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Hypoxia and Hypercapnia Deplete Clear Vesicles but Not Dense-Cored Vesicles in the Carotid Body’s Sensory Nerves

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Arterial Chemoreception

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Abstract

The nerves that terminate on the carotid body’s glomus cells have been a morphological curiosity since de Castro deduced that they have a sensory function (1), but it was not until the nerve endings were examined with the electron microscope that some of their most interesting features were recognized. One such feature is the presence of numerous 60-nm cytoplasmic vesicles, which resemble the synaptic vesicles of efferent (motor) nerves (2–4). Some of these vesicles cluster near morphologically typical synaptic junctions at which the nerves are presynaptic to glomus cells. Larger vesicles with electron-dense cores are also present in the nerve endings.

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Authors
  1. D. M. McDonald
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Editors and Affiliations

  1. Department of Physiology, University of Utah, School of Medicine, 84108, Salt Lake City, Utah, USA

    Carlos Eyzaguirre  & Sal J. Fidone  & 

  2. Department of Environmental Health Sciences, The Johns Hopkins Medical Institution, 21205, Baltimore, Maryland, USA

    Robert S. Fitzgerald

  3. Department of Physiology, School of Medicine, University of Pennsylvania, 19104-6085, Philadelphia, Pennsylvania, USA

    Sukhamay Lahiri

  4. Cardiovascular Research Institute, San Francisco Medical Center, University of California, 94143, San Francisco, California, USA

    Donald M. McDonald

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© 1990 Springer-Verlag New York Inc.

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McDonald, D.M. (1990). Hypoxia and Hypercapnia Deplete Clear Vesicles but Not Dense-Cored Vesicles in the Carotid Body’s Sensory Nerves. In: Eyzaguirre, C., Fidone, S.J., Fitzgerald, R.S., Lahiri, S., McDonald, D.M. (eds) Arterial Chemoreception. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3388-6_32

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  • DOI: https://doi.org/10.1007/978-1-4612-3388-6_32

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7993-8

  • Online ISBN: 978-1-4612-3388-6

  • eBook Packages: Springer Book Archive

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