Abstract
The skeleton is mesenchymal in origin. Most of its components pass through membranous and cartilaginous stages of development before becoming ossified, although in some parts there is only a membranous stage. These processes of endochondral and intramembranous ossification are well described in standard textbooks of histology.
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References
Acheson RM (1957) The Oxford method of assessing skeletal maturity. Clin Orthop 10: 19
Albright F, Scoville B, Sulkowitch HW (1938) Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and a gonadal dysfunction. Further observations including the report of two more cases. Endocrinology 22: 411
American Rheumatism Association (1977) [Proceedings of a symposium devoted to pediatric rheumatology.] Arthritis Rheum 20/2: [Suppl]
Ballet JP, Griscelli C, Coutris G, Milhaud G, Maroteaux P (1977) Bone marrow transplantation in osteopetrosis. Lancet 2: 1137
Basset F, Escaig J, Le Crom M (1972) A cytoplasmic membranous complex in histiocytosis X. Cancer 29: 1380
Bauze RJ, Smith R, Francis MJO (1975) A new look at osteogenesis imperfecta. J Bone Joint Surg [Br] 57: 2
Beighton P (1978) Inherited disorders of the skeleton. Churchill Livingstone, Edinburgh London New York (Genetics in medicine and surgery series)
Berry CL (1978) Drugs and the developing skeleton. Invest Cell Pathol 1: 129
Bonucci E, Sartori E, Spina M (1975) Osteopetrosis fetalis. Report on a case, with special reference to the ultrastructure. Virchows Arch [Pathol Anat] 368: 109
Boseker EH, Bickel WH, Dahlin DC (1968) A clinico-pathologic study of simple unicameral bone cysts. Surg Gynecol Obstet 127: 550
Byers PD (1968) Solitary benign osteoblastic lesions of bone. Osteoid osteoma and benign osteoblastoma. Cancer 22: 43
Chung SMK, Ralston EL (1969) Necrosis of the femoral head associated with sickle cell anaemia and its genetic variants. J Bone Joint Surg [Am] 51: 33
Cline MJ, Golde DW (1973) A review and re-evaluation of the histiocytic disorders. Am J Med 55: 49
Coccia PF, Krivit W, Cervenka, J, Clawson C, Kersey JH, Kim TH, Nesbit ME, Ramsay NKC, Warkentin PI, Teitelbaum SL, Kahn AJ, Brown DM (1980) Successful bone-marrow transplantation for infantile malignant osteopetrosis. N Engl J Med 302: 701
Cole ARC, Darte JMM (1963) Osteochondromata following irradiation in children. Pediatrics 32: 285
Collins DH (1966) Pathology of bone. Butterworths, London
Corrin B, Basset F (1979) A review of histiocytosis X with particular reference to eosinophilic granuloma of the lung. Invest Cell Pathol 2: 137
Cremin BJ, Beighton P (1978) Bone dysplasias of infancy. A radiological atlas. Springer, Berlin Heidelberg New York
Dabska M, Buraczewski J (1969) Aneurysmal bone cyst. Pathology, clinical course and radiologie appearances. Cancer 23: 371
Dahlin DC (1967) Chondromyxoid fibroma. In: Bone tumours, 2 edn. Thomas, Springfield Ill
Dahlin DC (1978) Bone tumours, 3rd edn. Thomas, Springfield Ill
Dahlin DC, Coventry MB (1967) Osteogenic sarcoma. A study of six hundred cases. J Bone Joint Surg [Am] 49: 101
Dahlin DC, Coventry MB, Scanlon PW (1961) Ewing’s sarcoma. A critical analysis of 165 cases. J Bone Joint Surg [Am] 43: 185
Dickson IR, Millar EA, Veis A (1975) Evidence for abnormality of bone matrix proteins in osteogenesis imperfecta. Lancet 2: 586
Eastoe JE, Martens P, Thomas NR (1973) The amino-acid composition of human hard tissue collagens in osteogenesis imperfecta and dentigenesis imperfecta. Calcif Tissue Res 12: 91
Elema JD, Poppema S (1978) Infantile histiocytosis X (Letterer-Siwe disease). Investigation with enzyme histochemical and sheep erythrocyte rosetting techniques. Cancer 42: 555
Ellis RWB, Van Creveld S (1940) A syndrome characterised by ectodermal dysplasia, polydactyly, chondroplasia and congenital morbus cardis. Arch Dis Child 15: 65
Fink CW, Dick VQ, Howard J, Nelson JD (1977) Infection of bone and joints in children. Arthritis Rheum 20 [Suppl 2]: 578
Flecker H (1942) The time of appearance and fusion of ossification centres as observed by roentgenographic methods. Am J Roentgenol 47: 97
Francis CC (1940) The appearance of centres of ossification from 6 to 15 years. Am J Phys Anthropol 27: 127
Francis CC, Werle PP (1939) The appearance of centres of ossification from birth to 5 years. Am J Phys Anthropol 24: 273
Friedman B, Gold H (1968) Ultrastructure of Ewing’s sarcoma of bone. Cancer 22: 307
Gitlow SE, Bertani LM, Rausen A, Gribetz O, Dziedzig SW (1970) Diagnosis of neuroblastoma by qualitative and quantitative determination of catecholamine metabolites in urine. Cancer 25: 1377
Gorodischer R, Davidson RG, Mosovich LL, Yaffe SJ (1976) Hypophosphatasia: a developmental anomaly of alkaline phosphase? Pediatr Res 10: 650
Harris WH, Dudley GR, Barry RJ (1962) The natural history of fibrous dysplasia. An orthopedic, pathological and roentgeographic study. J Bone Joint Surg [Am] 44: 207
Hass J (1951) Congenital dislocation of the hip. Thomas, Springfield Ill
Hayles AB, Dahlin DC, Coventry MB (1960) Osteogenic sarcoma in children. JAMA 174: 1174
Hwang WS, Tock EPC, Tan KL, Tan LKA (1979) The pathology of cartilage in chondrodysplasias. J Pathol 127: 11
Ibsen KH (1967) Distinct varieties of osteogenesis imperfecta. Clin Orthop 50: 279
Jaffe HL (1958) Tumors and tumorous conditions of the bones and joints. Lea and Febiger, Philadelphia
Jaffe HL (1972) Metabolic, degenerative and inflammatory diseases of bones and joints. Lea and Febiger, Philadelphia
Jaffe HL, Lichtenstein L (1948) Chondromyxoid fibroma of bone. A distinctive benign tumor likely to be mistaken especially for chondrosarcoma. Arch Pathol 45: 541
Jeffree GM, Price CHG (1965) Bone tumours and their enzymes. A study of the phosphatases, non-specific esterases and betaglucuronidase of osteogenic and cartilaginous tumours, fibroblastic and giant cell lesions. J Bone Joint Surg [Br] 47: 120
King JD, Bobechko WP (1971) Osteogenesis imperfecta. An orthopaedic description and surgical review. J Bone Joint Surg [Br] 53: 72
Kovac MH, Wolf JW, Thompson RC, Schwartz ER (1974) The biosynthetic rate and hydroxylysine content of collagen in osteogenesis imperfecta. J Bone Joint Surg [Am] 56: 859
Lennert K (1978) Malignant lymphomas. Springer, Berlin Heidelberg New York
Lichtenstein L (1965) Bone tumors. 3rd edn. Mosby, St. Louis
Lindbom A, Söderberg G, Spjut HT (1961) Osteogenic sarcoma. A review of 96 cases. Acta Radiol 56: 1
Llombart-Bosch A, Blache R, Pedro-Olaya A (1978) Ultrastructural study of 28 cases of Ewing’s sarcoma. Cancer 41: 1362
Lodwick GS (1958) Juvenile unicameral bone cyst. A roentgen reappraisal. Am J Roentgenol 80: 495
Loutit JF, Nesbit NW (1979) Resorption of bone. Lancet 2: 26
Matsuno T, Unni KK, McLeod RA, Dahlin DC (1976) Telangiectatic osteogenic sarcoma. Cancer 38: 2538
McKenna RJ, Schwinn CP, Soong KY, Higinbotham NL (1966) Sarcomata of the osteogenic series (osteosarcoma, fibrosarcoma, chondrosarcoma, parosteal osteogenic sarcoma, and sarcomata arising in abnormal bone). An analysis of 552 cases. J Bone Joint Surg [Am] 48: 1
McKusick VA, Egeland JA, Eldridge R, Krusen DE (1964) Dwarfism in the Amish. The Ellis-van Creveld syndrome. Bull Johns Hopkins Hosp 115: 306
Milhaud G, Labat M-L (1978) Thymus and osteopetrosis. Clin Orthop 135: 260
Milhaud G, Labat M-L, Graf B, Juster M, Balmain N, Moutier R, Toyama K (1975) Démonstration cinétique, radiographique et histologique de la guérison de l’ostéopétrose congénitale du rat. CR Acad Sci (Paris) [D] 280: 2485
Murphy FD, Blount WP (1962) Cartilaginous exostoses following irradiation. J Bone Joint Surg [Am] 44: 662
Neufeld EF (1974) The biochemical basis for mucopolysaccharidoses and mucolipidoses. Prog Med Genet 10: 81
Neufeld EF, Lim TW, Shapiro LJ (1975) Inherited disorders of lysosomal metabolism. Annu Rev Biochem 44: 357
Ochsner SF (1966) Eosinophilic granuloma of bone; experience with 20 cases. Am J Roentgenol 97: 719
Penttinen RP, Lichtenstein JR, Martin GR, McKusick VA (1975) Abnormal collagen metabolism in cultured cells in osteogenesis imperfecta. Proc Natl Acad Sci USA 72: 586
Phillips PE (1977) Viral arthritis in children. Arthritis Rheum 20 [Suppl 2]: 584
Pochaczesky R, Yen YM, Sherman RS (1960) The roentgen appearance of benign osteoblastoma. Radiology 75: 429
Ponseti IV (1978a) Growth and development of the acetabulum in the normal child. J Bone Joint Surg [Am] 60: 575
Ponseti IV (1978b) Morphology of the acetabulum in congenital dislocation of the hip. J Bone Joint Surg [Am] 60: 586
Ponseti IV, McClintock R (1956) The pathology of slipping of the upper femoral epiphysis. J Bone Joint Surg [Am] 38: 71
Rasmussen PG (1975) Multiple epiphyseal dysplasia. II. Morphological and histochemical investigation of cartilage matrix, particularly in the pre-calcification state. Acta Pathol Microbiol Scand [A] 83: 493
Reed RJ, Rothenberg M (1964) Lesions of bone that may be confused with aneurysmal bone cyst. Clin Orthop 35: 150
Rimoin DL, Silberberg R, Hollister PW (1976) Chondro-osseous pathology in the chondrodystrophies. Clin Orthop 114: 137
Schajowicz F (1959) Ewing’s sarcoma and reticulum cell sarcoma of bone with special reference to the histochemical demonstration of glycogen as an aid to differential diagnosis. J Bone Joint Surg [Am] 41: 349
Schajowicz F, Ackerman LV, Sissons HA (1972) Histological typing of bone tumours. International histological classification of tumours, no. 6. World Health Organization, Geneva
Schaller JG (1977) Arthritis of childhood onset. Clin Rheum Dis 3: 333
Scott CI (1976) Achondroplastic and hypochondroplastic dwarfism. Clin Orthop 114: 18
Selby S (1961) Metaphyseal defects in the tubular bones of growing children. J Bone Joint Surg [Am] 43: 395
Shapiro F, Glimcher MJ, Holtrop ME, Tashjian AH, Brickley-Parsons D, Kenzora JE (1980) Human osteopetrosis. J Bone Joint Surg [Am] 62: 284
Sillence DO, Horton WA, Rimoin DL (1979) Morphologic studies in the skeletal dysplasias. Am J Pathol 96: 813
Singer DB, Rudolph AJ, Rosenberg HS, Rawls WE, Boniuk M (1967) Pathology of the congenital rubella syndrome. J Pediatr 71: 665
Spjut HJ, Dorfman HD, Fechner RE, Ackerman LV (1970) Tumours of bone and cartilage. Armed Forces Institute of Pathology, Washington DC (Atlas of tumour pathology, 2nd ser, fasc 5)
Sutro CJ (1935) Slipping of the capital epiphysis of the femur in adolescence. Arch Surg 31: 345
Thomas LB, Forkner CE, Frei E, Besse BE, Stabenau JR (1961) The skeletal lesions of acute leukaemia. Cancer 14: 608
Vohra VG (1967) Roentgen manifestations of Ewing’s sarcoma. A study of 156 cases. Cancer 20: 727
Walker DG (1975) Bone resorption in osteopetrotic mice by transplants of normal bone marrow and spleen cells. Science 190: 784
Weinfeld MS, Dudley HR (1962) Osteogenic sarcoma. A follow up study of the ninety-four cases observed at the Massachusetts General Hospital from 1920–1960. J Bone Joint Surg [Am] 44: 269
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Revell, P.A. (1981). Diseases of Bones and Joints. In: Berry, C.L. (eds) Paediatric Pathology. Springer, London. https://doi.org/10.1007/978-1-4471-3304-9_10
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DOI: https://doi.org/10.1007/978-1-4471-3304-9_10
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