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Adenosine and Cardiac Arrhythmias

  • Chapter
Cardiovascular Biology of Purines

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 209))

Summary

The negative chronotropic and dromotropic properties of adenosine on the sinus and atrioventricular (AV) nodes have been know since 1929 [Drury et al, 1929]. These potent properties and its short half life in vivo have allowed adenosine to establish its place as a unique and invaluable tool for both elucidating the mechanism of cardiac arrhythmias and for treating supraventricular tachycardia.

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Authors and Affiliations

  1. Division of Cardiology, Department of Medicine, The New York Hospital — Cornell Medical Center, New York, USA

    David J. Slotwiner MD & Bruce B. Lerman MD

Authors
  1. David J. Slotwiner MD
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  2. Bruce B. Lerman MD
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Editors and Affiliations

  1. Autonomic Neuroscience Institute, Royal Free and University College Medical School, London, UK

    Geoffrey Burnstock D. Sc.

  2. University of Massachusetts, USA

    James G. Dobson Jr. Ph. D.

  3. University of Pennsylvania, USA

    Bruce T. Liang M.D.

  4. University of Virginia, USA

    Joel Linden Ph. D.

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Slotwiner, D.J., Lerman, B.B. (1998). Adenosine and Cardiac Arrhythmias. In: Burnstock, G., Dobson, J.G., Liang, B.T., Linden, J. (eds) Cardiovascular Biology of Purines. Developments in Cardiovascular Medicine, vol 209. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5603-9_8

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