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Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

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60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center

Abstract

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are B-cell lymphoproliferative disorders characterized by a proliferation of mature-appearing but functionally incompetent lymphocytes. The result of this proliferation is an accumulation of lymphocytes that progressively infiltrate the lymph nodes, bone marrow, liver, and spleen. CLL and SLL are classified by the World Health Organization as the same disease entity [1]. They are identical histologically and immunophenotypically, but their manifestation is different: CLL manifests primarily in peripheral blood or bone marrow and SLL in the lymph nodes.

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Author information

Authors and Affiliations

  1. Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 455, Houston, TX, 77030, USA

    Apostolia-Maria Tsimberidou

  2. Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Michael J. Keating

Authors
  1. Apostolia-Maria Tsimberidou
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  2. Michael J. Keating
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Corresponding author

Correspondence to Apostolia-Maria Tsimberidou .

Editor information

Editors and Affiliations

  1. Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, 77030, Texas, USA

    M. Alma Rodriguez

  2. Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, 77030, Texas, USA

    Ronald S. Walters

  3. Department of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, 77030, Texas, USA

    Thomas W. Burke

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Tsimberidou, AM., Keating, M.J. (2013). Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. In: Rodriguez, M., Walters, R., Burke, T. (eds) 60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5197-6_20

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  • DOI: https://doi.org/10.1007/978-1-4614-5197-6_20

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-5196-9

  • Online ISBN: 978-1-4614-5197-6

  • eBook Packages: MedicineMedicine (R0)

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