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Chemotherapy of Manic-Depressive Disorder

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Brain Chemistry and Mental Disease

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 1))

Abstract

The term “affective disorders” is used for a group of mental illnesses with a primary disturbance of affect, and comprising those behavior disorders characterized principally by increased or decreased activity and thought, expressive of a predominating mood of depression or elation.

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References

  • Abdulla, Y. H., and Hamadah, K. 1970. 3,5-Cyclic adenosine mono-phosphate in depression and mania. Lancet 1:378.

    Article  PubMed  CAS  Google Scholar 

  • Akimoto, H. 1962. In Normothymics, “mood normalizers” by M. Schou. Brit. J. Psychiat. 109:803 (1963).

    Google Scholar 

  • Akimoto, H.; Nakakuki, M.; Honda, Y.; Takahashi, Y.; and Toyoda, J. 1961. Clinical evaluation of the effect of central stimulants, MAO inhibitors, and imipramine in the treatment of affective disorders. Proceedings of Third World Congress of Psychiatry 2:958.

    Google Scholar 

  • Andersen, H., and Kristiansen, E. S. 1959. Tofranil treatment of endogenous depression. Acta Psychiat. Scand. 34:387.

    Article  PubMed  CAS  Google Scholar 

  • Andreani, G.; Caselle, A.; and Martelli, G. 1958. Clinical and electrographic findings in the treatment of mania with lithium salts. G. Psichiat. Neuropat. 83:273.

    Google Scholar 

  • Angrist, B. M.; Gershon, S.; Levitan, S. J.; and Blumberg, A. G. 1968. Lithium induced “diabetes insipidus”-like syndrome. Compr. Psychiat. 11(no. 2):141.

    Article  Google Scholar 

  • Angst, J. 1966. Zur Aetiologie und Nosologie Endogener Depressiver Psychosen. Berlin: Springer-Verlag, p. 197.

    Book  Google Scholar 

  • Angst, J.; Dittrich, A.; and Grof, P. 1969. Course of endogenous affective psychoses and its modification by prophylactic administration of imipramine and lithium. Int. Pharmacopsychiat. 2:1.

    Article  Google Scholar 

  • Angst, J.; Weis, P.; Grof, P.; Baastrup, P.; and Schou, M. 1970. Lithium prophylaxis in recurrent affective disorders. Brit. J. Psychiat. 116(no. 535):604.

    Article  PubMed  CAS  Google Scholar 

  • Angyal, L. 1967. Clinical experiences with the application of halopendol to mental patients. Ther. Hung. 15:155.

    PubMed  CAS  Google Scholar 

  • Annell, A. I. 1969. Lithium in the treatment of children and adolescents. Acta Psyehiat. Scand. Suppl. 207:19.

    Article  Google Scholar 

  • Araki, I.; Ito, M.; Kostyuk, P.; Oscarsson, O.; and Oshima, I. 1965. The effects of alkaline cations on the responses of cat spinal neurons and their removal from the cell. Proc. Roy. Soc. (Biol.) 162:319.

    Article  CAS  Google Scholar 

  • Aronoff, M. S., and Epstein, R. S. 1969. Lithium failure in mania: A clinical study. Read at annual meeting of American Psychiatric Association, Bal Harbor, Florida.

    Google Scholar 

  • Atkinson, R. M., and Ditman, K. S. 1965. Tranylcypromine: A review. Clin. Pharmacol. Ther. 6:631.

    PubMed  CAS  Google Scholar 

  • Ayd, F. J. 1958. Drug-induced depression: Fact or fallacy? New York J. Med. 58:354.

    PubMed  Google Scholar 

  • Ayd, F. J. 1961. Psychopathic reactions to antidepressant drugs. J. Neuropsychiat. 2:119.

    PubMed  Google Scholar 

  • Baastrup, P. C. 1964. The use of lithium in manic-depressive psychosis. Compr. Psychiat. 5:396.

    Article  PubMed  CAS  Google Scholar 

  • Baastrup, P. C. 1967. Report to symposium, Lithium and Goitre, Risskov, Denmark.

    Google Scholar 

  • Baastrup, P. C., and Schou, M. 1967. Lithium as a prophylactic agent. Its effect against recurrent depressions and manic-depressive psychosis. Arch. Gen. Psychiat. 16:162.

    Article  PubMed  CAS  Google Scholar 

  • Baastrup, P. C. 1968. Supplementary information about lithium treatment of manic-depressive disorders. Acta Psychiat. Scand. Suppl. 203:149.

    Article  CAS  Google Scholar 

  • Baastrup, P. C.; Poulson, J. C; Schou, M.; Thomsen, K.; and Amidsen, A. 1970. Prophylactic lithium: Double blind discontinuation in manic-depressive and recurrent-depressive disorders. Lancet 2(no. 7668):326.

    Article  PubMed  CAS  Google Scholar 

  • Baillarger, J. 1853–1854. Note on the type of insanity with attacks characterized by two regular periods, one of depression and one of excitation. Bull. Acad. Nat. Med. (Paris) 19:340.

    Google Scholar 

  • Baker 1930. In Foundations of Child Psychiatry. E. Miller (ed.). 1st. Ed. New York: Pergamon Press (1968), p. 262.

    Google Scholar 

  • Baldessarini, R. J., and Stephens, J. H. 1970. Lithium carbonate for affective disorders. Arch. Gen. Psychiat. 22(no. 1):72.

    Article  PubMed  CAS  Google Scholar 

  • Ban, T. A. 1969. The rauwolfias. In Psychopharmacology, ch. 11. Baltimore: Williams & Wilkins, p. 222.

    Google Scholar 

  • Ban, T. A. 1969. The buterophenones. In Psychopharmacology, ch-12. Baltimore: Williams & Wilkins, p. 238.

    Google Scholar 

  • Ban, T. A. 1969. The thioxanthenes. In Psychopharmacology, ch. 13., Baltimore: Williams & Wilkins, p. 256.

    Google Scholar 

  • Ban, T. A.; Papathomopulos, E.; and Schwartz, L. 1962. Clinical studies with thioproperazine (Majeptil). Compr. Psychiat. 3:284.

    Article  PubMed  CAS  Google Scholar 

  • Barsa, J. A., and Kline, N. S. 1955. Treatment of 200 disturbed psychotics with reserpine. J.A.M.A. vol. 158.

    Google Scholar 

  • Barsa, J. A., and Saunders, J. C. 1962. Tranylcypromine in the treatment of chronic schizophrenics. Amer. J. Psychiat. 118:933.

    PubMed  CAS  Google Scholar 

  • Bauer, A. 1962. Clinical experiences with thioridazine (Mellaril) on mental syndromes. Comparison with chlorpromazine and promazine. Canad. Med. Assoc. J. 81:549.

    Google Scholar 

  • Bennett, I. F. 1962. The constellations of depression: Its treatment with nortriptyline. II. Clinical evaluation of nortriptyline. J. Nerv. Ment. Dis. 135:59.

    Article  Google Scholar 

  • Bennie, R. H., and Fell, G. S. 1969. Relapses during lithium therapy. Lancet 2:1252.

    Article  PubMed  CAS  Google Scholar 

  • Bercel, N. A. 1961. Clinical trial of thioridazine in private practice. Amer. Pract. Digest Treat. 12:44.

    Google Scholar 

  • Berens, S. C.; Bernstein, R. S.; Robbins, J.; and Wolff, J. 1969. The antithyroid effects of lithium. Paper presented at American Thyroid Association, Chicago, Illinois.

    Google Scholar 

  • Berens, S. C.; Wolff, J.; and Murphy, D. L. 1970. Lithium concentration by the thyroid. Submitted for publication.

    Google Scholar 

  • Berthiaume, M. 1959. Alteration of the clinical picture during Tofranil therapy. Canad. Psychiat. Assoc. J. Suppl. 4:187.

    Google Scholar 

  • Bratfos, O., and Haug, J. O. 1968. The course of manic depressive psychosis. Acta Psychiat. Scand. 44:89.

    Article  PubMed  CAS  Google Scholar 

  • Brune, G. G., and Himwich, H. E. 1963. Biogenic amines and behavior in schizophrenic patients. In Recent Advances in Biological Psychiatry. J. Wortis (ed.). vol. 5. New York: Plenum Press, p. 144.

    Google Scholar 

  • Bunney, W. E.; Brodie, H. K. H.; Murphy, D. L.; Goodwin, F. K. 1970. Studies of amine precursors and synthesis inhibitors in depression and mania. Presented to 123rd annual meeting of American Psychiatric Association, San Francisco.

    Google Scholar 

  • Burdock, E. I., and Hardesty, A. S. 1968. A psychological test for psychopathology. J. Abnorm. Psychol. 73:62.

    Article  PubMed  CAS  Google Scholar 

  • Cade, J. F. J. 1949. Lithium salts in the treatment of psychotic excitement. Med. J. Aust. 36:349.

    Google Scholar 

  • Cadoret, R. J.; Winokur, G.; and Clayton, P. J. 1970. Family history studies: VII. Manic depressive disease versus depressive disease. Brit. J. Psychiat. 116(no. 535):625.

    Article  PubMed  CAS  Google Scholar 

  • Chaffin, D. S. 1964. Phenothiazine-induced acute psychotic reaction: The “psychotoxicity” of a drug. Amer. J. Psychiat. 121:26.

    PubMed  CAS  Google Scholar 

  • Chess, S. 1970. Personal communication.

    Google Scholar 

  • Chu, J., and Fogel, E. J. 1962. Clinical evaluation of the thymol-eptic effect of tranylcypromine. J. Indiana Med. Assoc. 56:40.

    Google Scholar 

  • Clark, W. G., and del Giudice, J. (eds.) 1970. Principles of Psychopharmacology. New York: Academic Press.

    Google Scholar 

  • Clarke, J. 1960. Side-effects of phenelzine. Brit. Med. J. 1:1204.

    Article  Google Scholar 

  • Cole, J. O. 1960. Behavioral toxicity. In Drugs and Behavior. L. Uhr and J. G. Miller (eds.). New York: John Wiley and Sons, p. 375.

    Google Scholar 

  • Cole, L.; Griffith, C.; and Kaye, H. 1965. Anginal pain and depression. A preliminary investigation. Bis. Chest 48:584.

    Article  Google Scholar 

  • Cole, R. A., and Weiner, M. F. 1960. Clinical and theoretical observations on phenelzine (Nardil), an anti-depressant agent. Amer. J. Psychiat. 117:361.

    PubMed  CAS  Google Scholar 

  • Colombi, D., and Ferrio, L. 1965. Results with thioridazine administered to a group of patients with chronic psychoses. Riv. Sper. Freniat. 89:717.

    PubMed  CAS  Google Scholar 

  • Coppen, A. 1967. The biochemistry of affective disorders. Brit. J. Psychiat. 113:1237.

    Article  PubMed  CAS  Google Scholar 

  • Coppen, A.; Prange, A. J., Jr.; Whybrow, P. C.; Noguera, R.; and Paez, J. M. 1969. Methysergide in mania, a controlled trial. Lancet 2:338.

    Article  PubMed  CAS  Google Scholar 

  • Couleon, M.; Couleon, H.; Anne, L.; Blohorn, R.; Clerc, G.; and Guiraldo Trengualye, J. P. 1964. Treatment of states of psy-chomotor excitement, especially of acute mania by combination of thioridazine, Nembutal, and ECT. Ann. Med. Psychol. 122(II):752.

    CAS  Google Scholar 

  • Creak, E. M. 1952. A letter. Nervous Child 9:317.

    CAS  Google Scholar 

  • Davenport, V. D. 1950. Distribution of parenterally administered lithium in plasma, brain and muscle of rats. Amer. J. Physiol. 163:633.

    PubMed  CAS  Google Scholar 

  • D’Elia, G., and Rocco, P. G. 1963. Use of questionnaires in a clinico-pharmacological trial of Mellaril, Ann. Freniatria 76:358.

    Google Scholar 

  • Dewhurst, W. G. 1968. Methysergide in mania. Nature 219(no. 5153): 506.

    Article  PubMed  CAS  Google Scholar 

  • DiMascio, A.; Meuer, R. E.; and Stifler, L. 1968. Effects of imipramine on individuals varying in level of depression. Amer. J. Psychiat. 124(suppl.):55.

    PubMed  Google Scholar 

  • DiMascio, A., and Shader, R. I. 1968. Behavioral toxicity. In Psychopharmacology: A Review of Progress — 1957–1967. D.H. Efron (ed.). Washington, D.C.: U.S. Govt. Printing Office, p. 551.

    Google Scholar 

  • Dixon and Greeves 1885. In Foundations of Child Psychiatry. E. Miller (ed.). 1st Ed. New York: Pergamon Press (1968), p. 262.

    Google Scholar 

  • Domino, E. F. 1968. Substituted phenothiazine antipsychotics. In Psychopharmacology: A Review of Progress — 1957–1967. D.H. Efron (ed.). Washington, D.C.: U.S. Govt. Printing Office, p. 1045.

    Google Scholar 

  • Dousa, T., and Hechter, O. 1970. The effect of NaCl and LiCl on vasopressin-sensitive adenyl cyclase. Life Sci. 9(part I):765.

    Article  CAS  Google Scholar 

  • Drill, V. A. 1958. Pharmacology in Medicine. 2nd Ed. New York: McGraw-Hill.

    Google Scholar 

  • Entwistle, C.; Taylor, R. M.; and MacDonald, I. A. 1962. The treatment of mania with haloperidol (Serenace). Journal of Mental Science 108:373.

    PubMed  CAS  Google Scholar 

  • Esplin, D. W., and Zablocka, B. 1965. Central nervous system stimulants. Ch. 18. In The Pharmacological Basis of Therapeutics. S. L. Goodman and A. Gilman (eds.). 3rd Ed. New York: MacMillan, p. 352.

    Google Scholar 

  • Falret, J. P. 1853–1854. Clinical Lectures on Mental Medicine. General Symptomatology. Paris: Bailliere, p. 188.

    Google Scholar 

  • Falret, J. P. 1864. On Mental Diseases. Paris; Bailliere, p. 188.

    Google Scholar 

  • Fenichel, O. 1945. The Psychoanalytic Theory of Neurosis. New York: W. W. Norton, p. 413.

    Google Scholar 

  • Fieve, R. 1970. Lithium studies and manic-depressive illness. Presented to 60th annual meeting of American Psychopathological Assn., New York City.

    Google Scholar 

  • Fieve, R. R.; Platman, S. R.; and Plutchik, R.R. 1968a. The use of lithium in affective disorders. I. Acute endogenous depression. Amer. J. Psychiat. 125:487.

    PubMed  CAS  Google Scholar 

  • Fieve, R. R.; Platman, S. R.; and Plutchik, R. R. 1968b. The use of lithium in affective disorders. II. Prophylaxis of depression in chronic recurrent affective disorders. Amer. J. Psychiat. 125:492.

    PubMed  CAS  Google Scholar 

  • Filotto, J. et al. 1967. Thiothixene in the treatment of affective psychoses: A pilot study. Presented at Q.P.R.A. symposium on thioxanthenes, Montreal, Canada.

    Google Scholar 

  • Fink, M.; Kahn, R. L.; Karp, E.; Pollack, M.; Green, M. A.; Alan, B.; and Lefkowitz, H. J. 1961. Inhalant-induced convulsions. Arch. Gen. Psychiat. 4:259.

    Article  PubMed  CAS  Google Scholar 

  • Fish, B. 1968. Methodology in child psychopharmacology. In Psychopharmacology: A Review of Progress — 1957–1967. D. H. Efron (ed.). Washington, D.C.: U.S. Govt. Printing Office, p. 989.

    Google Scholar 

  • Fish, B., and Shapiro, T. 1965. A typology of children’s psychiatric disorders. I. Its application to a controlled evaluation of treatment. J. Amer. Acad. Child Psychiat. 4(no. 1):32.

    Article  PubMed  CAS  Google Scholar 

  • Fotel-Andersen, K., and Geert-Jorgensen, E. 1959. Treatment of endogenous depression with Tofranil. Ugeskr. Laeg. 121:1091.

    PubMed  CAS  Google Scholar 

  • Fries, H. 1969. Experience with lithium carbonate treatment at a psychiatric department in the period 1964-1967. Acta Psychiat. Scand. Suppl. 207:41.

    Article  Google Scholar 

  • Frommer, F. A. 1968. Depressive illness in childhood. In Recent Developments in Affective Disorders. A. Coppen and A. Walk (eds.). Brit. J. Psychiat. Spec. Pub. No. 2, p. 117.

    Google Scholar 

  • Fursham, P. H. 1965. The suprarenal glands (adrenal glands). In The Ciba Collection of Medical Illustrations, Endocrine System and Selected Metabolic Diseases. F. H. Netter (ed.). Vol. 4. Ciba Pharmaceutical Co., p. 84 and 105.

    Google Scholar 

  • Gattozzi, A. A. 1970. Lithium in the Treatment of Mood Disorders. Washington, D.C.: National Clearing House for Mental Health Information, Publication No. 5033.

    Google Scholar 

  • Gershon, S. 1968. Use of lithium salts in psychiatric disorders. Dis. Nerv. Syst. 29:51.

    PubMed  CAS  Google Scholar 

  • Gershon, S. 1970. Lithium in mania. Clin. Pharmacol. Ther. 11:168.

    PubMed  CAS  Google Scholar 

  • Gershon, S., and Trautner, E. M. 1956. Treatment of shock dependency by pharmacological agents. Med. J. Aust. 1:783.

    PubMed  CAS  Google Scholar 

  • Gershon, S., and Yuwiler, A. 1960. Lithium ion: A specific pharmacological approach to the treatment of mania. J. Neuropsychiat. 1:229.

    PubMed  CAS  Google Scholar 

  • Glessinger, B. 1954. Evaluation of lithium in treatment of psychotic excitement. Med. J. Aust. 41:277.

    Google Scholar 

  • Goldberg, L. I. 1964. Monoamine oxidase inhibitors. J.A.M.A. 190:456.

    Article  PubMed  CAS  Google Scholar 

  • Goldman, D. 1966. Drugs in treatment of psychosis. In Psychiatric Drugs. P. Solomon (ed.). New York: Grune and Stratton, p. 136.

    Google Scholar 

  • Goldstein, B. J.; Clyde, D. J.; and Caldwell, J. M. 1968. Clinical efficacy of the butyrophenones as anti-psychotic drugs. In Psychopharmacology: A Review of Progress — 1957–1967. D.H. Efron (ed.). Washington, D.C.: U.S. Govt. Printing Office, p. 1085.

    Google Scholar 

  • Gomez-Reino y Filgueira, J., and Fernandez-Vincente, L. 1962. Our experiences with Mellaril in endogenic manic and in chronic paranoid schizophrenia. Actas Luso Esp. Neurol. Psiquiat. p. 159.

    Google Scholar 

  • Goodman, L. S., and Gilman, A. Z. 1956. The Pharmacological Basis of Therapeutics. 2nd Ed. New York: MacMillan.

    Google Scholar 

  • Goodwin, F. K.; Murphy, D. L.; and Bunney, W. E., Jr. 1968. Lithium in mania and depression: A double-blind behavioral and biochemical study. Presented to annual meeting, American Psychiat. Assoc, Boston.

    Google Scholar 

  • Gradwell, G. B. 1960. Psychotic reactions and phenelzine. Brit. Med. J. 2:1018.

    Article  Google Scholar 

  • Greenfield, I.; Zuger, M.; Bleak, R. M; and Bakal, S. F. 1950. Lithium chloride intoxication. New York J. Med. 50:459.

    PubMed  CAS  Google Scholar 

  • Greenspan, I.; Green, R.; and Durrell, J. 1968. Retention and distribution patterns of lithium, a pharmacological tool in studying the pathophysiology of manic-depressive psychosis. Amer. J. Psychiat. 125:512.

    PubMed  CAS  Google Scholar 

  • Gross, H., and Kaltenback, E. 1961. Erfahrung mit dem Thioxanthenderivat Chlorprothixen in der klinischen Psychiatrie. Wien. Klin. Wschr. 73:64.

    PubMed  CAS  Google Scholar 

  • Guistino, P. 1953. II citrato di litio mel trattamento degli stati di eccitazione psicotica. Note Psychiat. 79:307.

    Google Scholar 

  • Haefner, H.; Heyder, B.; and Kitscher, I. 1965. Undesirable side-effects and complications with the use of neuroleptic drugs. Int. J. Neuropsychiat. 1:46.

    Google Scholar 

  • Hamilton 1903. In Foundations of Child Psychiatry. E. Miller (ed.) 1st Ed. New York: Pergamon Press (1968).

    Google Scholar 

  • Harms, E. 1952. Differential pattern of manic-depressive disease in childhood. Nervous Child 9:326.

    CAS  Google Scholar 

  • Hartigan, G. P. 1963. The use of lithium salts in affective disorders. Brit. J. Psychiat. 109:810.

    Article  PubMed  CAS  Google Scholar 

  • Haskovec, L., and Rysanek, I. 1967. The action of reserpine in imipramine resistant depressed. Psychopharmacologia (Berlin) 11:18.

    Article  CAS  Google Scholar 

  • Haskovec, L., and Soucek, I. 1968. Trial of methysergide in mania. Nature 219(no. 5153):507.

    Article  PubMed  CAS  Google Scholar 

  • Hekimian, L. J., and Gershon, S. 1967. Thioxanthenes: Some clinical and physiologic effects of a thioxanthene derivative, thio-thixene, in twenty newly hospitalized male schizophrenics. J. Clin. Pharmacol. 7:52.

    CAS  Google Scholar 

  • Hekimian, L. J.; Gershon, S.; Hardesty, A. S.; and Burdock, E. I. 1969. Drug efficacy and diagnostic specificity in manic-depressive illness and schizophrenia. Bis. Nerv. Syst. 30:747.

    CAS  Google Scholar 

  • Heninger, G. R., and Mueller, P. S. 1970. Carbohydrate metabolism in mania. Arch. Gen. Psychiat. 23:310.

    Article  PubMed  CAS  Google Scholar 

  • Herrera, J. J., and Vilaprino, J. J. 1964. Thioridazine in the treatment of manic-depressive psychosis. Acta Psiquiat. Psicol. Amer. Lat. 10:214.

    Google Scholar 

  • Ho, A. K. S.; Loh, H.; Craves, F.; Hitzeman, R.; and Gershon, S. 1970. The effect of prolonged lithium treatment on the synthesis rate and turnover of monoamines in brain regions of rats. Europ. J. Pharmacol. 10:72.

    Article  CAS  Google Scholar 

  • Hohn, R.; Gross, G. M.; Gross, M; and Lasagna, L. 1961. A double-blind comparison of placebo and imipramine in the treatment of depressed patients in a state hospital. J. Psychiat. Res. 1:76.

    Article  PubMed  CAS  Google Scholar 

  • Hollister, L. E. 1957. Complications from the use of tranquilizer drugs. New Eng. J. Med. 257:170.

    Article  PubMed  CAS  Google Scholar 

  • Hospital Tribune. Sept. 21, 1970, p. 3.

    Google Scholar 

  • Hudgens, R. W.; Tanna, V. L.; Harley, J. D.; and Leary, D. J., Jr. 1966. Visual hallucinations with iminodibenzyl antidepressants. J.A.M.A. 198:81.

    Article  Google Scholar 

  • Imlah, N. W. 1960. Overshooting action of phenelzine. Lancet 1:826.

    Article  Google Scholar 

  • Innes, I. R., and Nickerson, M. 1965. Anti-muscarinic or atropinic drugs. In The Pharmacological Basis of Therapeutics. S. L. Goodman and A. Gilman (eds.). 3rd Ed. New York: MacMillan, p. 521.

    Google Scholar 

  • Itil, T. 1968. Early clinical and EEG drug evaluation studies. Psychiatric Research Foundation of Missouri (St. Louis) Publication No. 19. Presented at Early Clinical Drug Evaluation Units meeting, Miami, Fla.

    Google Scholar 

  • Jacobsen, J. E. 1965. The hypomanic alert: A program designed for greater therapeutic control. Amer. J. Psychiat. 122:295.

    Google Scholar 

  • Jarvik, M. E. 1965. Drugs used in treatment of psychiatric disorders. In The Pharmacological Basis of Therapeutics. S. L. Goodman and A. Gilman (eds.). 3rd Ed. New York: MacMillan, p. 178.

    Google Scholar 

  • Johnson, G.; Gershon, S.; and Hekimian, L. J. 1968. Controlled evaluation of lithium and chlorpromazine in the treatment of manic states: An interim report. Compr. Psychiat. 9:563.

    Article  PubMed  CAS  Google Scholar 

  • Johnson, G.; Hekimian, L.; and Gershon, S. 1970. Differential drug responsiveness in psychiatric subjects. Presented to 8th annual ACNP meeting, San Diego, California.

    Google Scholar 

  • Johnson, G.; Maccarrio, M.; Gershon, S.; and Korein, J. 1970. The effects of lithium on EEG, behavior, and serum electrolytes. J. Nerv. Ment. Bis. 151:273.

    Article  CAS  Google Scholar 

  • Johnson, J., and Eilenberg, M. D. 1960. Psychotic reactions and phenelzine (Nardil). Brit. Med. J. 2:857.

    Article  Google Scholar 

  • Kassanin 1931. In Foundations of Child Psychiatry. E. Miller (ed.). 1st Ed. New York: Pergamon Press (1968), p. 262.

    Google Scholar 

  • Klein, D. F. 1965. Behavioral effects of imipramine and pheno-thiazines: Implications for a psychiatric pathogenetic theory and theory of drug action. In Recent Advances in Biological Psychiatry. J. Wortis (ed.). New York: Plenum Press, vol. 7, p. 273.

    Google Scholar 

  • Klein, D. F., and Davis, J. M. 1969. Diagnosis and Drug Treatment of Psychiatric Disorders. Baltimore: Williams & Wilkins, p. 222 and p. 313.

    Google Scholar 

  • Kline, N. S. 1954. Use of rauwolfia serpentina benth. In Neuro-psychiatric Conditions. Ann. N.Y. Acad. Sci. 59:107.

    Article  CAS  Google Scholar 

  • Kline, N. S. 1968. Lithium comes into its own (editorial). Amer. J. Psychiat. 125:150.

    Google Scholar 

  • Kloos, H. H. 1967. Experiences with neuroleptic drugs — mainly thioridazine (Mellaril R) in clinical psychiatry. Praxis 56:1434.

    PubMed  CAS  Google Scholar 

  • Kolb, L. C. (ed.). 1968. Noyes’ Modern Clinical Psychiatry. 7th Ed. Philadelphia: W. B. Saunders, p. 335.

    Google Scholar 

  • Kraepelin, E. 1909-1913. Thieme. 8th Ed. Leipzig.

    Google Scholar 

  • Kraepelin, E. 1913. Psychiatrie. Ein Lehrbuchfür Studierende und Ärzte. Leipzig.

    Google Scholar 

  • Kristjansen, P. 1962. In B. Gerle (ed.): Clinical observations of the side effects of haloperidol. Acta Psychiat. Scand. 40:65 (1964).

    Google Scholar 

  • Kruse, W., and Hoermann, M. G. 1960. Clinical evaluation of four anti-depressant drugs. Curr. Ther. Res. 2:111.

    PubMed  CAS  Google Scholar 

  • Kurland, A. A.; Cuervo, R.; and Krantz, J. C., Jr. 1960. The intravenous use of hexafluorodiethyl ether as a convulsant in psychiatric treatment. J. Neuropsychiat. 1:260.

    PubMed  CAS  Google Scholar 

  • Lang, A. E., and Moore, R. A. 1961. Acute toxic psychosis concurrent with phenothiazine therapy. Amer. J. Psychiat. 117:939.

    PubMed  CAS  Google Scholar 

  • Lasky, J. J.; Klett, J. C.; Caffey, E. M.; Bennet, L. J.; Rosenblum, M. P.; and Hollister, L. E. 1962. Drug treatment of schizophrenic patients. Dis. Nerv. Syst. 23:698.

    Google Scholar 

  • Laurell, B., and Ottosson, L. J. D. 1968. Prophylactic lithium? Letter to the editor. Lancet 2:1245.

    Article  PubMed  CAS  Google Scholar 

  • Lehmann, H. E., and Ban, T. A. 1970. Clinical use of other anti-psychotic agents. In Principles of Psychopharmacology. W. G. Clark and J. del Giudice (eds.). New York: Academic Press, p. 621.

    Google Scholar 

  • Lehmann, H. E., and Hanrahan, G. E. 1954. Chlorpromazine, a new inhibiting agent for psychomotor excitement and manic states. Arch. Neurol. 71:227.

    CAS  Google Scholar 

  • Leonhard, K. 1957. Aufteilung der Endogenen Psychosen. 1st Ed. Berlin.

    Google Scholar 

  • Leonhard, K. 1966. Aufteilung der Endogenen Psychosen. 3rd Ed. Berlin.

    Google Scholar 

  • Lipkin, K. M.; Dyrud, J.; and Meyer, G. G. 1970. The many faces of mania. Arch. Gen. Psychiat. (Chicago)22:262.

    CAS  Google Scholar 

  • Luby, E. 1968. Reserpine-like drugs — clinical efficacy. In Psychopharmacology: A Review of Progress1957-1967. D. H. Efron (ed.). Washington, D. C: U.S. Govt. Printing Office, p. 1077.

    Google Scholar 

  • Maggs, R. 1963. Treatment of manic illness with lithium carbonate. Brit. J. Psychiat. 109:56.

    Article  Google Scholar 

  • Malitz, S.; Hough, P. H.; and Lesse, S. 1956. Two year evaluation of chlorpromazine in clinical research and practice. Amer. J. Psychiat. 113:540.

    PubMed  Google Scholar 

  • Massaut, C.; Chantraine, J.; Meunce, E.; Pairoux, R.; Paguay, J.; Arnould, F.; Burton, P.; Tinant, M.; and Piersotte, J. 1962. Clinical study of 162 patients treated with a new neuroleptic: clopenthixol (Sordinol R), Acta Neurol. Belg. 62:651.

    PubMed  CAS  Google Scholar 

  • Mayer-Gross, W.; Slater, E.; and Roth, M. 1969. Clinical Psychiatry. 3rd Ed. London: Bailliere, Tindall & Cassell, p. 232.

    Google Scholar 

  • Mayfield, D., and Brown, R. G. 1966. The clinical laboratory and elec-troencephalographic effects of lithium. J. Psychiat. Res. 4:207.

    Article  PubMed  CAS  Google Scholar 

  • McCabe, M. S.; Reich, T.; and Winokur, G. 1970. Methysergide as a treatment for mania. Amer. J. Psychiat. 127:354.

    PubMed  CAS  Google Scholar 

  • McNeil Laboratories 1970. Personal communication, V. Slotnick.

    Google Scholar 

  • Melia, P. I. 1967. A pilot trial of lithium carbonate in recurrent affective disorders. J. Irish Med. Assoc. 60:160.

    CAS  Google Scholar 

  • Melia, P. I. 1970. Prophylactic lithium: A double-blind trial in recurrent affective disorders. Brit. J. Psychiat. 116:621.

    Article  PubMed  CAS  Google Scholar 

  • Meyler, L. 1966. Side effects of drugs: Adverse reactions as reported by the medical literature of the world 1963-1965. Vol. 5. New York: Excerpta Medica Foundation, p. 16.

    Google Scholar 

  • Miller, E. 1968. The problem of classification in child psychiatry. In Foundations of Child Psychiatry. 1st Ed. E. Miller (ed.). New York: Pergamon Press.

    Google Scholar 

  • Mills 1888. In Foundations of Child Psychiatry. E. Miller (ed.). 1st Ed. New York: Pergamon Press, p. 262.

    Google Scholar 

  • Moracci, E. 1931. Azione di alcuni sali applicati direttamente sui centri corticali sensitivo — motori del cane. Arch. Fisiol. 29:487.

    Google Scholar 

  • Murphy, D. L.; Goodwin, F. K.; and Bunney, W. E. 1969. Aldosterone and sodium response to lithium administration in man. Lancet 2:458.

    Article  PubMed  CAS  Google Scholar 

  • Noack, C. H., and Trautner, E. M. 1951. Lithium treatment of manic psychosis. Med. J. Aust. 2:219.

    PubMed  CAS  Google Scholar 

  • Noyes, A. P. 1954. Modern Clinical Psychiatry. 4th Ed. Philadelphia: W. B. Saunders.

    Google Scholar 

  • O’Connell, R. A. 1970. Leucocytosis during lithium carbonate treatment. Int. Pharmacopsychiat. 4:30.

    Google Scholar 

  • Penrose, L. 1945. Survey of cases of familial mental illness. Unpubl. manuscript, Ontario Dept. of Health.

    Google Scholar 

  • Perris, C. 1966. A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses. Acta Psychiat. Scand. Suppl., p. 189.

    Google Scholar 

  • Pfeiffer, C. Z.; Singh, M.; and Goldstein, L. 1969. Single dose-effect relationship of lithium on the electrical activity of cerebral cortex and of the heart. J. Clin. Pharmacol. 9:298.

    CAS  Google Scholar 

  • Pilkington, T. L. 1962. A report on Tofranil. Mental Deficiency 66:729.

    CAS  Google Scholar 

  • Platman, S. R. 1970. A comparison of lithium carbonate and chlor-promazine in mania. Amer. J. Psychiat. 127:351.

    PubMed  CAS  Google Scholar 

  • Platman, S. R., and Fieve, R. R. 1968. Lithium carbonate and plasma cortisol response in the affective disorders. Arch. Gen. Psychiat. 18:591.

    Article  PubMed  CAS  Google Scholar 

  • Plenge, P.; Mellerup, E. T.; and Rafaelsen, O. J. 1969. Effects of lithium on carbohydrate metabolism. Lancet 1:1012.

    Article  Google Scholar 

  • Poldinger, W. 1963. Combined administration of desipramine and reserpine or tetrabenazine in depressed patients. Psychophar-macologia (Berlin) 4:308.

    Article  Google Scholar 

  • Radomski, J. L.; Fuyat, H. N.; Nelson, A. A.; and Smith, P. K. 1950. The toxic effects, excretion and distribution of lithium chloride. J. Pharmacol. Exp. Ther. 100:429.

    PubMed  CAS  Google Scholar 

  • Ramsden, E. N. 1970. Cyclic A.M.P. in depression and mania. Lancet 2:108.

    Article  Google Scholar 

  • Rapp, M. S. 1970. Prophylactic haloperidol in incipient hypomania. Canad. Psychiat. Assoc. J. 15:73.

    CAS  Google Scholar 

  • Redlich, F. C., and Freedman, D. X. 1966. The Theory and Practice of Psychiatry. New York: Basic Books.

    Google Scholar 

  • Rees, L., and Davies, B. 1965. A study of the value of haloperidol in the management and treatment of schizophrenic and manic patients. Int. J. Neuropsychiat. 1:263.

    CAS  Google Scholar 

  • Rikovsky, S. 1964. Incidence of imipramine-induced psychoses. Acta Nervosa Superior. 6:181.

    Google Scholar 

  • Rissetto, G., and Gazzano, G. 1952. Variazioni del sangue periferi-co nella intossicazione sperimentale da sali di litio. Riv. Patol. Clin. 7:202.

    PubMed  CAS  Google Scholar 

  • Rochford, J. M.; Detre, T.; Tucker, G. J.; and Harrow, M. 1970. Neuropsychological impairments in functional psychiatric disease. Arch. Gen. Psychiat. 22:114.

    Article  PubMed  CAS  Google Scholar 

  • Samuels, A. J. 1951. Primary and secondary leucocyte changes following the intramuscular injection of epinephrine hydrochloride. J. Clin. Invest. 30:941.

    Article  PubMed  CAS  Google Scholar 

  • Sandoz Pharmaceuticals 1970. Computer search — personal communication, K. Tashiro.

    Google Scholar 

  • Saran, B. M. 1969. Lithium. Letter to the editor. Lancet 1:1208.

    Article  PubMed  CAS  Google Scholar 

  • Sargent, W., and Slater, E. 1963. An Introduction to Physical Methods of Treatment in Psychiatry. London: Livingstone.

    Google Scholar 

  • Sarwer-Foner, G. J.; Grauer, H.; MacKay, J.; and Koranyi, E. K. 1959. Depressive states and drugs. A study of the use of imipra-mine “Tofranil” in open psychiatric settings. Med. Serv. J. Canada 15:359.

    CAS  Google Scholar 

  • Sarwer-Foner, G. J.; Koranyi, E. K.; Meszaros, A.; and Grauer, H. 1959. Depressive states and drugs. II. The study of phenelzine dihydrogen sulfate (Nardil) in open psychiatric settings. Canad. Med. Assoc. J. 81:9.

    Google Scholar 

  • Schiele, B. C. 1967. Studies with clopenthixol and thiothixene. Presented to Symposium of the Thioxanthines, Montreal, Canada.

    Google Scholar 

  • Schou, M. 1957. Biology and pharmacology of the lithium ion. Pharmacological Reviews 9:17.

    PubMed  CAS  Google Scholar 

  • Schou, M. 1958. Lithium studies. 1. Toxicity. Acta Pharmacol. 15:70.

    Article  CAS  Google Scholar 

  • Schou, M. 1958. Lithium studies. 3. Distribution between serum and tissues. Acta Pharmacol. 15:115.

    Article  CAS  Google Scholar 

  • Schou, M. 1959. Lithium in psychiatric therapy. Psychopharmaco-logia (Berlin) 1:65.

    Article  CAS  Google Scholar 

  • Schou, M. 1962. Electrocardiographic changes during treatment with lithium and with drugs of the imipramine-type. Acta Psychiat. Scand. 38:331.

    Article  Google Scholar 

  • Schou, M. 1968. Lithium in psychiatry — A review. Psychopharmacology: A Review of Progress — 1957–1967. D. H. Efron (ed.). Washington, D.C.: U.S. Govt. Printing Office, p. 701.

    Google Scholar 

  • Schou, M. 1970. Personal communication in Lithium in the Treatment of Mood Disorders by A. Gattozzi. Washington, D.C.: National Clearing House for Mental Health Information, Publ. No. 5033, p. 81.

    Google Scholar 

  • Schou, M. 1970. Use of lithium. In Principles of Psychopharmacology. N. G. Clark and J. del Giudice (eds.). New York: Academic Press, p. 653.

    Google Scholar 

  • Schou, M.; Amidsen, A.; Jensen, S. E.; and Olsen, T. 1968. Occurrence of goitre during lithium treatment. Brit. Med. J. 3:710.

    Article  PubMed  CAS  Google Scholar 

  • Schou, M.; Juel-Nielson, N.; Stromgren, E.; and Voldby, H. 1954. The treatment of manic psychoses by the administration of lithium salts. J. Neurol. Neurosurg. Psychiat. 17:250.

    Article  PubMed  CAS  Google Scholar 

  • Sedvall, G.; Jonsson, B.; Pettersson, U.; and Levin, K. 1968. Effects of lithium salts on plasma protein bound iodine and uptake of I-131 in thyroid gland of man and rat. Life Sci. 7:1257.

    Article  CAS  Google Scholar 

  • Serry, M. 1969. Lithium retention and response. Lancet 1:1267.

    Article  PubMed  CAS  Google Scholar 

  • Sharpless, S. K. 1965. Hypnotics and sedatives. In The Pharmacological Basis of Therapeutics. S. L. Goodman and A. Gilman (eds.). 3rd Ed. New York: MacMillan, p. 132.

    Google Scholar 

  • Sher, N. 1962. Hallucinations after chlorpromazine in an otosclero-tic. Amer. J. Psychiat. 118:746.

    PubMed  CAS  Google Scholar 

  • Sherman, S. 1961. A clinical evaluation of Mellaril. Amer. J. Psychiat. 118:452.

    PubMed  CAS  Google Scholar 

  • Shopsin, B. 1970. Effects of lithium on thyroid function. Dis. Nerv. Syst. 31:237.

    PubMed  CAS  Google Scholar 

  • Shopsin, B.; Blum, M.; and Gershon, S. 1969. Lithium-induced thyroid disturbance: Case report and review. Compr. Psychiat. 10:215.

    Article  PubMed  CAS  Google Scholar 

  • Shopsin, B.; Friedman, R.; and Gershon, S. 1970. The lithium ion related and blood dyscrasias. Submitted for publication.

    Google Scholar 

  • Shopsin, B., and Gershon, S. 1970. Cortisol response to dexametha-sone suppression in hospitalized depressives and control patients. Arch. Gen. Psychiat. In press.

    Google Scholar 

  • Shopsin, B.; Gershon, S.; and Pinckney, L. 1969. The secretion of lithium in human mixed saliva: Effects of ingested lithium on electrolyte distribution in saliva and serum. Int. Pharmacopsychiat. 2:148.

    Google Scholar 

  • Shopsin, B.; Johnson, G.; and Gershon, S. 1970. Neurotoxicity with lithium; differential drug responsiveness. Int. Pharmacopsychiat. In press.

    Google Scholar 

  • Shopsin, B.; Kim, S. S.; and Gershon, S. 1970. A controlled study of lithium vs. chlorpromazine in acute schizophrenics. Presented at 15th Annual Conference — V.A. Cooperative Studies in Psychiatry, Houston, Texas. Accepted for publication, Brit. J. Psychiat..

    Google Scholar 

  • Shopsin, B.; Stern, S.; and Gershon, S. 1970. Altered carbohydrate metabolism during lithium treatment in hospitalized psychiatric patients: Absence of diagnostic specificity. Submitted for publication.

    Google Scholar 

  • Simon, W.; Wirt, A. L.; Wirt, R. D.; and Halloran, A. V. 1965. Long term follow-up study of schizophrenic patients. Arch. Gen. Psychiat. 12:510.

    Article  PubMed  CAS  Google Scholar 

  • Sivadon, P., and Chanoit, P. 1955. Clinical experience with lithium treatment of psychomotor excitation. Ann. Medicopsychol. 113:790.

    PubMed  Google Scholar 

  • Sletten, I. W., and Gershon, S. 1966. The premenstrual syndrome: A discussion of its pathophysiology and treatment with the lithium ion. Compr. Psychiat. 7(no. 3):198.

    Article  Google Scholar 

  • Spitzer, R. L.; Endicott, J.; and Fleiss, J. L. 1967. Instruments and recording forms for evaluating psychiatric status and history: rationale, method of development and description. Compr. Psychiat. 8:321.

    Article  PubMed  CAS  Google Scholar 

  • Spring, G. K.; Schweid, D.; Gray, C.; Steinberg, J.; and Harwitz, M. 1970. A double blind comparison of lithium and chlorpromazine in the treatment of manic states. Amer. J. Psychiat. 126:1306.

    PubMed  CAS  Google Scholar 

  • Spring, G. K.; Schweid, D.; Steinberg, J.; and Bond, D. 1969. Prophylactic use of lithium carbonate? J.A.M.A. 208:1901.

    Article  PubMed  CAS  Google Scholar 

  • Stromgren, L. S., and Stromgren, E. 1962. In Normothymics “mood normalizers” by M. Schou Brit. J. Psychiat. 109:803.

    Google Scholar 

  • Talso, P. J., and Clarke, R. W. 1951. Excretion and distribution of lithium in the dog. Amer. J. Physiol. 166:202.

    PubMed  CAS  Google Scholar 

  • Trautner, E. M.; Morris, R.; Noack, C. H.; and Gershon, S. 1955. The excretion and retention of ingested lithium and its effect on the ionic balance of man. Med. J. Aust. 2:280.

    Google Scholar 

  • Van der Velde, C. D., and Gordon, M. W. 1969. Manic-depressive illness, diabetes mellitus and lithium carbonate. Arch. Gen. Psychiat. 21:478.

    Article  PubMed  Google Scholar 

  • Van der Velde, C. D. 1970. Effectiveness of lithium carbonate in the treatment of manic-depressive illness. Amer. J. Psychiat. 127:345.

    PubMed  Google Scholar 

  • Von Trostorff, S. 1968. Über die hereditäre Belastung bei den bipolaren und monopolaren phasisehen Psychosen. Schweiz. Arch. Neurochir. Psychiat. 102:235.

    Google Scholar 

  • Wiggers, S. 1968. Lithiumpavirkning af glandula thyreoidea. Ugeskr. Laeg. 130/37:1523.

    PubMed  CAS  Google Scholar 

  • Wingard, C. 1961. Questions and answers. J.A.M.A. 175:340.

    Article  Google Scholar 

  • Winokur, G., and Clayton, P. 1967. Family history studies: II. Sex differences and alcoholism in primary affective illness. Brit. J. Psychiat. 113:973.

    Article  PubMed  CAS  Google Scholar 

  • Wirt, R. D., and Simon, W. 1959. Differential Treatment and Prognosis in Schizophrenia. Springfield, Ill.: Charles C Thomas.

    Google Scholar 

  • Wolpert, E. A., and Mueller, P. 1969. Lithium carbonate in the treatment of manic-depressive disorders. Arch. Gen. Psychiat. 21:155.

    Article  PubMed  CAS  Google Scholar 

  • Zall, H.; Therman, P. O. G.; and Myers, J. M. 1968. Lithium carbonate: A clinical study. Amer. J. Psychiat. 125:549.

    PubMed  CAS  Google Scholar 

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Shopsin, B., Gershon, S. (1971). Chemotherapy of Manic-Depressive Disorder. In: Ho, B.T., McIsaac, W.M. (eds) Brain Chemistry and Mental Disease. Advances in Behavioral Biology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3057-8_22

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