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Neural Tissues in Human Teratomas

  • Chapter
The Human Teratomas

Part of the book series: Contemporary Biomedicine ((CB,volume 3))

Abstract

The presence of neural tissues in human teratomas is of great clinicopathological value for the following reasons:

  1. 1.

    Neuroectodermal derivatives constitute one of the most commonly differentiated tissues in a teratoma. In practice, the majority of teratoid neoplasms yield neural tissues if adequately sampled (Willis, 1971).

  2. 2.

    The differentiation pattern of the nervous tissue found in teratomas is a good indicator of the overall maturity of the neoplasm. The current clinicopathological evaluations of teratomas are based on the amount of immature tissue, atypicality, and the proliferative capacity of embryonal tissues, especially of their neural components (Thurlbeck and Scully, 1960; Norris et al., 1976).

  3. 3.

    The presence of multiple neural elements and structures in different stages of ontogenesis mimics normal embryogenesis, and thus may shed some light on currently obscure embryological problems.

  4. 4.

    Large areas of neural tissue in immature teratomas resemble the morphology of common (glioma) and rare (medullo-epithelioma) tumors of the nervous system and can establish interrelations that may be of use in determining the histogenesis of some central nervous system tumors.

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Author information

Authors and Affiliations

  1. Department of Pathology, University of Granada Medical School, Granada, Spain

    Francisco F. Nogales Jr. & David Aguilar

Authors
  1. Francisco F. Nogales Jr.
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  2. David Aguilar
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Editor information

Editors and Affiliations

  1. Department of Pathology, Hahnemann Medical College and Hospital, Philadelphia, Pennsylvania, USA

    Ivan Damjanov

  2. The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA

    Davor Solter

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© 1983 The HUMANA Press Inc.

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Nogales, F.F., Aguilar, D. (1983). Neural Tissues in Human Teratomas. In: Damjanov, I., Knowles, B.B., Solter, D. (eds) The Human Teratomas. Contemporary Biomedicine, vol 3. Humana Press. https://doi.org/10.1007/978-1-4612-5628-1_7

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  • DOI: https://doi.org/10.1007/978-1-4612-5628-1_7

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-5630-4

  • Online ISBN: 978-1-4612-5628-1

  • eBook Packages: Springer Book Archive

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