Abstract
Techniques in vascular surgery and medicine have advanced considerably over the last decade. Whereas, in the past, critical ischaemia of the lower limb frequently resulted in amputation, nowadays, even lower limbs subject to occlusion of distal arteries can frequently be salvaged (Shah et al, 1992). Nonetheless, currently, of about 5000 patient visits per year to our Vascular Laboratory, some 100 of those patients with critical limb ischaemia (CLI) ultimately still need to undergo an amputation. Whether a below knee amputation is viable or not is currently predicted in our laboratory by means of skin blood flow measurements made at the site of the proposed skin flap (McCollum et al, 1985).
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References
Egglishaw, C, 1994 Quantification of catchment volumes of MCPD and EMPHO spectrophotometers, for visible wavelengths, using an in vivo model of the skin, Hons. Disstn., Dept. App. Phys. Elect, and Manuf. Eng., Univ. Dundee.
Harrison, D. K., and Walker, W. F., 1979, Microelectrode measurement of skin pH in humans during ischaemia, hypoxia and local hypothermia, J. Physiol. (Lond.) 291:339–350.
Harrison, D. K., Birkenhake, S., Hagen, N., and Kessler, M., 1989, Capillary blood flow and local oxygen supply in skeletal muscle during acute haemodilution with hydroxyethyl starch, Adv. Exp. Med. Biol. 248:693–698.
Harrison, D. K., Kessler, M., and Knauf, S. K., 1990, Regulation of capillary blood flow and oxygen supply in skeletal muscle in dogs during hypoxaemia, J. Physiol. (Lond.) 420:431–446.
Harrison, D. K., Evans, S. D., Abbot, N. C., Swanson Beck, J., and McCollum, P. T., 1992, Spectrophotometric measurements of haemoglobin saturation and concentration in skin during the tuberculin reaction in normal human subjects, Clin. Phys. & Physiol. Meas. 13:349–363.
Harrison, D. K., Abbot, N. C., Swanson Beck J., and McCollum, P. T., 1993, Preliminary assessment of laser Doppler imaging for measurement of skin perfusion using the tuberculin reaction in human skin as a model, Phys. Meas. 14:241–252.
Hickman, P., Walker, M.A., Harrison, D., Belch, J., and McCollum P.T,, 1992, Use of lightguide reflectance spectrophotometry in the assessment of peripheral arterial disease, Br. J. Surg. 79:361.
Kessler, M., Höper, J., Harrison, D. K., Skolasinska, K., Klövekorn, W. P., Sebening, F., Volkholz, H. J., Beier, I., Kernbach, C, Rettig, V., and Richter, H., 1984, Tissue 02 supply under normal and pathological conditions, Adv. Exp. Med. Biol. 169:69–80.
McCollum, P.T., Spence, V. A., and Walker, W. F., 1985, Circumferential skin blood flow measurements in the ischaemic limb, Br. J. Surg. 72:310–312.
McCollum, P. T., Spence, V. A., and Walker, W. F., 1988, Amputation for peripheral vascular disease: the case for level selection, Br. J. Surg. 75:1193–1195.
Shah, D. M., Darling, R. C. III., Chang, B. B., Kaufman, J. L., Fitzgerald, K. M., and Leather, R. P., 1992, Is long vein bypass from groin to ankle a durable procedure? An analysis of a ten-year experience, J. Vasc. Surg. 15:402–407.
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© 1996 Plenum Press, New York
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Harrison, D.K., Newton, D.J., McCollum, P.T., Jain, A.S. (1996). Lightguide Spectrophotometry for the Assessment of Skin Healing Viability in Critical Limb Ischaemia. In: Ince, C., Kesecioglu, J., Telci, L., Akpir, K. (eds) Oxygen Transport to Tissue XVII. Advances in Experimental Medicine and Biology, vol 388. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0333-6_5
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DOI: https://doi.org/10.1007/978-1-4613-0333-6_5
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