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Radiation Biology of Tumor and Normal Tissues

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Evolution of Radiation Oncology at Massachusetts General Hospital

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Abstract

For the new department, the trustees wanted a program in laboratory research on the effects of radiation on animal cells and tissues, normal and malignant, and the whole organism.

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Notes

  1. 1.

    LD50 is the dose that is lethal to 50% of the irradiated mice.

  2. 2.

    γ 50 is the percent point increase in response probability for a 1% increase in dose.

  3. 3.

    TGF is the ratio of RBE tumor/RBE normal tissue.

  4. 4.

    TD50 is the number of cells that transplant tumor into half of the recipients.

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Authors and Affiliations

  1. Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA

    Herman D. Suit & Jay S. Loeffler

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  1. Herman D. Suit
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  2. Jay S. Loeffler
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Correspondence to Herman D. Suit .

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© 2011 Springer Science+Business Media, LLC

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Suit, H.D., Loeffler, J.S. (2011). Radiation Biology of Tumor and Normal Tissues. In: Evolution of Radiation Oncology at Massachusetts General Hospital. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6744-2_8

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  • DOI: https://doi.org/10.1007/978-1-4419-6744-2_8

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