crimean-Congo Hemorrhagic Fever in the Xinjiang Uygur Autonomous Region of Western China

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Crimean-Congo Hemorrhagic Fever

Certain regions of China are well known as Crimean-Congo hemorrhagic fever (CCHF)-endemic areas, particularly the western part of the Xinjiang Uygur Autonomous Region (Xinjiang) in western China. Xinjiang is unique in terms of CCHF virus (CCHFV) infections because this region forms the eastern boundary of CCHF endemic region and borders Pakistan, Afghanistan, Tajikistan, and Kyrgyzstan. These neighboring countries also have CCHFendemic areas. The study of CCHFV infections in this region can, therefore, provide important insights into CCHFV infections.

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References

  1. Ahmed AA, McFalls JM, Hoffmann C, Filone CM, Stewart SM, Paragas J, Khodjaev S, Shermukhamedova D, Schmaljohn CS, Doms RW, Bertolotti-Ciarlet A (2005) Presence of broadly reactive and group-specific neutralizing epitopes on newly described isolates of Crimean-Congo hemorrhagic fever virus. J Gen Virol 86:3327–3336.

    Article  PubMed  CAS  Google Scholar 

  2. Altaf A, Luby S, Ahmed AJ, Zaidi N, Khan AJ, Mirza S, McCormick J, Fisher-Hoch S (1998) Outbreak of Crimean-Congo haemorrhagic fever in Quetta, Pakistan: contact tracing and risk assessment. Trop Med Int Health 3:878–882.

    Article  PubMed  CAS  Google Scholar 

  3. Athar MN, Baqai HZ, Ahmad M, Khalid MA, Bashir N, Ahmad AM, Balouch AH, Bashir K (2003) Short report: Crimean-Congo hemorrhagic fever outbreak in Rawalpindi, Pakistan, February 2002. Am J Trop Med Hyg 69:284–287.

    PubMed  Google Scholar 

  4. Burney MI, Ghafoor A, Saleen M, Webb PA, Casals J (1980) Nosocomial outbreak of viral hemorrhagic fever caused by Crimean Hemorrhagic fever-Congo virus in Pakistan, January 1976. Am J Trop Med Hyg 29:941–947.

    PubMed  CAS  Google Scholar 

  5. Chinikar S, Persson SM, Johansson M, Bladh L, Goya M, Houshmand B, Mirazimi A, Plyusnin A, Lundkvist A, Nilsson M (2004) Genetic analysis of Crimean-Congo hemorrhagic fever virus in Iran. J Med Virol 73:404–411.

    Article  PubMed  CAS  Google Scholar 

  6. Hewson R, Gmyl A, Gmyl L, Smirnova SE, Karganova G, Jamil B, Hasan R, Chamberlain J, Clegg C (2004) Evidence of segment reassortment in Crimean-Congo haemorrhagic fever virus. J Gen Virol 85:3059–3070.

    Article  PubMed  CAS  Google Scholar 

  7. Iashina LN, Petrov VS, Petrova ID, Gutorov VV, Kazakov SV, Ospanov KS, Karimov SK, Tiunnikov GI, Seregin SV, Kuzina II, Babkin IV, Netesov SV (2002) Genetic identification of the Crimean-Congo hemorrhagic fever virus during epidemic outbreak in Kazakhstan in 2000. Mol Gen Mikrobiol Virusol 4:31–35.

    PubMed  Google Scholar 

  8. Iashina LN, Petrov VS, Vyshemirskii OI, Aristova VA, Moskvina TM, L'Vov DK, Petrova ID, Gutorov VV, Tiunnikov GI, Kuzina II, Samokhvlov EI, Seregin SV, Netesov SV (2002) Characteristics of Crimean-Congo hemorrhagic fever virus circulating in Russia and Central Asia. Vopr Virusol 47:11–15.

    PubMed  CAS  Google Scholar 

  9. Karti SS, Odabasi Z, Korten V, Yilmaz M, Sonmez M, Caylan R, Akdogan E, Eren N, Koksal I, Ovali E, Erickson BR, Vincent MJ, Nichol ST, Comer JA, Rollin PE, Ksiazek TG (2004) Crimean-Congo hemorrhagic fever in Turkey. Emerg Infect Dis 10:1379–1384.

    PubMed  Google Scholar 

  10. Khan AS, Maupin GO, Rollin PE, Noor AM, Shurie HH, Shalabi AG, Wasef S, Haddad YM, Sadek R, Ijaz K, Peters CJ, Ksiazek TG (1997) An outbreak of Crimean-Congo hemorrhagic fever in the United Arab Emirates, 1994–1995. Am J Trop Med Hyg 57:519–525.

    PubMed  CAS  Google Scholar 

  11. Li F (1983) Characteristics of Xinjiang hemorrhagic fever virus. III. Electron microscopic observation of Xinjiang hemorrhagic fever virus. Zhonghua Liu Xing Bing Xue Za Zhi 4:135–136.

    PubMed  CAS  Google Scholar 

  12. Lukashev AN (2005) Evidence for recombination in Crimean-Congo hemorrhagic fever virus. J Gen Virol 86:2333–2338.

    Article  PubMed  CAS  Google Scholar 

  13. Ma B, Hang C, Zhao Y, Wang S, Xie Y (2002) Use of a novel baculovirus vector to express nucleoprotein gene of Crimean-Congo hemorrhagic fever virus in both insect and mammalian cells. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 16:249–252.

    PubMed  CAS  Google Scholar 

  14. Morikawa S, Qing T, Xinqin Z, Saijo M, Kurane I (2002) Genetic diversity of the M RNA segment among Crimean-Congo hemorrhagic fever virus isolates in China. Virology 296:159–164.

    Article  PubMed  CAS  Google Scholar 

  15. Rodriguez LL, Maupin GO, Ksiazek TG, Rollin PE, Khan AS, Schwarz TF, Lofts RS, Smith JF, Noor AM, Peters CJ, Nichol ST (1997) Molecular investigation of a multisource outbreak of Crimean-Congo hemorrhagic fever in the United Arab Emirates. Am J Trop Med Hyg 57:512–518.

    PubMed  CAS  Google Scholar 

  16. Saijo M, Qing T, Niikura M, Maeda A, Ikegami T, Prehaud C, Kurane I, Morikawa S (2002) Recombinant nucleoprotein-based enzyme-linked immunosorbent assay for detection of immunoglobulin G antibodies to Crimean-Congo hemorrhagic fever virus. J Clin Microbiol 40:1587–1591.

    Article  PubMed  CAS  Google Scholar 

  17. Saijo M, Qing T, Niikura M, Maeda A, Ikegami T, Sakai K, Prehaud C, Kurane I, Morikawa S (2002) Immunofluorescence technique using HeLa cells expressing recombinant nucleoprotein for detection of immunoglobulin G antibodies to Crimean-Congo hemorrhagic fever virus. J Clin Microbiol 40:372–375.

    Article  PubMed  CAS  Google Scholar 

  18. Saijo M, Tang Q, Shimayi B, Han L, Zhang Y, Asiguma M, Tianshu D, Maeda A, Kurane I, Morikawa S (2004) Possible horizontal transmission of Crimean-Congo hemorrhagic Fever virus from a mother to her child. Jpn J Infect Dis 57:55–57.

    PubMed  Google Scholar 

  19. Saijo M, Tang Q, Shimayi B, Han L, Zhang Y, Asiguma M, Tianshu D, Maeda A, Kurane I, Morikawa S (2005) Antigen-capture enzyme-linked immunosorbent assay for the diagnosis of crimean-congo hemorrhagic fever using a novel monoclonal antibody. J Med Virol 77:83–88.

    Article  PubMed  CAS  Google Scholar 

  20. Saijo M, Tang Q, Shimayi B, Han L, Zhang Y, Asiguma M, Tianshu D, Maeda A, Kurane I, Morikawa S (2005) Recombinant nucleoprotein-based serological diagnosis of Crimean-Congo hemorrhagic fever virus infections. J Med Virol 75:295–299.

    Article  PubMed  Google Scholar 

  21. Sanchez AJ, Vincent MJ, Nichol ST (2002) Characterization of the glycoproteins of Crimean-Congo hemorrhagic fever virus. J Virol 76:7263–7275.

    Article  PubMed  CAS  Google Scholar 

  22. Schwarz TF, Nsanze H, Longson M, Nitschko H, Gilch S, Shurie H, Ameen A, Zahir AR, Acharya UG, Jager G (1996) Polymerase chain reaction for diagnosis and identification of distinct variants of Crimean-Congo hemorrhagic fever virus in the United Arab Emirates. Am J Trop Med Hyg 55:190–196.

    PubMed  CAS  Google Scholar 

  23. Tang Q, Gao D, Zhao X, Han L, Hang C (2002) Study on the molecular biology of hemorrhagic fever virus in Xinjiang. Zhonghua Liu Xing Bing Xue Za Zhi 23:449–452.

    PubMed  Google Scholar 

  24. Tang Q, Saijo M, Lei H, Niikura M, Maeda A, Ikegami T, Xinjung W, Kurane I, Morikawa S (2003) Detection of immunoglobulin G to Crimean-Congo hemorrhagic fever virus in sheep sera by recombinant nucleoprotein-based enzyme-linked immunosorbent and immunofluorescence assays. J Virol Methods 108:111–116.

    Article  CAS  Google Scholar 

  25. Tang Q, Saijo M, Zhang Y, Asiguma M, Tianshu D, Han L, Shimayi B, Maeda A, Kurane I, Morikawa S (2003) A patient with Crimean-Congo hemorrhagic fever serologically diagnosed by recombinant nucleoprotein-based antibody detection systems. Clin Diagn Lab Immunol 10:489–491.

    PubMed  CAS  Google Scholar 

  26. Tang Q, Zhao XQ, Wang HY, Simayi B, Zhang YZ, Saijo M, Morikawa S, Liang GD, Kurane I (2005) Molecular epidemiology of Xinjiang hemorrhagic fever viruses. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 19:312–318.

    PubMed  Google Scholar 

  27. van Eeden PJ, Joubert JR, van de Wal BW, King JB, de Kock A, Groenewald JH (1985) A nosocomial outbreak of Crimean-Congo haemorrhagic fever at Tygerberg Hospital. Part I. Clinical features. S Afr Med J 68:711–717.

    PubMed  Google Scholar 

  28. Yan YC (1983) Characteristics of Xinjiang hemorrhagic fever virus. II. Physicochemical properties of Xinjiang hemorrhagic fever virus. Zhonghua Liu Xing Bing Xue Za Zhi 4:132–134.

    PubMed  CAS  Google Scholar 

  29. Yan YC (1983) Studies on the characteristics of Xinjiang hemorrhagic fever virus. I. Serological relationship between Crimian-Congo hemorrhagic fever virus and Xinjiang hemorrhagic fever virus. Zhonghua Liu Xing Bing Xue Za Zhi 4:129–131.

    PubMed  CAS  Google Scholar 

  30. Yashina L, Petrova I, Seregin S, Vyshemirskii O, Lvov D, Aristova V, Kuhn J, Morzunov S, Gutorov V, Kuzina I, Tyunnikov G, Netesov S, Petrov V (2003) Genetic variability of Crimean-Congo haemorrhagic fever virus in Russia and Central Asia. J Gen Virol 84:1199–1206.

    Article  PubMed  CAS  Google Scholar 

  31. Yashina L, Vyshemirskii O, Seregin S, Petrova I, Samokhvalov E, Lvov D, Gutorov V, Kuzina I, Tyunnikov G, Tang YW, Netesov S, Petrov V (2003) Genetic analysis of Crimean-Congo hemorrhagic fever virus in Russia. J Clin Microbiol 41:860–862.

    Article  PubMed  CAS  Google Scholar 

  32. Yen YC, Kong LX, Lee L, Zhang YQ, Li F, Cai BJ, Gao SY (1985) Characteristics of Crimean-Congo hemorrhagic fever virus (Xinjiang strain) in China. Am J Trop Med Hyg 34:1179–1182.

    PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Virology 1, National Institute of Infectious Diseases, 4-7-1 Gakuen, Musashimurayama, 208-0011, Tokyo, Japan

    Masayuki Saijo M.D., Ph.D

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  1. Masayuki Saijo M.D., Ph.D
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Editors and Affiliations

  1. Marmara University, School of Medicine, Altunizade, Istanbul, Turkey

    Onder Ergonul M.D., M.P.H

  2. Usamriid, Fort Detrick, 21702-5011, Frederick, MD, USA

    Chris A. Whitehouse Ph.D

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© 2007 Springer

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Saijo, M. (2007). Crimean-Congo Hemorrhagic Fever in the Xinjiang Uygur Autonomous Region of Western China. In: Ergonul, O., Whitehouse, C.A. (eds) Crimean-Congo Hemorrhagic Fever. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6106-6_10

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