Abstract
A dozen years have passed since Allan Campbell (1962) suggested that prophages might associate with the host chromosome through an insertion mechanism accomplished by a reciprocal recombination event. We now know that insertion does occur for most temperate phage and that the insertion reaction is typically catalyzed by a phage-speci-fied pathway of recombination, which is notable for its localization to one or a small number of sites on the phage and host DNA (for reviews see Echols, 1971; Gottesman and Weisberg, 1971).
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Echols, H., Chung, S., Green, L. (1974). Site-Specific Recombination: Genes and Regulation. In: Grell, R.F. (eds) Mechanisms in Recombination. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2133-0_6
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DOI: https://doi.org/10.1007/978-1-4684-2133-0_6
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