Abstract
The advent of directed mutagenesis has made it possible to alter protein structures at will. For the first time it is possible to design and to introduce modifications into a protein that are intended to change its behavior in predictable ways.
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Wozniak, J.A. et al. (1990). Crystallographic and Genetic Approaches Toward the Design of Proteins of Enhanced Thermostability. In: Bugg, C.E., Ealick, S.E. (eds) Crystallographic and Modeling Methods in Molecular Design. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3374-9_6
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DOI: https://doi.org/10.1007/978-1-4612-3374-9_6
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