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Clinical Trials: Handling the Data

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Success in Academic Surgery: Clinical Trials

Part of the book series: Success in Academic Surgery ((SIAS))

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Abstract

Randomized control trials (RCTs) provide the foundation for evidence-based medicine, which is the cornerstone of medical practice. RCTs are prospective studies that compare the effect of an intervention between an intervention and control group. An understanding of statistical methods is fundamental to the interpretation of RCT methods and results. This chapter will not provide an in-depth description of the methods of statistical analysis (this information can be obtained from any introductory statistics textbook). Instead, this chapter will provide a brief review of common statistical methods used to analyze data and discuss some issues associated with data analysis.

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Author information

Authors and Affiliations

  1. Department of Surgical Oncology, University of Texas, MD Anderson Cancer Center, 1400 Pressler Street, FCT 17.6060, 301402, Houston, TX, 77230-1402, USA

    Christina E. Bailey MD, MSCI & George J. Chang MD, MS

Authors
  1. Christina E. Bailey MD, MSCI
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  2. George J. Chang MD, MS
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Corresponding author

Correspondence to George J. Chang MD, MS .

Editor information

Editors and Affiliations

  1. Department of Surgery, Johns Hopkins, Baltimore, USA

    Timothy M. Pawlik

  2. Department of Surgery,, Duke University School of Medicine,, Durham, North Carolina, USA

    Julie A. Sosa

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© 2014 Springer-Verlag London

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Bailey, C.E., Chang, G.J. (2014). Clinical Trials: Handling the Data. In: Pawlik, T., Sosa, J. (eds) Success in Academic Surgery: Clinical Trials. Success in Academic Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-4679-7_4

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  • DOI: https://doi.org/10.1007/978-1-4471-4679-7_4

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4678-0

  • Online ISBN: 978-1-4471-4679-7

  • eBook Packages: MedicineMedicine (R0)

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