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Whole-Cell Phase Transition in Neurons and its Possible Role in Apoptotic Cell Death

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Phase Transitions in Cell Biology
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Abstract

For explanation of the formation of “dark” neurons, a non-enzymatic (physicochemical) mechanism, gel-to-gel phase transition, was recently hypothesized (Gallyas et al., Biol. Cell, 2004; 96:313–324). The present paper pieces together facts that support this mechanism, and draws attention to the possibility that the same physicochemical mechanism also plays a role in the execution phase of apoptosis.

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Gallyas, F., Pál, J. (2008). Whole-Cell Phase Transition in Neurons and its Possible Role in Apoptotic Cell Death. In: Pollack, G.H., Chin, WC. (eds) Phase Transitions in Cell Biology. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8651-9_5

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