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Clustering Studies for Identifying the Role of Environmental Factors in Aetiology of Human Cancers

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Environmental Factors, Genes, and the Development of Human Cancers

Abstract

This chapter reviews studies that have analysed clustering of cancer. In general, clustering studies may be divided into two distinct categories: (i) studies that are based on post hoc reports of unusual case aggregations; and (ii) studies that are based on rigorous and systematic analyses of population-based data. For each type of analysis, the underlying methodology is briefly described and key findings are summarised and interpreted in relation to putative aetiological factors.

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Acknowledgments

Childhood cancer epidemiology at Newcastle University is supported by the North of England Children’s Cancer Research Fund.

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  1. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK

    Richard J.Q. McNally

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  1. Richard J.Q. McNally
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Correspondence to Richard J.Q. McNally .

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  1. Robert Stempel School of Public Health, Dept. Environmental & Occupational Healt, Florida International University, SW. 8th Street 11200, Miami, 33199-0001, Florida, USA

    Deodutta Roy

  2. Robert Stempel College of Public Health, Department of Environmental and Occupati, Florida International University, Miami, 33199-0001, Florida, USA

    M. Tevfik Dorak

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McNally, R.J. (2010). Clustering Studies for Identifying the Role of Environmental Factors in Aetiology of Human Cancers. In: Roy, D., Dorak, M. (eds) Environmental Factors, Genes, and the Development of Human Cancers. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6752-7_4

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