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Structural Proteins of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

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Corona- and Related Viruses

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 380))

Abstract

PRRSV is a small, enveloped, RNA virus, which is similar to the arteriviruses in morphology, physicochemical properties, nucleotide sequence, genomic organization and replication strategy.1, 2, 3,4 The arteriviruses include lactate dehydrogenase-elevating virus (LDV), equine arteritis virus (EAV) and simian hemorrhagic fever virus (SHFV).5 Sequence information for the VR-2332,6 Lelystad3 and German isolates2 of PRRSV suggests the presence of 6 open reading frames (ORFs) that may code for structural proteins. Three putative, structural proteins have been identified for the VR-2332 isolate of PRRSV.7 However, additional structural proteins may exist and little information is available regarding the biochemical characteristics of these proteins. Therefore, the purpose of this study was to identify and conduct the initial characterization of the PRRSV structural proteins.

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Nelson, E.A., Christopher-Hennings, J., Benfield, D.A. (1995). Structural Proteins of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). In: Talbot, P.J., Levy, G.A. (eds) Corona- and Related Viruses. Advances in Experimental Medicine and Biology, vol 380. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1899-0_52

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  • DOI: https://doi.org/10.1007/978-1-4615-1899-0_52

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5775-9

  • Online ISBN: 978-1-4615-1899-0

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