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Some Aspects of DNA Strand Separation

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DNA Synthesis

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 17))

Abstract

Ever since the double helix structure was first proposed for DNA, the problem of strand separation during replication has attracted much attention. When I was asked by the organizers of this meeting to give a general survey on the physical chemistry of DNA, I decided to focus my discussions on strand separation. At the molecular level however, even the simplest in vitro DNA replication system is rather complicated, and little quantitative information is available. Therefore, the discussions to follow are qualitative and conceptual in nature.

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Author information

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts, 02138, USA

    James C. Wang

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  1. James C. Wang
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Editor information

Editors and Affiliations

  1. Imperial Cancer Research Fund, London, England

    Ian Molineux

  2. University of Paris, Paris, France

    Masamichi Kohiyama

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© 1978 Plenum Press, New York

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Wang, J.C. (1978). Some Aspects of DNA Strand Separation. In: Molineux, I., Kohiyama, M. (eds) DNA Synthesis. NATO Advanced Study Institutes Series, vol 17. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0844-7_25

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  • DOI: https://doi.org/10.1007/978-1-4684-0844-7_25

  • Publisher Name: Springer, Boston, MA

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