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Antigen Society #13 Report (B7, B27, Bw47, Bw73): Six Subtypes of HLA-B7 Defined by Histotypes, Epitopes and 1D-IEF

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Immunobiology of HLA

Abstract

The HLA-B7 antigen was one of the best serologically defined HLA antigens in the Ninth Histocompatibility Workshop in 1984. Nevertheless, we could describe at least four different subtypes of the HLA-B7 antigen (*1). We now present data indicating a further heterogeneity of the HLA-B7 antigen as analyzed by HLA-B7 allospecific CTL clones, conventional pregnancy sera, and ID-IEF.

Reporting Laboratories: BENIVA,1 BENENG2

This study was supported by a grant from The Netherlands Kidney Foundation (grant no. 84502).

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References

  1. Van Seventer GA, Huis B, Melief CJM, Ivanyi P. Fine specificity of human HLA-B7-specific cytotoxic T-lymphocyte clones. I. Identification of HLA-B7 subtypes and histotopes of the HLA-B7 cross-reacting group. Hum Immunol 1986; 1375.

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  2. Reekers P, Van der Beucken M, Andrien M, Beelen J, Mueller-Eckhardt G, Schreuder GMTh. HLA-BPot: A new HLA antigen within the B7-cross-reactive group. Tissue Antigens 1986; 28: 182.

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  3. Taketani S, Krangel MS, Spits H, De Vries JE, Strominger JL. Structural analysis of an HLA-B7 antigen variant detected by cytotoxic T-lymphocytes. J Immunol 1984; 133: 816.

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© 1989 Springer-Verlag New York

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van Seventer, G.A. et al. (1989). Antigen Society #13 Report (B7, B27, Bw47, Bw73): Six Subtypes of HLA-B7 Defined by Histotypes, Epitopes and 1D-IEF. In: Dupont, B. (eds) Immunobiology of HLA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3552-1_35

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  • DOI: https://doi.org/10.1007/978-1-4612-3552-1_35

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8154-2

  • Online ISBN: 978-1-4612-3552-1

  • eBook Packages: Springer Book Archive

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