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Fumonisin B1-Immunological EffectsS

The Influence of FBI on the Early Stage of Immune Response

  • Chapter
Natural Toxins 2

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 391))

Abstract

Fumonisin B1 (FBI) (C34H59N015, Mol.wt.721) is classified as a Fusarium mycotoxin produced by some related species including F.moniliforme, F.proliferatum, F.anthophi-lum, F.dlamini, F.napiforme, and F.nygamai. These strains have been isolated in Australia, Austria, Brazil, Canada, China, Indonesia, Italy, Nepal, New Caledonia, Peru, the Philippines, Poland, South Africa, Thailand, and the USA [37,38,61,62,63]. Exposure occurs mainly through dietary consumption of contaminated corn.

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Abbreviations

Ab:

Antibody

Ag:

Antigen

APC:

antigen presenting cell

CD:

clasters of differentiation

CTL:

cytotoxic lymphocyte

FBI:

fumonisin BI

Ig:

immunoglobulin

IL:

interleukin

i.p.:

intraperitoneal injection

i.v.:

intravenous injection

LPS:

lipopolysaccharide

MLS:

mixed lymphocyte culture

MHC:

major histocompatibility complex

PFC:

plague forming cell

PHA:

phytohemagglutinin

PTK:

phosphotyrosine kinase

PTP:

phosphotyrosine phosphatase

PLC:

phospholipase C

PLD:

phopholipase D

SRBC:

sheep red blood cells

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  1. RAMS, Institute of Nutrition, 2/14 Ustinsky proezd, 109240, Moscow, Russian Federation

    E. A. Martinova

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  1. University of Massachusetts, Dartmouth, North Dartmouth, Massachusetts, USA

    Bal Ram Singh

  2. Colorado State University, Fort Collins, Colorado, USA

    Anthony T. Tu

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Martinova, E.A. (1996). Fumonisin B1-Immunological EffectsS. In: Singh, B.R., Tu, A.T. (eds) Natural Toxins 2. Advances in Experimental Medicine and Biology, vol 391. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0361-9_27

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  • DOI: https://doi.org/10.1007/978-1-4613-0361-9_27

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