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Circadian Regulation of Kisspeptin in Female Reproductive Functioning

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Kisspeptin Signaling in Reproductive Biology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 784))

Abstract

Female reproductive functioning requires the precise temporal ­organization of numerous neuroendocrine events by a master circadian brain clock located in the suprachiasmatic nucleus. Across species, including humans, disruptions to circadian timing result in pronounced deficits in ovulation and fecundity. The present chapter provides an overview of the circadian control of female reproduction, underscoring the significance of kisspeptin as a key locus of integration for circadian and steroidal signaling necessary for the initiation of ovulation.

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Authors and Affiliations

  1. Department of Psychology and Helen Wills Neuroscience Institute, Neurobiology Laboratory, University of California, 3210 Tolman Hall, 1650, Berkeley, CA, 94720-1650, USA

    Lance J. Kriegsfeld Ph.D.

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  1. Lance J. Kriegsfeld Ph.D.
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Correspondence to Lance J. Kriegsfeld Ph.D. .

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  1. , Department of Reproductive Medicine, University of California, San Diego, La Jolla, 92093, California, USA

    Alexander S. Kauffman

  2. School of Anatomy, Physiology and Human Biology, The University of Western Australia, Hackett Drive, Nedlands, 6009, West Australia, Australia

    Jeremy T. Smith

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Kriegsfeld, L.J. (2013). Circadian Regulation of Kisspeptin in Female Reproductive Functioning. In: Kauffman, A., Smith, J. (eds) Kisspeptin Signaling in Reproductive Biology. Advances in Experimental Medicine and Biology, vol 784. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6199-9_18

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