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Regulation of Neural and Peripheral Cytokine Production by Benzodiazepines and Endogenous Anxiogenic Peptides

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In Vivo Immunology

Abstract

Our search to understand the molecular links between immune and nervous systems has led us to propose that central benzodiazepine receptors (CBR) and peripheral benzodiazepine receptors (PBR) could represent an integrative network whereby endogenous ligands could modulate anxiety as well as immune functions11.

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References

  1. V. Taupin, A. Herbelin, B. Descamps-Latscha, and F. Zavala, Endogenous anxiogenic peptide, ODN-diazepam binding inhibitor, and benzodiazepine influence monokine production, in: “Lymphatic Tissues and In Vivo Immune Response”, B.A. Imhof, S. Berrih-Aknin and S. Ezine, eds., Marcel Dekker, Inc., New York (1991)

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  2. V. Taupin, J. Gogusev, B. Descamps-Latscha, and F. Zavala, Modulation of TNFα, IL1β, IL6, IL8 and GM-CSF expression in human monocytes by an endogenous anxiogenic benzodiazepine ligand, triakonta-tetraneuropeptide: evidence for a role of prostaglandins. Mol Pharmacol. 43:64 (1993)

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  3. V. Taupin, S. Toulmond, A. Serrano, J. Benavides and F. Zavala; Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre-and post-traumatic treatment with Ro5-4864, a peripheral type (p site) benzodiazepine ligand. J. Neuroimmunol. 42:177 (1993)

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© 1994 Springer Science+Business Media New York

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Taupin, V., Toulmond, S., Benavides, J., Gogusev, J., Descamps-Latscha, B., Zavala, F. (1994). Regulation of Neural and Peripheral Cytokine Production by Benzodiazepines and Endogenous Anxiogenic Peptides. In: Heinen, E., Defresne, M.P., Boniver, J., Geenen, V. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 355. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2492-2_17

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  • DOI: https://doi.org/10.1007/978-1-4615-2492-2_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6062-9

  • Online ISBN: 978-1-4615-2492-2

  • eBook Packages: Springer Book Archive

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