Abstract
Autoimmune hepatitis (AIH) is considered the result of a loss of tolerance against one’s own liver tissue, probably triggered by external factors in genetically predisposed patients. The diagnosis is based on a combination of clinical, laboratory, and histologic features, as well as the exclusion of other disorders, as illustrated in Fig. 9.16. The histologic manifestations of AIH vary depending on the presentation (e.g., acute hepatitis; asymptomatic, discovered during routine laboratory tests; fulminant hepatitis; chronic liver disease). AIH usually responds to immunosuppressive therapy, and liver biopsy may be used to monitor the response to treatment and decide when to stop treatment.
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© 2014 Springer Science+Business Media New York
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Chan, A.W.H., Quaglia, A., Haugk, B., Burt, A. (2014). Autoimmune Hepatitis. In: Atlas of Liver Pathology. Atlas of Anatomic Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9114-9_9
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DOI: https://doi.org/10.1007/978-1-4614-9114-9_9
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