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Cell Photosensitization by Psoralens and Porphyrins

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Primary Photo-Processes in Biology and Medicine

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Abstract

Mammalian cells in normal conditions contain a limited number of endogenous photosensitizers and consequently are relatively insensitive to light in the visible and near UV region. Other than in pathological conditions which lead to increased levels of endogenous sensitizers, sensitization phenomena are mainly due to exogenous photosensitizers. Because of the ability of sensitizers to induce specific photochemical reactions in vivo leading to cell injury and death, many such molecules have been considered as therapeutic agents.

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Author information

Authors and Affiliations

  1. Laboratoire de Biophysique, INSERM U.201, CNRS UA.481, Museum National d’Histoire Naturelle, 61, Rue Buffon, F-75005, Paris, France

    Giuliana Moreno

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  1. Giuliana Moreno
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Editors and Affiliations

  1. Muséum National d’Histoire Naturelle, Paris, France

    R. V. Bensasson

  2. University of Padua, Padua, Italy

    G. Jori

  3. Christie Hospital and Holt Radium Institute, Manchester, England

    E. J. Land

  4. Paisley College of Technology, Paisley, Scotland

    T. G. Truscott

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© 1985 Plenum Press, New York

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Moreno, G. (1985). Cell Photosensitization by Psoralens and Porphyrins. In: Bensasson, R.V., Jori, G., Land, E.J., Truscott, T.G. (eds) Primary Photo-Processes in Biology and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1224-6_19

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  • DOI: https://doi.org/10.1007/978-1-4684-1224-6_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1226-0

  • Online ISBN: 978-1-4684-1224-6

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