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Abstract

Relapsing fever (louseborne [epidemic] relapsing fever, tickborne [endemic] relapsing fever) is an acute febrile, septicemic illness of humans caused by spirochetes of the genus Borrelia. Borrelia recurrentis is the etiologic agent of louseborne relapsing fever and is transmitted by the body louse. The vectors of tickborne relapsing fever are the soft ticks, and a number of Borrelia species can be transmitted by these arthropods. The relapsing fevers are widely distributed in both tropical and temperate climates. Large epidemics of louseborne relapsing fever have occurred throughout Europe, Africa, Asia, and South America, and cases continue to be reported from African countries. Little is known about the worldwide incidence of tickborne relapsing fevers because of their sporadic occurrence.

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Literature Cited

  • Barbour, A. G., S. L. Tessier, and H. G. Stoenner. 1982. Variable major proteins of Borrelia hermsii. J. Exp. Med. 156:1312–1324.

    Article  PubMed  CAS  Google Scholar 

  • Boyer, K. M., R. S. Munford, G. O. Maupin, C. P. Pattison, M. D. Fox, A. M. Barnes, W. L. Jones, and J. E. Maynard. 1977. Tick-borne relapsing fever: an interstate outbreak originating at Grand Canyon National Park. Am. J. Epidemiol. 105:469–479.

    PubMed  CAS  Google Scholar 

  • Bryceson, A. D. M., E. H. O. Parry, P. L. Perine, D. A. Warrell, D. Vukotich, and C. S. Leithead. 1970. Louse-borne relapsing fever. A clinical and laboratory study of 62 cases in Ethiopia and a reconsideration of the literature. Quart. J. Med. 39:129–170.

    PubMed  CAS  Google Scholar 

  • Burgdorfer, W. 1976a. The diagnosis of the relapsing fevers, p. 225–234. In R. C. Johnson (ed.), The biology of parasitic spirochetes. Academic Press, Inc., New York.

    Google Scholar 

  • Burgdorfer, W. 1976b. The epidemiology of the relapsing fevers, p. 191–200. In R. C. Johnson (ed.), The biology of parasitic spirochetes. Academic Press, Inc., New York.

    Google Scholar 

  • Butler, T., P. K. Jones, C. K. Wallace. 1978. Borrelia recurrentis infection: single dose antibiotic regimens and management of Jarisch-Herxheimer reaction. J. Infect. Dis. 137:573–577.

    Article  PubMed  CAS  Google Scholar 

  • Butler, T., P. Hazen, C. K. Wallace, S. Awoke, and A. Habte-Michael. 1979. Infection with Borrelia recurrentis: pathogenesis of fever and petechiae. J. Infect. Dis. 140:665–675.

    Article  PubMed  CAS  Google Scholar 

  • Davis, G. E. 1956. The identification of spirochetes from human cases of relapsing fever by xenodiagnosis with comments on local specificity of tick vectors. Exp. Parasitol. 5:271–275.

    Article  PubMed  CAS  Google Scholar 

  • Felsenfeld, O. 1971. Borrelia. Strains, vectors, human and animal borreliosis. Warren H. Green, Inc., St. Louis.

    Google Scholar 

  • Fihn, S., E. B. Larson. 1980. Tick-borne relapsing fever in the Pacific Northwest: an underdiagnosed illness? West. J. Med. 133:203–209.

    PubMed  CAS  Google Scholar 

  • Fuchs, P. C., A. A. Oyama. 1969. Neonatal relapsing fever due to transplacental transmission of borrelia. J. Am. Med. Assoc. 208:690–692.

    Article  CAS  Google Scholar 

  • Hyde, F. W., R. C. Johnson. 1984. Genetic relationship of Lyme disease spirochetes to Borrelia, Treponema, and Leptospira. J. Clin. Microbiol. 20:151–154.

    PubMed  CAS  Google Scholar 

  • Hovind-Hougen, K. 1976. Treponema and Borrelia morphology, p. 7–28. In R. C. Johnson (ed.), The biology of parasitic spirochetes. Academic Press, Inc., New York.

    Google Scholar 

  • Johnson, R. C. 1981. Introduction to the spirochetes, p. 533–537. In M. P. Starr, H. Stolp, H. G. Truper, A. Balows, and H. G. Schlegel (eds.), The prokaryotes, a handbook on habitats, isolation and identification of bacteria. Springer-Verlag, New York.

    Google Scholar 

  • Kelly, R. 1971. Cultivation of Borrelia hermsi. Science 173:443.

    CAS  Google Scholar 

  • Kelly, R. T. 1976. Cultivation and physiology of relapsing fever borreliae, p. 87–94. In R. C. Johnson (ed.), The biology of parasitic spirochetes. Academic Press, Inc., New York.

    Google Scholar 

  • Kelly, R. T. 1984. Borrelia, p. 57–62. In N. R. Krieg and J. G. Hott (eds.), Bergey’s manual of systematic bacteriology. The Williams & Wilkins Co., Baltimore.

    Google Scholar 

  • Southern, P. M., J. P. Sanford. 1969. Relapsing fever. A clinical and microbiological review. Medicine 48:129–149.

    Google Scholar 

  • Stoenner, H. G., T. Dodd, C. Larsen. 1982. Antigenic variation of Borrelia hermsii. J. Exp. Med. 156:1312–1324.

    Article  PubMed  Google Scholar 

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© 1988 Springer-Verlag New York Inc.

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Johnson, R.C. (1988). Borelliosis (Relapsing Fever). In: Balows, A., Hausler, W.J., Ohashi, M., Turano, A., Lennete, E.H. (eds) Laboratory Diagnosis of Infectious Diseases. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3898-0_11

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  • DOI: https://doi.org/10.1007/978-1-4612-3898-0_11

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8393-5

  • Online ISBN: 978-1-4612-3898-0

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