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Reconfiguration of the Central Respiratory Network Under Normoxic and Hypdxic Conditions

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Frontiers in Modeling and Control of Breathing

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 499))

Abstract

Apart from the obvious medical interest in understanding breathing, the respiratory rhythm is ideally suited for the study of state dependence and modifiability in central pattern generators (CPGs) in general. The list of variables with dramatic effects on breathing is impressive, including temperature, sleep/wake state, 02 and CO2 concentrations, airway irritation, conscious control, and a variety of pathological conditions. The ongoing breathing rhythm can be interrupted by coughing, sneezing, hiccoughing, swallowing, or vomiting; it can also be suspended in the post-inspiratory phase by vocalization. The pattern of breathing itself can take on several qualitatively distinct patterns, including eupneic (“normal”) breathing, panting, sighing, periodic breathing (during sleep), and gasping (in hypoxia).

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Authors and Affiliations

  1. Committee on Neurobiology and the Department of Organismal Biology and Anatomy, University of Chicago, Chicago, Illinois, 60637, USA

    Steven P. Lieske, Muriel Thoby-Brisson & Jan-Marino Ramirez

Authors
  1. Steven P. Lieske
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  2. Muriel Thoby-Brisson
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  3. Jan-Marino Ramirez
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Editor information

Editors and Affiliations

  1. Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

    Chi-Sang Poon

  2. Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA

    Homayoun Kazemi

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© 2001 Springer Science+Business Media New York

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Lieske, S.P., Thoby-Brisson, M., Ramirez, JM. (2001). Reconfiguration of the Central Respiratory Network Under Normoxic and Hypdxic Conditions. In: Poon, CS., Kazemi, H. (eds) Frontiers in Modeling and Control of Breathing. Advances in Experimental Medicine and Biology, vol 499. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1375-9_27

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  • DOI: https://doi.org/10.1007/978-1-4615-1375-9_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5522-9

  • Online ISBN: 978-1-4615-1375-9

  • eBook Packages: Springer Book Archive

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