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Pressure Effects on Human Peripheral Nerve Function

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Tissue Nutrition and Viability

Abstract

The mechanism by which acute compression affects the function of peripheral nerve is not completely understood. The pathophysiology of nerve compression syndromes is related to both the magnitude and the duration of pressure. However, other factors such as nerve anatomy, systemic blood pressure and cardiovascular disease may modify the pressure-duration thresholds for nerve dysfunction. Recognition of these factors will have important implications for treatment of nerve compression lesions.

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References

  • Adamson JE, Srouji SJ, Horton CE and Mladick RA (1971). The acute carpal tunnel syndrome. Plast Reconstr Surg 47: 332–336.

    Article  PubMed  CAS  Google Scholar 

  • Bauman TD, Gelberman RH, Mubarak SJ and Garfin SR (1981). The acute carpal tunnel syndrome. Clin Orthop 156: 151–156.

    PubMed  Google Scholar 

  • Dahn I, Lassen NA and Westling H (1967). Blood flow in human muscles during external pressure or venous stasis. Clin Sci 32: 467–473.

    PubMed  CAS  Google Scholar 

  • Daniel CR, Bower JD, Pearson JE and Holbert RD (1974). Vibrometry and neuropathy. J Miss State Med Assoc 18: 30–34.

    Google Scholar 

  • Daniel CR, Bower JD, Pearson JE and Holbert RD (1977). Vibrometry and peripheral neuropathy. South Med J 70: 1311–1313.

    Article  PubMed  Google Scholar 

  • Dellon AL (1978). The moving two-point discrimination test: clinical evaluation of the quickly adapting fiber/receptor system. J Hand Surg 3: 474–481.

    CAS  Google Scholar 

  • Dellon AL (1980). Clinical use of vibratory stimuli to evaluate peripheral nerve injury and compression neuropathy. Plant Reconstr Surg 65: 466–476.

    Article  CAS  Google Scholar 

  • Dellon AL (1981). Evaluation of Sensibility and Re-education of Sensation in the Hand. Baltimore: Williams & Wilkins, pp. 95–167.

    Google Scholar 

  • Dellon AL, Curtis RM and Edgerton MT (1972). Evaluating recovery of sensation in the hand following nerve injury. Johns Hopkins Med J 130: 235–243.

    PubMed  CAS  Google Scholar 

  • Gelberman RH, Hergenroeder PT, Hargens AR, Lundborg GN and Akeson WH (1981). The carpal tunnel syndrome. A study of carpal tunnel pressures. J Bone Joint Surg 63A: 380–383.

    PubMed  CAS  Google Scholar 

  • Gelberman RH, Szabo RM, Williamson RV and Dimick MP (1983a). Sensibility testing in peripheral-nerve compression syndromes: an experimental study in humans. J Bone Joint Surg 65A: 632–638.

    PubMed  CAS  Google Scholar 

  • Gelberman RH, Szabo RM, Williamson RV, Hargens AR, Yaru NC and MinteerConvery MA (1983b). Tissue pressure threshold for peripheral nerve viability. Clin Orthop 178: 285–291.

    PubMed  Google Scholar 

  • Gelberman RH, Urbaniak JR, Bright DS and Levin LS (1978). Digital sensibility following replantation. J Hand Surg 3: 313–319.

    CAS  Google Scholar 

  • Hargens AR, Mubarak SJ, Owen CA, Garetto LP and Akeson WH (1977). Interstitial fluid pressure in muscle and compartment syndromes in man. Microvasc Res 14: 1–10.

    Article  PubMed  CAS  Google Scholar 

  • Hargens AR, Romine JS, Sipe JC, Evans KL, Mubarak SJ and Akeson WH (1979). Peripheral nerve-conduction block by high muscle-compartment pressure. J Bone Joint Surg 61A: 192–200.

    PubMed  CAS  Google Scholar 

  • Hargens AR, Schmidt DA, Evans KL, Gonsalves MR, Cologne JB, Garfin SR, Mubarak SJ, Hagen PL and Akeson WH (1981). Quantitation of skeletal-muscle necrosis in a model compartment syndrome. J Bone Joint Surg 63A: 631–636.

    PubMed  CAS  Google Scholar 

  • Hunter JM, Schneider LH, Mackin EJ and Bell JA (1978). Rehabilitation of the Hand. St. Louis: CV Mosby, pp. 273–291.

    Google Scholar 

  • Levin S, Pearsell G and Ruderman RJ (1978). Von Frey’s method of measuring pressure sensibility in the hand: an engineering analysis of the Weinstein-Semmes pressure aesthesiometer. J Hand Surg 3: 211–216.

    CAS  Google Scholar 

  • Lewis T (1936). Effects of circulatory arrest. In: Vascular Disorders of the Limbs, 2nd ed. London: Macmillan, pp. 17–25.

    Google Scholar 

  • Lewis T, Pickering GW and Rothschild P (1931). Centripetal paralysis arising out of arrested blood flow to a limb. Including notes on a form of tingling. Heart 16: 1–32.

    Google Scholar 

  • Lundborg G (1970). Ischemic nerve injury. Experimental studies on intraneural microvascular pathophysiology and have function in the limb subjected to temporary circulatory arrest. Scand J Plast Reconstr Surg (Suppl) 6: 1–113.

    Google Scholar 

  • Lundborg G (1975). Structure and function of the intraneural microvessels as related to trauma, edema formation and nerve function. J Bone Joint Surg 57A: 938–949.

    PubMed  CAS  Google Scholar 

  • Lundborg G, Gelberman RH, Minteer-Convery M, Lee YF and Hargens AR (1982). Median nerve compression in the carpal tunnel-functional response to experimentally induced controlled pressure. J Hand Surg 7: 252–259.

    CAS  Google Scholar 

  • Lundborg G, Myers R and Powell H (1983). Nerve compression injury and increased endoneurial fluid pressure: a “miniature compartment syndrome.” J Neurol Neurosurg Psychiatry 46: 1119–1124.

    Article  PubMed  CAS  Google Scholar 

  • Manual of Orthopedic Surgery (1972). Chicago: American Orthopaedic Association.

    Google Scholar 

  • Matsen FA III and Krugmire RB Jr (1978). Compartmental syndromes. Surg Gynecol Obstet 147: 943–949.

    PubMed  Google Scholar 

  • Matsen FA III, Mayo KA, Krugmire RB Jr, Sheriden GW and Kraft GH (1977). A model compartmental syndrome in man with particular reference to the quantification of nerve function. J Bone Joint Surg 59A: 648–653.

    PubMed  Google Scholar 

  • Matsen FA III, Mayo KA, Sheriden GW and Krugmire RB Jr (1976). Monitoring of intramuscular pressure. Surgery 79: 702–709.

    PubMed  Google Scholar 

  • Moberg E (1958). Objective methods for determining the functional value of sensibility in the hand. J Bone Joint Surg 40B: 454–476.

    Google Scholar 

  • Moberg E (1962). Criticism and study of methods for examining sensibility in the hand. Neurology 12: 8–19.

    PubMed  CAS  Google Scholar 

  • Moberg E (1964). Evaluation and management of nerve injuries in the hand. Surg Clin North Am 44: 1019–1029.

    PubMed  CAS  Google Scholar 

  • Moberg E (1966). Method for examining sensibility of the hand. In: Hand Surgery. Flynn JE (ed.). Baltimore: Williams & Wilkins, pp. 435–449.

    Google Scholar 

  • Mountcastle VB (1980). Medical Physiology, 14th ed. St Louis: CV Mosby, Chap-ter 11.

    Google Scholar 

  • Mubarak SJ and Hargens AR (1981). Compartment Syndromes and Volkmann’s Contracture. Philadelphia: WB Saunders, pp. 1–232.

    Google Scholar 

  • Mubarak SJ, Owen CA, Hargens AR, Garretto LP and Akeson WH (1978). Acute compartment syndromes: diagnosis and treatment with the aid of the wick catheter. J Bone Joint Surg 60A: 1091–1095.

    PubMed  CAS  Google Scholar 

  • Nielson VK and Kardel T (1974). Decremental conduction in normal human nerves subjected to ischemia? Acta Physiol Scand 92: 249–262.

    Article  Google Scholar 

  • Ochoa J, Fowler TJ and Gilliatt RW (1972). Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet. J Anat 113: 433–455.

    PubMed  CAS  Google Scholar 

  • Omer GE Jr (1974). Injuries to nerves of the upper extremity. J Bone Joint Surg 56A: 1615–1624.

    PubMed  Google Scholar 

  • Omer GE Jr (1980). Sensibility testing. In: Management of Peripheral Nerve Problems. GE Omer Jr and M Spinner (eds.). Philadelphia: WB Saunders, pp. 3–15.

    Google Scholar 

  • Paul RL, Goodman H and Merzenich M (1972). Alterations in mechanoreceptor input to Brodmann’s areas one and three of the postcentral hand area of Ma-caca mulatta after nerve section and regeneration. Brain Res 39: 1–19.

    Article  PubMed  CAS  Google Scholar 

  • Phalen GS (1972). The carpal-tunnel syndrome. Clinical evaluation of 598 hands. Clin Orthop 83: 29–40.

    Article  PubMed  CAS  Google Scholar 

  • Rorabeck CH, Macnab I, and Waddell JP (1972). Anterior tibial compartment syndrome: a clinical and experimental review. Can J Surg 15: 249–256.

    Google Scholar 

  • Rydevik B and Lundborg G (1977). Permeability of intraneural microvessels and perineurium following acute, graded experimental nerve compression. Scand J Plast Reconstr Surg 11: 179–187.

    Article  PubMed  CAS  Google Scholar 

  • Rydevik B, Lundborg G and Bagge U (1981). Effects of graded compression on intraneural blood flow. An in vivo study on rabbit tibial nerve. J Hand Surg 6: 3–12.

    CAS  Google Scholar 

  • Sheridan GW and Matsen FA III (1975). An animal model of the compartmental syndrome. Clin Orthop 113: 36–42.

    Article  PubMed  Google Scholar 

  • Spinner M (1978). Injuries to the Major Branches of the Forearm, 2nd ed. Philadelphia: WB Saunders.

    Google Scholar 

  • Sunderland S (1976). The nerve lesion in the carpal tunnel syndrome. J Neurol Neurosurg Psychiatry 39: 615–626.

    Article  PubMed  CAS  Google Scholar 

  • Sunderland S (1978). Nerves and Nerve Injuries, 2nd ed. Edinburgh: ES Livingstone.

    Google Scholar 

  • Szabo RM, Gelberman RH, Williamson RV, Dellon AL, Yaru NC and Dimick MP (1984). Vibratory sensory testing in acute peripheral nerve compression. J Hand Surg 9A: 104–109.

    Google Scholar 

  • Szabo RM, Gelberman RH, Williamson RV and Hargens AR (1983). Effects of increased systemic blood pressure on the tissue fluid pressure threshold of peripheral nerve. J Orthop Res 1: 172–178.

    Article  PubMed  CAS  Google Scholar 

  • Werner JL and Omer GE Jr (1970). Evaluating cutaneous pressure sensation of the hand. Am J Occup Ther 24: 347–356.

    PubMed  CAS  Google Scholar 

  • Whitesides TE Jr, Haney TC, Harada H, Holmes HE and Morimoto K (1975a). A simple method for tissue pressure determination. Arch Surg 110: 1311–1313.

    Article  PubMed  Google Scholar 

  • Whitesides TE Jr, Haney TC, Morimoto K and Harada H (1975b). Tissue pressure measurements as a determinant for the need of fasciotomy. Clin Orthop 113: 43–51.

    Article  PubMed  Google Scholar 

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Authors
  1. Richard H. Gelberman
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  2. Robert M. Szabo
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  3. Alan R. Hargens
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Editor information

Editors and Affiliations

  1. Division of Orthopaedics and Rehabilitation, University of California, 92093, San Diego, La Jolla, California, USA

    Alan R. Hargens (Professor of Surgery) (Professor of Surgery)

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© 1986 Springer-Verlag New York Inc.

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Gelberman, R.H., Szabo, R.M., Hargens, A.R. (1986). Pressure Effects on Human Peripheral Nerve Function. In: Hargens, A.R. (eds) Tissue Nutrition and Viability. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-0629-0_8

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  • DOI: https://doi.org/10.1007/978-1-4684-0629-0_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-0631-3

  • Online ISBN: 978-1-4684-0629-0

  • eBook Packages: Springer Book Archive

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