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Differentiation as a Mechanism for Control of Malignancy in Human Cell Hybrids

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Tumor Cell Differentiation

Part of the book series: Experimental Biology and Medicine ((EBAM,volume 17))

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Abstract

The notion that aberrant cell differentiation is a consistent and important characteristic of malignant cells has been a popular theme in cancer research for many years. Theories concerning phenomena such as dedifferentiation, misprogramming of differentiated lineages, and inappropriate or ectopic expression of genes associated with embryonic development have often been linked to the progression of malignancy (1,2).

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Author information

Authors and Affiliations

  1. Microbiology and Molecular Genetics, University of California, Irvine, Irvine, California, USA

    Eric J. Stanbridge

Authors
  1. Eric J. Stanbridge
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Institute of Medical Biology, University of Tromsö, Tromsö, Norway

    Jarle Aarbakke

  2. Department of Applied Biochemistry, Walter Reed Army Institute of Research, Washington, DC, USA

    Peter K. Chiang

  3. University of California, Los Angeles, California, USA

    H. Phillip Koeffler

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© 1987 The Humana Press Inc.

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Stanbridge, E.J. (1987). Differentiation as a Mechanism for Control of Malignancy in Human Cell Hybrids. In: Aarbakke, J., Chiang, P.K., Koeffler, H.P. (eds) Tumor Cell Differentiation. Experimental Biology and Medicine, vol 17. Humana Press. https://doi.org/10.1007/978-1-4612-4594-0_22

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  • DOI: https://doi.org/10.1007/978-1-4612-4594-0_22

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8941-8

  • Online ISBN: 978-1-4612-4594-0

  • eBook Packages: Springer Book Archive

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