Abstract
In the chick embryo, both mesoderm and endoderm are derived from a single germ layer, the epiblast, through the primitive streak, which is the first axial structure to develop. The streak arises after about 8 hours’ incubation, at stage 2 (Hamburger and Hamilton, 1951), as a thickening at the future caudal end of the blastoderm, just beneath the epiblast. It elongates cranially over the next 9 hours, while a groove appears along its length in the midline; cells migrate laterally from it to form the early mesoderm and the definitive (gut) endoderm. At the definitive streak stage (16–18 h of incubation; stage 4), the streak extends about three-quarters of the way across the area pellucida, with the primitive groove terminating rostrally in a pit. Anterior to this pit lies a mass of cells, termed Hensen’s node, after Viktor Hensen who first described it in 1876.
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Selleck, M.A.J., Stern, C.D. (1992). Evidence for Stem Cells in the Mesoderm of Hensen’s Node and Their Role in Embryonic Pattern Formation. In: Bellairs, R., Sanders, E.J., Lash, J.W. (eds) Formation and Differentiation of Early Embryonic Mesoderm. NATO ASI Series, vol 231. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3458-7_3
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DOI: https://doi.org/10.1007/978-1-4615-3458-7_3
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