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Cerebral Blood Flow and Metabolism

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Care of the Critically Ill Patient

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Abstract

The brain relies on adequate delivery of O2 and glucose to maintain oxidative glycolysis and so provide energy [36]. With a reduction in O2 delivery, compensatory mechanisms maintain the physiological milieu. When these mechanisms are exhausted the brain is vulnerable to further insult. Enhancement of these compensatory mechanisms where possible could be a further aim of intensive therapy. This requires measurement of cerebral blood flow (CBF) but the spatial and temporal resolution of available techniques is insufficient to allow routine clinical measurement of CBF [30] and cerebral metabolic activity. When such measurements do become available it may be possible to recognize pathophysiological processes, instigate appropriate treatment, and predict prognosis.

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  1. R. E. Garlick
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Editors and Affiliations

  1. University of London, London WC1, UK

    Jack Tinker BSc, FRCP, FRCS, DIC (Dean of Postgraduate Medicine, Honorary Consultant Physician) (Dean of Postgraduate Medicine, Honorary Consultant Physician)

  2. The Middlesex Hospital, London W1, UK

    Jack Tinker BSc, FRCP, FRCS, DIC (Dean of Postgraduate Medicine, Honorary Consultant Physician) (Dean of Postgraduate Medicine, Honorary Consultant Physician)

  3. Harvard Medical School and Massachusetts General Hospital, 02114, Boston, Massachusetts, USA

    Warren M. Zapol MD (Professor of Anaesthesia) (Professor of Anaesthesia)

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Garlick, R.E. (1992). Cerebral Blood Flow and Metabolism. In: Tinker, J., Zapol, W.M. (eds) Care of the Critically Ill Patient. Springer, London. https://doi.org/10.1007/978-1-4471-3400-8_10

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  • DOI: https://doi.org/10.1007/978-1-4471-3400-8_10

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