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Measurement of Myocardial Blood Flow Using 133Xe

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Nuclear Cardiology

Part of the book series: Topics in Cardiovascular Disease ((TCAD))

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Abstract

In 1945, Kety and Schmidt1 devised a method to measure cerebral blood flow using a diffusible indicator, nitrous oxide. In 1949, Kety2 substituted 24Na and described the first practical method to measure blood flow using a radionuclide tracer. In the following years, some groups3–11 elaborated further on Kety’s work and developed methods for measuring myocardial blood flow by injection of diffusible tracers into a coronary artery or into the myocardium itself. The disappearance, or “washout,” of radioactivity was measured by an external radiation-detection system placed over the myocardium. Kety had shown that the rate of washout of the diffusible indicator from tissue to blood was a function of tissue blood flow.1,2,12

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References

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Authors and Affiliations

  1. Department of Medicine Southwestern Medical School, The University of Texas Health Science Center, Dallas, Texas, USA

    Robert W. Parkey, Frederick J. Bonte, Ernest M. Stokely, George C. Curry & James T. Willerson

Authors
  1. Robert W. Parkey
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  2. Frederick J. Bonte
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  3. Ernest M. Stokely
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  4. George C. Curry
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  5. James T. Willerson
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Editor information

Editors and Affiliations

  1. Department of Radiology, Baumritter Institute of Nuclear Medicine, Mount Sinai Medical Center and University of Miami School of Medicine, Miami Beach, Florida, USA

    Aldo N. Serafini , Albert J. Gilson  & William M. Smoak ,  & 

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© 1977 Springer Science+Business Media New York

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Parkey, R.W., Bonte, F.J., Stokely, E.M., Curry, G.C., Willerson, J.T. (1977). Measurement of Myocardial Blood Flow Using 133Xe. In: Serafini, A.N., Gilson, A.J., Smoak, W.M. (eds) Nuclear Cardiology. Topics in Cardiovascular Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2274-0_9

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  • DOI: https://doi.org/10.1007/978-1-4684-2274-0_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2276-4

  • Online ISBN: 978-1-4684-2274-0

  • eBook Packages: Springer Book Archive

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